Article
Medicine, General & Internal
Israel Gotsman, Andre Keren, Offer Amir, Donna R. Zwas
Summary: The study found that increased body composition indices, including body mass index, fat-free mass index, and fat mass index, were associated with better survival in patients with heart failure. The strongest association was seen with fat-free mass index, showing a graded increase in survival.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Article
Cardiac & Cardiovascular Systems
Tim Christen, Renee de Mutsert, Roelof AJ. Smit, Ko Willems van Dijk, Hildo J. Lamb, Frits R. Rosendaal, J. Wouter Jukema, Stella Trompet
Summary: This study investigated the association between leptin and heart function and subclinical cardiovascular disease, considering the confounding effect of body fat. The results showed that the association between leptin and heart function and subclinical cardiovascular disease was attenuated after adjusting for body fat. The relationship between genetically-determined leptin concentration and coronary heart disease risk was inconclusive.
NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
(2023)
Article
Medicine, General & Internal
Bernhard Ohnewein, Zornitsa Shomanova, Vera Paar, Albert Topf, Peter Jirak, Lukas Fiedler, Christina Granitz, Vincent Van Almsick, Dilvin Semo, Naufal Zagidullin, Anna-Maria Dieplinger, Juergen Sindermann, Holger Reinecke, Uta C. Hoppe, Rudin Pistulli, Lukas J. Motloch
Summary: ARNI therapy improves clinical symptoms and biochemical parameters in HFrEF patients, and may also affect lipid metabolism and glucose metabolism.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Yilan Ge, Jiamin Liu, Lihua Zhang, Yan Gao, Bin Wang, Xiuling Wang, Jing Li, Xin Zheng
Summary: Higher lean body mass, not fat mass, was associated with lower 1-year mortality among heart failure patients.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Endocrinology & Metabolism
Rapheeporn Khwanchuea, Chuchard Punsawad
Summary: This study found a negative correlation between leptin and 25(OH)D levels at 30% and 40% body fat percentage. There were differences in various body composition factors between boys and girls.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Geriatrics & Gerontology
Katsuhiko Ohori, Toshiyuki Yano, Satoshi Katano, Hidemichi Kouzu, Suguru Honma, Kanako Shimomura, Takuya Inoue, Yuhei Takamura, Ryohei Nagaoka, Masayuki Koyama, Nobutaka Nagano, Takefumi Fujito, Ryo Nishikawa, Tomoyuki Ishigo, Ayako Watanabe, Akiyoshi Hashimoto, Tetsuji Miura
Summary: The study retrospectively analyzed data from 198 HF patients and found that higher body fat mass was associated with lower short-term cardiac event risk in HF patients, while muscle wasting was not significantly associated with cardiac events.
Article
Cardiac & Cardiovascular Systems
Satish Kenchaiah, Jingzhong Ding, J. Jeffrey Carr, Matthew A. Allison, Matthew J. Budoff, Russell P. Tracy, Gregory L. Burke, Robyn L. McClelland, Andrew E. Arai, David A. Bluemke
Summary: The study found that pericardial fat volume was associated with incident heart failure (HF), especially in women and men. The risk of HF was higher in women with an increase in PFV compared to men. Elevated PFV was linked to a greater risk of HF with preserved ejection fraction. The study suggests that pericardial fat may play a role in the development of HF in both sexes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2021)
Article
Geriatrics & Gerontology
Masaaki Konishi, Hidehiro Kaneko, Hidetaka Itoh, Satoshi Matsuoka, Akira Okada, Kentaro Kamiya, Tadafumi Sugimoto, Katsuhito Fujiu, Nobuaki Michihata, Taisuke Jo, Norifumi Takeda, Hiroyuki Morita, Kouichi Tamura, Hideo Yasunaga, Issei Komuro
Summary: Weight loss and short/middle-term weight gain in patients with repeated hospitalization for heart failure are associated with high in-hospital mortality.
JOURNAL OF CACHEXIA SARCOPENIA AND MUSCLE
(2023)
Article
Cell Biology
Maria Conte, Aurelia Santoro, Salvatore Collura, Morena Martucci, Giuseppe Battista, Alberto Bazzocchi, Cristina Morsiani, Federica Sevini, Miriam Capri, Daniela Monti, Claudio Franceschi, Stefano Salvioli
Summary: Perilipin 2 (PLIN2) is a protein involved in lipid storage and metabolism in non-adipose tissues and circulating PLIN2 (cPLIN2) has been associated with certain types of cancer. The levels of cPLIN2 do not change with age, but are higher in women than in men; they strongly correlate with BMI, fat and lean mass, and the proinflammatory adipokine leptin. This suggests that cPLIN2, possibly regulated by leptin, could be used as a proxy for body adiposity.
Article
Nutrition & Dietetics
Shing-Hwa Liu, Yu-Xuan Chen, Huei-Ping Tzeng, Meng-Tsan Chiang
Summary: Low-carbohydrate and high-fat diets can cause lipid metabolism disturbance and fat accumulation, but fish oil supplementation can improve these adverse effects.
Article
Endocrinology & Metabolism
Oddrun Kristiansen, Manuela Zucknick, Trine M. Reine, Svein O. Kolset, Thomas Jansson, Theresa L. Powell, Guttorm Haugen, Tore Henriksen, Trond M. Michelsen
Summary: The study suggests that placental weight is the main mediator linking pregestational BMI and gestational weight gain to birthweight and neonatal fat mass percentage. Maternal mediators only partially mediate the effect of pBMI, while placental weight is the main mediator in this association.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2021)
Article
Nutrition & Dietetics
Lotte E. Vlug, Esther G. Neelis, Jonathan C. K. Wells, Mary S. Fewtrell, Wendy L. M. Kastelijn, Joanne F. Olieman, Marijn J. Vermeulen, Jorine A. Roelants, Dimitris Rizopoulos, Rene M. H. Wijnen, Edmond H. H. M. Rings, Barbara A. E. de Koning, Jessie M. Hulst
Summary: The study aimed to assess the growth and body composition changes in infants receiving parenteral nutrition (PN) after intestinal surgery and found compromised anthropometric parameters, decreased fat mass, and adequate fat-free mass in the first 6 months due to intestinal failure. Male and female infants responded differently to PN in terms of fat mass index.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Georgios Zisis, Yang Yang, Quan Huynh, Kristyn Whitmore, Maria Lay, Leah Wright, Melinda J. Carrington, Thomas H. Marwick
Summary: The use of handheld ultrasound to assess residual congestion in patients with acute decompensated heart failure can help predict the risk of readmission and death. Heart failure nurses are capable of obtaining images and providing diagnostic reports that are predictive of patient outcomes.
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
(2022)
Article
Physiology
Diego Araiza-Garaygordobil, Luis A. Baeza-Herrera, Rodrigo Gopar-Nieto, Fabio Solis-Jimenez, Alejandro Cabello-Lopez, Pablo Martinez-Amezcua, Vianney Sarabia-Chao, Hector Gonzalez-Pacheco, Daniel Sierra-Lara Martinez, Jose Luis Briseno-De la Cruz, Alexandra Arias-Mendoza
Summary: This study evaluated the association of pulmonary congestion assessed by LUS with cardiovascular outcomes in STEMI patients after reperfusion therapy. The findings suggest that pulmonary congestion identified by LUS is significantly associated with increased risk of adverse cardiovascular events, particularly heart failure and cardiogenic shock. Integration of LUS as part of initial risk stratification in STEMI patients may provide important prognostic information.
FRONTIERS IN PHYSIOLOGY
(2022)
Article
Biochemistry & Molecular Biology
Ivona Mitu, Cristina-Daniela Dimitriu, Cristina Preda, Ovidiu Mitu, Irina-Iuliana Costache, Radu-Stefan Miftode, Manuela Ciocoiu
Summary: This research aimed to establish a hierarchy of the influence of various biological markers and body composition parameters on preventing, diagnosing, and managing Metabolic Syndrome (MetS). Based on a cross-sectional cohort study, it was found that patients with MetS had higher levels of uric acid and CRP but lower levels of adiponectin compared to patients without MetS. The top predictive markers for the prevalence of MetS were HDL, insulin, and adiponectin:leptin ratio, while the top body composition parameters were trunk fat-free percentage, waist-height ratio, and trunk fat percentage.