Article
Pediatrics
Deqiang Luo, Wei Dai, Lei Lei, Xueying Cai
Summary: Our study demonstrated that changes in SV, evaluated by noninvasive ultrasound combined with PLR, can effectively evaluate fluid responsiveness in children under mechanical ventilation after congenital cardiac surgery.
Article
Medicine, General & Internal
Zhiyong Zhao, Zhongwei Zhang, Qionghua Lin, Lihua Shen, Pengmei Wang, Shan Zhang, Zhili Xia, Fangfang Li, Qian Xing, Biao Zhu
Summary: This study found that changes in cardiac index (CI) induced by a unilateral passive leg raising test in spontaneously breathing patients can estimate fluid responsiveness with high sensitivity and specificity, and is not inferior to that induced by a bilateral PLR test.
FRONTIERS IN MEDICINE
(2022)
Article
Critical Care Medicine
Jing-jie Wan, Jun Chen, Li Xu, Ke Peng, Jin Xie
Summary: This study evaluated the predictive values of peak velocity variation and passive leg raising for fluid responsiveness in postoperative critically ill elderly patients. The results showed that passive leg raising-induced changes in peak velocity variation accurately predicted fluid responsiveness and was applicable for postoperative critically ill elderly patients.
Article
Sport Sciences
Emiliano Ce, Massimo Venturelli, Angela Valentina Bisconti, Stefano Longo, Anna Pedrinolla, Giuseppe Coratella, Federico Schena, Fabio Esposito
Summary: This study compared the effects of small muscle mass endurance training and passive stretching training on local and systemic vascular responsiveness. The findings showed that both training modalities had similar effects on improving brachial artery dilation capacity, while small muscle mass endurance training was more effective in improving femoral artery blood flow.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2022)
Article
Critical Care Medicine
Temistocle Taccheri, Francesco Gavelli, Jean-Louis Teboul, Rui Shi, Xavier Monnet
Summary: In mechanically ventilated patients with Vt = 6 mL/kg, the effects of PLR can be assessed by changes in PPV. When using IVCDV, it should be expressed in percentage rather than absolute changes. The effects of the Vt challenge can be assessed through changes in PPV, but not in IVCDV due to the small diagnostic threshold compared to the reproducibility of this variable.
Article
Critical Care Medicine
Youcef Azeli, Alfredo Bardaji, Eneko Barberia, Vanesa Lopez-Madrid, Jordi Blade-Creixenti, Laura Fernandez-Sender, Gil Bonet, Elena Rica, Susana Alvarez, Alberto Fernandez, Christer Axelsson, Maria F. Jimenez-Herrera
Summary: The trial did not demonstrate the benefits of performing PLR during OHCA in terms of improving survival to hospital discharge. Furthermore, there were no adverse effects found in the study.
Article
Multidisciplinary Sciences
Clemence Roy, Gary Duclos, Cyril Nafati, Mickael Gardette, Alexandre Lopez, Bruno Pastene, Eliott Gaudray, Alain Boussuges, Francois Antonini, Marc Leone, Laurent Zieleskiewicz
Summary: This study confirms the association between LV-LS and preload, but the variations in LV-LS after PLR are not a discriminating criterion to predict fluid responsiveness in ICU patients with ACF.
Article
Critical Care Medicine
Ignacio Oulego-Erroz, Sandra Terroba-Seara, Paula Alonso-Quintela, Antonio Rodriguez-Nunez
Summary: This study found that respiratory variation in aortic blood flow peak velocity can help predict the immediate response to a fluid challenge in hemodynamically unstable neonates under mechanical ventilation, providing potential guidance for individualized fluid resuscitation in critically ill neonates.
PEDIATRIC CRITICAL CARE MEDICINE
(2021)
Article
Critical Care Medicine
Rui Shi, Francesca Moretto, Dominique Prat, Frederic Jacobs, Jean-Louis Teboul, Olfa Hamzaoui
Summary: This study aimed to evaluate whether the changes in arterial pulse pressure (PP) and pulse pressure variation (PPV) during passive leg raising (PLR) can be used to assess preload responsiveness in patients with spontaneous breathing activity. The results showed that the changes in PP during PLR had a fair ability to evaluate preload responsiveness, even when norepinephrine was administered.
JOURNAL OF CRITICAL CARE
(2022)
Article
Biology
Andrius Pranskunas, Egle Gulbinaite, Aiste Navickaite, Zivile Pranskuniene
Summary: This study compared the systemic hemodynamic changes in healthy individuals during morning and evening passive leg-raising (PLR) tests and found no significant differences between the two.
Article
Critical Care Medicine
Jihad Mallat, Malcolm Lemyze, Marc-Olivier Fischer
Summary: In mechanically ventilated patients with acute circulatory failure, changes in PVI induced by PLR accurately predict fluid responsiveness.
JOURNAL OF CRITICAL CARE
(2024)
Article
Clinical Neurology
Chiara Robba, Antonio Messina, Denise Battaglini, Lorenzo Ball, Iole Brunetti, Matteo Bassetti, Daniele R. Giacobbe, Antonio Vena, Nicolo' Patroniti, Maurizio Cecconi, Basil F. Matta, Xiuyun Liu, Patricia R. M. Rocco, Marek Czosnyka, Paolo Pelosi
Summary: This study observed the effects of PLR test, FC, and NE on cerebral autoregulation in severe COVID-19 patients, finding that PLR test had a negative impact on CA. Individualized strategies to assess both hemodynamic and cerebral needs are necessary for patients at high risk of neurological complications.
FRONTIERS IN NEUROLOGY
(2021)
Article
Physiology
Raphael Giraud, Bojana Vujovic, Benjamin Assouline, Ivo Neto Silva, Karim Bendjelid
Summary: The study demonstrates that ScvO(2) variations induced by passively leg raising (PLR) can be a reliable and minimally invasive parameter for predicting fluid responsiveness in mechanically ventilated critically ill patients after cardiac surgery.
PHYSIOLOGICAL REPORTS
(2021)
Article
Anesthesiology
Jihad Mallat, Marc-Olivier Fischer, Maxime Granier, Christophe Vinsonneau, Marie Jonard, Yazine Mahjoub, Fawzi Ali Baghdadi, Sebastien Preau, Fabien Poher, Olivier Rebet, Belaid Bouhemad, Malcolm Lemyze, Mehdi Marzouk, Emmanuel Besnier, Fadi Hamed, Nadeem Rahman, Osama Abou-Arab, Pierre-Gregoire Guinot
Summary: Passive leg raising-induced changes in pulse pressure variation accurately predict fluid responsiveness in critically ill patients on mechanical ventilation, with a small grey zone.
BRITISH JOURNAL OF ANAESTHESIA
(2022)
Article
Anesthesiology
Antonio Messina, Giovanni Sotgiu, Laura Saderi, Gianmaria Cammarota, Lorenzo Capuano, Davide Colombo, Victoria Bennett, Didier Payen, Daniel De Backer, Paolo Navalesi, Maurizio Cecconi
Summary: This study investigated the impact of different definitions and timings on the reliability of PLR assessment, finding that the best correlation with PLR performance was seen with a 15% increase in CI or SVI after 10 minutes. Additionally, the number of responders was higher 10 minutes after FC administration compared to 15 and 30 minutes.
MINERVA ANESTESIOLOGICA
(2022)