A Native Ternary Complex Trapped in a Crystal Reveals the Catalytic Mechanism of a Retaining Glycosyltransferase

Substrate-Guided Front-Face Reaction Revealed by Combined Structural Snapshots and Metadynamics for the PolypeptideN-Acetylgalactosaminyltransferase 2

(2014) Erandi Lira-Navarrete et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Theoretical study of enzymatic catalysis explains why the trapped covalent intermediate in the E303C mutant of glycosyltransferase GTB was not detected in the wild-type enzyme

(2014) Adela Bobovská et al.   GLYCOBIOLOGY

A theoretical study on the catalytic mechanism of the retaining α-1,2-mannosyltransferase Kre2p/Mnt1p: the impact of different metal ions on catalysis

(2014) Adela Bobovská et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A computational and experimental study of O-glycosylation. Catalysis by human UDP-GalNAc polypeptide:GalNAc transferase-T2

(2014) Hansel Gómez et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Formation of a Covalent Glycosyl-Enzyme Species in a Retaining Glycosyltransferase

(2013) Víctor Rojas-Cervellera et al.   CHEMISTRY-A EUROPEAN JOURNAL

Structure-function relationships of membrane-associated GT-B glycosyltransferases

(2013) D. Albesa-Jove et al.   GLYCOBIOLOGY

Substrate-Assisted and Nucleophilically Assisted Catalysis in Bovine α1,3-Galactosyltransferase. Mechanistic Implications for Retaining Glycosyltransferases

(2013) Hansel Gómez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Essential role of glutamate 317 in galactosyl transfer by α3GalT: a computational study

(2012) Hansel Gómez et al.   CARBOHYDRATE RESEARCH

Mechanistic Insights into the Retaining Glucosyl-3-phosphoglycerate Synthase from Mycobacteria

(2012) Saioa Urresti et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Retaining Glycosyltransferase Mechanism Studied by QM/MM Methods: Lipopolysaccharyl-α-1,4-galactosyltransferase C Transfers α-Galactose via an Oxocarbenium Ion-like Transition State

(2012) Hansel Gómez et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The Molecular Mechanism of Enzymatic Glycosyl Transfer with Retention of Configuration: Evidence for a Short-Lived Oxocarbenium-Like Species

(2011) Albert Ardèvol et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic evidence for a front-side, SNi-type reaction in a retaining glycosyltransferase

(2011) Seung Seo Lee et al.   Nature Chemical Biology

Mechanistic Insight into Enzymatic Glycosyl Transfer with Retention of Configuration through Analysis of Glycomimetic Inhibitors

(2010) James C. Errey et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Trapping and characterization of covalent intermediates of mutant retaining glycosyltransferases

(2010) Naoto Soya et al.   GLYCOBIOLOGY

ABO(H) Blood Group A and B Glycosyltransferases Recognize Substrate via Specific Conformational Changes

(2008) Javier A. Alfaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Polymethylated Polysaccharides fromMycobacteriumSpecies Revisited

(2008) Mary Jackson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Glycosyltransferases: Structures, Functions, and Mechanisms

(2007) L.L. Lairson et al.   Annual Review of Biochemistry