Review
Plant Sciences
Ke Yang, Jing Qiu, Zecheng Huang, Ziwei Yu, Wenjun Wang, Huiling Hu, Yu You
Summary: Schisandra chinensis and Schisandra sphenanthera, known as bei-wuweizi and nan-wuweizi in Chinese respectively, are highly similar plants with traditional uses in Chinese medicine for treating various conditions. They have similar chemical compositions and pharmacological activities, with potential drug interactions due to their inhibitory effects on CYP3A and P-gp. Further research is needed to explore their traditional uses and differences for clinical applications.
JOURNAL OF ETHNOPHARMACOLOGY
(2022)
Article
Integrative & Complementary Medicine
Shiqi Huang, Dongdong Zhang, Yuze Li, Hao Fan, Yuanyuan Liu, Wenli Huang, Chong Deng, Wei Wang, Xiaomei Song
Summary: Schisandra sphenanthera is a medicinal herb with a wide range of bioactivities, including antitumor, anti-oxidant, anti-inflammatory, osteoblastic, immune regulation, neuroprotective, kidney protection, hepatoprotective, and antiviral activities. There is still a need for further studies on resource availability, quality control measures, in-depth in vivo pharmacological study, and clinical application.
AMERICAN JOURNAL OF CHINESE MEDICINE
(2021)
Article
Microbiology
Chuan You, Dan Qin, Yumeng Wang, Wenyi Lan, Yehong Li, Baohong Yu, Yajun Peng, Jieru Xu, Jinyan Dong
Summary: Beneficial interactions between endophytes and plants are crucial for plant growth and metabolite accumulation. Plant-derived triterpenoids were found to promote the growth of endophytic bacteria and fungi, which in turn enhanced host plant growth and secondary metabolite productions. This study suggests a strategy for constructing synthetic communities (SynComs) based on the screening of secondary metabolites, where bacteria and fungi work together to promote plant health.
Article
Agricultural Engineering
Xiaorui Wang, Min Yan, Xinxin Wang, Zhiting Wu, Jia Zhou, Chan Wang, Ruidun Chen, Xiaolu Qin, Heyu Yang, Haiyan Wei, Wei Gu
Summary: This study evaluated the phenotypic diversity of Schisandra sphenanthera fruits on a large scale and investigated the relationship between environmental factors and fruit phenotypes. Significant correlations were found between phenotype and environmental factors, with some factors having direct effects on phenotype and others having indirect effects. The study also proposed a machine learning method to predict the phenotype of S. sphenanthera in different environments with high accuracy.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Applied
Nguyen Thi Mai, Vu Van Doan, Hoang Thi Tuyet Lan, Bui Thi Mai Anh, Nguyen Huy Hoang, Bui Huu Tai, Nguyen Xuan Nhiem, Pham Hai Yen, Seon Ju Park, Yohan Seo, Wan Namkung, Seung Hyun Kim, Phan Van Kiem
Summary: Phytochemical investigation of Schisandra sphenanthera leaves led to the isolation of new compounds, with schirubrisin B showing strong cytotoxic effects on prostate and breast cancer cells.
NATURAL PRODUCT RESEARCH
(2021)
Article
Biotechnology & Applied Microbiology
Boshi Sun, Peng Wang, Meng Guan, Entong Jia, Qian Li, Jun Li, Ziyun Zhou, Pengda Ma
Summary: This study investigated the gene expression and metabolite content in different tissues of Schisandra sphenanthera through transcriptome and metabolome analyses. It was found that the root and fruit had high levels of lignan accumulation, while the leaves had lower levels. Transcription factor analysis revealed the importance of MYB, bHLH, and ERF transcription factors in secondary metabolism regulation. Additionally, a weighted gene co-expression network analysis identified genes related to lignan accumulation.
Article
Plant Sciences
Shiqi Huang, Yuanyuan Liu, Yuze Li, Hao Fan, Wenli Huang, Chong Deng, Xiaomei Song, Dongdong Zhang, Wei Wang
Summary: Two new dibenzocyclooctadiene lignans, schisphenlignan M and N, along with nine known analogues, were isolated from the root bark of Schisandra sphenanthera. These lignans showed cytotoxic activities against human lung and colon cancer cell lines, indicating potential anti-cancer properties.
PHYTOCHEMISTRY LETTERS
(2021)
Review
Chemistry, Organic
Lu Guo, Pingping Tang
Summary: Schisandraceae, a traditional Chinese herb known for its anti-hepatitis bioactivity, has diverse and unique structures that have caught the interest of synthetic chemists. Recent efforts towards the total synthesis of schisandra triterpenoid have been summarized.
CHINESE JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Nutrition & Dietetics
Mengzhen Jia, Li Zhou, Yuanyuan Lou, Xiaoqing Yang, Hangyu Zhao, Xinshou Ouyang, Yanjie Huang
Summary: Objective: This review aims to summarize the nutritional components and medicinal properties of Schisandra chinensis, as well as the advancements in quality control studies. Through literature review and analysis, the main nutritional components of S. chinensis and their benefits to human health are identified, and future research directions are suggested.
FRONTIERS IN NUTRITION
(2023)
Article
Biochemistry & Molecular Biology
Jiumn-Yih Wu, Hsiou-Yu Ding, Tzi-Yuan Wang, Yun-Rong Zhang, Te-Sheng Chang
Summary: Rare Ganoderma triterpenoid saponins were discovered and two novel Ganoderma saponins were successfully produced through enzymatic catalysis using four Bacillus enzymes, showing increased aqueous solubility. This study lays the foundation for the production of novel Ganoderma triterpenoid saponins in the future.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Oncology
Maobo Huang, Yuanfei Zhou, Dongzhu Duan, Chuanyu Yang, Zhongmei Zhou, Fubing Li, Yanjie Kong, Yi-Ching Hsieh, Ruihan Zhang, Wenping Ding, Weilie Xiao, PemaTenzin Puno, Ceshi Chen
Summary: The study reveals the important role of ubiquitin enzymes in therapeutic resistance in TNBC cells, suggesting that small molecule inhibitors can restore sensitivity to treatment. Specifically, PC3-15 was found to block auto-ubiquitination of HECTD3/UbcH5b and inhibit UbcH5b-mediated p62 ubiquitination, leading to increased sensitivity to lapatinib in TNBC.
Review
Pharmacology & Pharmacy
Feng Zhang, Jianxiu Zhai, Nan Weng, Jie Gao, Jun Yin, Wansheng Chen
Summary: This review summarized the effects of Wu Wei Zi extract and its major lignan components on cytochrome P450 and P-glycoprotein activities, as well as the absorption, distribution, metabolism, and elimination of the major lignans. The results enhance our understanding of the drug-drug interaction mechanisms involving Wu Wei Zi.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Medicinal
Yu-pei Yang, Yu-qing Jian, Yong-bei Liu, Qing-ling Xie, Huang-he Yu, Bin Wang, Bin Li, Cai-yun Peng, Wei Wang
Summary: The study found that Heilaohuacid G can treat rheumatic arthritis by inhibiting the NF-kappa B pathway, thus inhibiting inflammatory reactions and the proliferation of RA-FLS cells.
PHYTOTHERAPY RESEARCH
(2022)
Article
Chemistry, Medicinal
Jun-nan Hu, Yi-ming Wang, Hao Zhang, Hui-ping Li, Zi Wang, Mei Han, Shen Ren, Shan Tang, Shuang Jiang, Wei Li
Summary: The study found that Scheme B has a protective effect on cisplatin-induced rat intestinal crypt epithelial cell injury. It achieves this by reducing oxidative stress, inhibiting cell apoptosis and inflammation, and repairing intestinal barrier function.
PHYTOTHERAPY RESEARCH
(2023)
Article
Crystallography
Ren-Song Chen, Jiang-Hai Ye, Yu-Ling Luo, Chuan-Yan Xu, Juan Zou, Jing-Jie Zhang
Summary: The substance is C24H30O7, with an orthorhombic crystal structure and space group P2(1)2(1)2(1). The cell parameters are a = 11.4194(5) angstrom, b = 13.4657(6) angstrom, c = 14.7549(7) angstrom, and the cell volume is 2268.86(18) angstrom(3) containing 4 molecules. The R-gt(F) value is 0.0535, the wR(ref)(F-2) value is 0.1239, and the temperature is 273(2) K.
ZEITSCHRIFT FUR KRISTALLOGRAPHIE-NEW CRYSTAL STRUCTURES
(2023)
Article
Chemistry, Multidisciplinary
Qian Wu, Yubo Cui, Guifeng Xia, Jinlong Yang, Shuming Du, Xinhong Xiong, Li Yang, Dong Xu, Xu Deng, Jiaxi Cui
Summary: Passive daytime radiative cooling (PDRC) technology, while promising for global spacing cooling, faces limitations in practical application due to reduced cooling effectiveness caused by wear and dirt contamination. Researchers have developed a renewable armor structure using fluorinated hollow glass microspheres to enhance the anti-fouling and cooling properties of PDRC coatings. The coatings exhibit high solar reflectance and thermal emittance, leading to significant temperature reduction below ambient temperature.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Qiang Bei, Bei Zhang, Kaifeng Wang, Shiming Zhang, Guichuan Xing, Clement Cabanetos
Summary: The power conversion efficiency (PCE) of organic solar cells (OSCs) has reached 20% in recent years, thanks to the advantages of organic photoactive materials. Benzothiadiazole (BT) has attracted significant research attention as a building block of OSCs. OSCs based on BT structure have shown diversity, and the increasing PCE values indicate a promising future for OSCs. This review analyzes the progress made in the last decades, focusing on effective BT small-molecules and BT polymers for OSCs. The structure-property relationships, donor-acceptor matching criteria, and morphology control approaches are discussed. The remaining challenges and a personal perspective on the future advancement of OSCs are summarized.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Rong He, Dandan Tang, Ningge Xu, Heng Liu, Kun Dou, Xuejun Zhou, Fabiao Yu
Summary: Nasopharyngeal carcinoma (NPC) is a common malignant tumor of the head and neck, with a high incidence in China and Southeast Asian countries. In this study, a novel near-infrared fluorescent probe, SNAFL-GSH, was designed and synthesized for the detection of glutathione (GSH). The probe showed selective detection of GSH and the ability to distinguish normal and cancer cells. It has great potential for application in the diagnosis and evaluation of NPC.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhukang Guo, Baijiang Jin, Yile Fang, Lian Jin, Song Li, Yan Deng, Zhu Chen, Hui Chen, Yuanying Zhang, Rabia Usman, Nongyue He
Summary: This study isolated primary cells that can be stably passaged from spontaneous tumors of genetically engineered pancreatic ductal adenocarcinoma model mice and used an autonomously developed automated screening instrument for efficient nucleic acid aptamer screening. The obtained aptamers were affinity verified at the cellular level. The study also investigated the impact of cell growth environment difference on the recognition ability of aptamers and confirmed the targeting ability and drug loading ability of the aptamer.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Zhongshan Yang, Qiqi Zhang, Hui Song, Xin Chen, Jiwei Cui, Yanhui Sun, Lequan Liu, Jinhua Ye
Summary: Methane chemistry is a significant area of research in catalysis. Converting methane into value-added chemicals is desirable but challenging due to its high C-H bonding energy and lack of pi bonding or unpaired electrons. Photocatalytic partial oxidation of methane to liquid oxygenates is a promising technology for achieving high efficiency and selectivity under mild conditions. The choice and activation of oxidants are crucial for its performance.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Peng Shan, Jing Liao, Jiayi Li, Chengyan Wang, Jie Zhou, Linqiang Mei, Yunlu Dai, Qiang Wang, Wenyan Yin
Summary: This study reports an oral radioprotectant Gel@GYY that combines a gelatin-based hydrogel and a pH-responsive hydrogen sulfide donor. Gel@GYY has excellent adhesion and sustained release properties, allowing it to release H2S in the gastrointestinal tract and effectively scavenge free radicals induced by radiation. It also reduces inflammation and has biodegradable properties.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lu Liu, Ziyi Liu, Jingnan Cui, Guiling Ning, Weitao Gong
Summary: The development of new metal-free heterogeneous catalysts has been the subject of extensive research. In this study, a new Troger's base (TB)-derived porous organic polymer (POPs) was designed and prepared by integrating multifunctional monomers. The resulting polymer, which combines the advantages of pillar[5]arene macrocycle and TB moiety, exhibited enhanced catalytic performance in Knoevenagel condensation and CO2 conversion, serving as an effective metal-free catalyst. This work provides a new strategy for fabricating metal-free heterogeneous catalysts based on macrocyclic POPs.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leyong Zhou, Changyin Yang, Weitao Dou, Tongxia Jin, Haibo Yang, Lin Xu
Summary: This review summarizes the application of micro/nanofluidic techniques in constructing supramolecular assemblies of different scales, and highlights the advantages of these techniques over conventional synthesis methods. Furthermore, it emphasizes the potential of micro/nanofluidic systems in improving our understanding of supramolecular self-assembly processes.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Yanchao Jin, Suixiaochen Chen, Peiwen Huang, Xiongjian Chen, Chun-Yan Lin, Li-Ping Li, Xiao Chen, Rui Ding, Jianxi Liu, Riyao Chen
Summary: In this study, magnesium and coconut shell carbon were used to disinfect water by adsorbing copper(II) and converting dissolved oxygen to hydrogen peroxide through Mg corrosion. The copper was enriched on the carbon surface and efficiently catalyzed the hydrogen peroxide to inactivate E.coli. The process showed promising disinfection performance both in laboratory experiments and real wastewater treatment.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Haihong Lai, Zehong Chen, Hao Zhuo, Yijie Hu, Xuan Zhao, Jiwang Yi, Hongzhi Zheng, Ge Shi, Yifan Tong, Ling Meng, Xinwen Peng, Linxin Zhong
Summary: By altering the pyrolysis route of cellulose nanofiber, the structural defects of carbon aerogels can be reduced, leading to improved compressibility and stress retention, as well as higher stress sensor sensitivity and temperature coefficient.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lina Guo, Jinsong Ding, Wenhu Zhou
Summary: Bacteria-based tumor therapy has resurfaced due to the revolution of tumor immunotherapy, offering unique solutions for traditional tumor treatments. Bacteria with active tropism can selectively colonize tumor sites and suppress tumor growth through various mechanisms, making them attractive tools for tumor treatment. This critical review introduces recent advances in bacteria-based tumor therapy, including bacterial properties, their benefits for tumor therapy, anti-tumor mechanisms, challenges, and future perspectives.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Lan Liang, Chuanbin Wang, Xukai Lu, Yunan Sun, Beibei Yan, Ning Li, Guanyi Chen, Li'an Hou
Summary: This study investigates the interactions between phenol and benzaldehyde in the ECH process through experiments and theoretical calculations. The results show that phenol can accelerate the conversion of benzaldehyde, while benzaldehyde inhibits the conversion of phenol. The research provides a theoretical basis for the application of ECH in practical bio-oil upgrading.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Pengcheng Fan, Yuhao He, Junan Pan, Ning Sun, Qiyu Zhang, Chen Gu, Kang Chen, Weinan Yin, Longlu Wang
Summary: This study focuses on the recent progress in hydrogen evolution reaction (HER) based on photothermal effect. It introduces the main pathways of photothermal conversions applied in H2 evolution, summarizes the functions of the photothermal effect, and presents a method to improve the catalytic system through thermal means. The study also discusses the challenges and outlook in this promising area.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Leiduo Lai, Hongyu Zhou, Yichen Hong, Mengfan Luo, Yang Shi, Heng Zhang, Zhaokun Xiong, Gang Yao, Bo Lai
Summary: In this study, a facile ammonia reduction strategy was proposed and a novel FeVO3-x catalyst was synthesized for the activation of peroxymonosulfate (PMS) to degrade the pharmaceutical carbamazepine (CBZ). The results showed that the system could rapidly degrade CBZ and generate various active species involved in the degradation process.
CHINESE CHEMICAL LETTERS
(2024)
Article
Chemistry, Multidisciplinary
Tangxin Xiao, Xiuxiu Li, Liangliang Zhang, Kai Diao, Zheng-Yi Li, Xiao-Qiang Sun, Leyong Wang
Summary: This study presents the construction of a supramolecular light harvesting system based on sequential energy transfer. The system demonstrates tunable fluorescence emission through self-assembly of polymers into nanoparticles, achieving efficient two-step light harvesting.
CHINESE CHEMICAL LETTERS
(2024)