期刊
CHILDS NERVOUS SYSTEM
卷 30, 期 5, 页码 959-962出版社
SPRINGER
DOI: 10.1007/s00381-013-2296-0
关键词
Hypertrophic olivary degeneration; Gadolinium enhancement; Posterior fossa surgery; Guillain-Mollaret triangle; Cerebellar mutism
资金
- Deutsche Kinderkrebsstiftung (German Childhood Cancer Foundation)
Hypertrophic olivary degeneration (HOD) is a rare transsynaptic form of degeneration occurring secondary to the disruption of the dentato-rubro-olivary pathway (Guillain-Mollaret triangle). HOD can be caused by ischemic, hemorrhagic, traumatic, or neoplastic lesions, and it can also occur following posterior fossa surgery. MRI characteristics of HOD include T2 signal increase and hypertrophy. To date, blood-brain barrier disruption has not been reported in HOD. Here, we present the first case of HOD with temporary gadolinium enhancement in a 10-year-old child 7 months after resection of a posterior fossa medulloblastoma. The recognition of gadolinium enhancement as a radiological feature of HOD may help to distinguish between this benign secondary condition and tumor recurrence.
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