Article
Agriculture, Dairy & Animal Science
Graziella Orso, Mikhail M. Solovyev, Serena Facchiano, Evgeniia Tyrikova, Daniela Sateriale, Elena Kashinskaya, Caterina Pagliarulo, Hossein S. Hoseinifar, Evgeniy Simonov, Ettore Varricchio, Marina Paolucci, Roberta Imperatore
Summary: With the increasing global population, the production of animal proteins becomes crucial, but aquaculture may lead to impaired growth and diseases in fish. This study explored the impact of phytochemicals such as tannins on intestinal inflammation and microbiota, with results indicating that tannins can improve the health status of fish.
Article
Agriculture, Dairy & Animal Science
Roberta Imperatore, Baldassare Fronte, Daniel Scicchitano, Graziella Orso, Maria Marchese, Serena Mero, Rosario Licitra, Elena Coccia, Marco Candela, Marina Paolucci
Summary: The large-scale fish farming industry requires a significant amount of animal-based feed, leading to the depletion of aquatic species. The development of alternative plant-based feed is hindered by its inflammatory effects on fish. This study used zebrafish as a model to investigate the potential of tannins to alleviate intestinal inflammation caused by a plant-based diet.
Article
Environmental Sciences
Xiaohui Ren, Jinjie Zhang, Yuqi Huang, Wen Yang, Kaihong Lu, Jinyong Zhu
Summary: This study investigated the response of freshwater gastropod Bellamya aeruginosa to toxic cyanobacterial stress. The results showed changes in the gastropod's gut microbial composition and gut metabolites after exposure to toxic cyanobacteria. The study reveals the underlying mechanisms of gut microbes in the gastropod's adaptation to toxic cyanobacterial stress.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Wenting Lin, Kan Li, Yingjun Qin, Xing Han, Xiaohui Chen, Yuan Ren
Summary: In this study, zebrafish were exposed to the benzodiazepine drug flunitrazepam (FLZ) for 30 days, and the results showed that FLZ disrupted the balance of gut microbiota, leading to pathological damage to the intestine and increased intestinal permeability. FLZ also interfered with nucleotide metabolism and amino acid biosynthesis in the brain, causing pathological changes. This study elucidated the molecular mechanisms of FLZ on the microbiota-gut-brain axis and provided a theoretical basis for the ecological environmental risk assessment of psychoactive substances.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Yitian Yu, Qi Zhang, Guangfu Liu, Yu Deng, Jian Kang, Fan Zhang, Tao Lu, Liwei Sun, Haifeng Qian
Summary: This study investigated the acute neurotoxicity of Microcystis aeruginosa on zebrafish and found that it seriously damaged neurotransmitter conduction in the nervous system and brain information storage and transmission, making zebrafish more susceptible to neurological diseases. The research offers a new perspective on the neurotoxicity risk of cyanobacterial blooms.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Agriculture, Dairy & Animal Science
Nienke de Groot, Fernando Farinas, Carolina G. Cabrera-Gomez, Francisco J. Pallares, Guillermo Ramis
Summary: Controlling gut inflammation is crucial in managing gut disorders in weaned piglets. This study evaluated the inflammatory response in the intestines of piglets during the post-weaning period, showing a sustained inflammation for at least 15 days post-weaning and changes in the expression of cytokines and immunoglobulins in the intestine.
JOURNAL OF ANIMAL SCIENCE
(2021)
Article
Environmental Sciences
Tianxu Zhang, Yan Zhang, Jiayun Xu, Zhenguang Yan, Qianhang Sun, Yi Huang, Shuping Wang, Shuo Li, Binbin Sun
Summary: Ammonia stress was found to negatively impact intestinal inflammation, antioxidant system, and microbiome of the Asian clam, leading to tissue damage. Inflammatory responses were more severe and antioxidant system damage was more pronounced, while ammonia stress altered intestinal microbial diversity and composition, particularly affecting Proteobacteria and Aeromonas.
ENVIRONMENTAL POLLUTION
(2021)
Article
Fisheries
Yanyan Shi, Xingyu Cao, Zhidong Ye, Yiyuan Xu, Yiming Wang, Zhipeng Li, Wei Hang, Ning He
Summary: Adding Schizochytrium sp. to the diet significantly enhances the pathogen resistance of zebrafish, increases the abundance of beneficial bacteria, and reduces potential pathogens, thereby promoting the health of zebrafish.
Article
Medicine, Research & Experimental
Lucas Casagrande, Maria Jose Pastre, Aline Rosa Trevizan, Roberto Kenji Nakamura Cuman, Ciomar Aparecida Bersani-Amado, Joao Luis Garcia, Marcelo Biondaro Gois, Debora de Mello Goncales Sant'Ana, Gessilda de Alcantara Nogueira-Melo
Summary: This study investigated the effects of acute oral infection with T. gondii on the intestinal tissue structure, enteric nervous system, and inflammatory markers in mice. The results showed a significant increase in serotonin-immunoreactive cells and inflammation in the intestinal mucosa and neural tissue. This study contributes to the understanding of the pathophysiological mechanisms of intestinal inflammation in humans.
Article
Gastroenterology & Hepatology
Seth D. Merkley, Samuel M. Goodfellow, Yan Guo, Zoe E. R. Wilton, Janie R. Byrum, Kurt C. Schwalm, Darrell L. Dinwiddie, Rama R. Gullapalli, Vojo Deretic, Anthony Jimenez Hernandez, Steven B. Bradfute, Julie G. In, Eliseo F. Castillo
Summary: Expression of Atg5 in intestinal myeloid cells prevents dysbiosis and excessive intestinal inflammation by limiting IL-12 production. Mice with a genetic deletion of Atg5 in myeloid cells showed severe intestinal inflammation characterized by increased IFN-gamma production. Exacerbated colitis was linked to excess IL-12 secretion from Atg5-deficient myeloid cells and gut dysbiosis. Restoration of the intestinal microbiota or genetic deletion of IL-12 attenuated the intestinal inflammation in Atg5-deficient mice.
JOURNAL OF CROHNS & COLITIS
(2022)
Article
Microbiology
Junwei Li, Yang Liu, Jiaxing Niu, Changwei Jing, Ning Jiao, Libo Huang, Shuzhen Jiang, Lei Yan, Weiren Yang, Yang Li
Summary: This study investigated the effects of supplementing paraformic acid (PFA) to the diet of broiler chickens on intestinal development, inflammation, and microbiota. The results showed that PFA supplementation improved intestinal development, suppressed intestinal inflammation, and changed gut microbiota composition in broiler chickens.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Environmental Sciences
Giridhar Babu Anam, Dinneswara Reddy Guda, Young-Ho Ahn
Summary: The study investigated the response of Microcystis aeruginosa to phytohormone exposure under terpinolene stress. Results showed that terpinolene inhibited growth and photosynthetic activities of M. aeruginosa while stimulating microcystins production through oxidative stress and antioxidant defense mechanisms. Hormones like IAA and BSL played critical roles in enhancing antioxidant defense mechanisms and microcystins production under terpinolene stress.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Gastroenterology & Hepatology
Werner C. Albrich, Tarini Shankar Ghosh, Sinead Ahearn-Ford, Flora Mikaeloff, Nonhlanhla Lunjani, Brian Forde, Noemie Suh, Gian-Reto Kleger, Urs Pietsch, Manuel Frischknecht, Christian Garzoni, Rossella Forlenza, Mary Horgan, Corinna Sadlier, Tommaso Rochat Negro, Jerome Pugin, Hannah Wozniak, Andreas Cerny, Ujjwal Neogi, Paul W. O'Toole, Liam O'Mahony
Summary: Protection against SARS-CoV-2 infection and its clinical sequelae requires coordinated metabolic and immune responses. The role of gut microbiota in regulating these responses and its association with disease outcomes has not been thoroughly investigated.
Review
Cell Biology
Natalia Kurilenko, Aliia R. Fatkhullina, Aleksandra Mazitova, Ekaterina K. Koltsova
Summary: Atherosclerosis is a lipid-driven chronic inflammatory disease characterized by the formation and growth of atherosclerotic plaques in arteries, and is a major predisposing factor for stroke and heart attack. Immun-mediated mechanisms are implicated in the disease progression, with cytokines playing a key role in regulating atherosclerosis. Increased levels of pro-inflammatory cytokines are always associated with the progression of atherosclerosis.
Article
Biochemistry & Molecular Biology
Kai Kudo, Takashi Kobayashi, Kosuke Kasai, Hiroyuki Nozaka, Toshiya Nakamura
Summary: Salmon nasal cartilage proteoglycan (PG) was orally administered to mice, and its effects on the small intestine were examined. The PG digest recovered from the intestine showed consistent properties with the actinase-digested PG prior to administration. Chondroitin sulfate, a sugar chain of PG, was found to be resistant to digestion in the mouse small intestine, and chondroitin sulfates showed a suppressive effect on colon cancer cells.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
(2023)
Article
Environmental Sciences
Yitian Yu, Qi Zhang, Zhenyan Zhang, Shuyidan Zhou, Mingkang Jin, Dong Zhu, Xiaoru Yang, Haifeng Qian, Tao Lu
Summary: Knowledge of the dissemination and emergence of antibiotic resistance genes (ARGs) in the plant rhizosphere is important for evaluating the risk they pose to soil planetary health. In this study, we analyzed the changes in the rhizosphere antibiotic resistome during the enrichment process of the rhizosphere microbiome in Arabidopsis thaliana. We found that plants selectively enriched beneficial bacteria with many ARGs, and the wheat rhizosphere had a higher abundance of ARGs compared to other crops. These findings highlight the potential threat to human health from the dissemination of ARGs, despite their beneficial functions in the plant rhizosphere.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Environmental Sciences
Fan Zhang, Nuohan Xu, Zhenyan Zhang, Qi Zhang, Yaohui Yang, Zhitao Yu, Liwei Sun, Tao Lu, Haifeng Qian
Summary: The rhizosphere microbiome is crucial for plant growth and acts as an important interface for resource exchange between plants and the soil environment. This study analyzed the variations of bacterial and fungal communities in the rhizosphere of four crop species during successive cultivation and found that specific microorganisms that benefit plant growth decreased in abundance over time, while potentially pathogenic fungi increased. The co-occurrence network analysis showed that bacterial and fungal communities under maize were more stable than those under other crops. The findings highlight the importance of indigenous soil flora in determining plant growth and suggest the potential use of critical microorganisms to control crop growth and yield.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2023)
Article
Marine & Freshwater Biology
Yan Wang, Kepin Ni, Zhenyan Zhang, Nuohan Xu, Chaotang Lei, Bingfeng Chen, Qi Zhang, Liwei Sun, Yiling Chen, Tao Lu, Haifeng Qian
Summary: The emergence and transmission of antibiotic resistance genes (ARGs) and virulence factors (VFs) pose health risks to the ecosystem and humans. Understanding how non-antibiotic antimicrobial agents drive the expression of ARGs and VFs in freshwater ecosystems, however, remains large challenges.
AQUATIC TOXICOLOGY
(2023)
Article
Environmental Sciences
Guoyan Qin, Qi Zhang, Ziyao Zhang, Yiling Chen, Jichao Zhu, Yaohui Yang, W. J. G. M. Peijnenburg, Haifeng Qian
Summary: In this study, the impact of the fungicide difenoconazole on the gut microbial community of Enchytraeus crypticus and the soil microbiome was investigated. The results showed that difenoconazole treatment reduced body weight and increased oxidative stress levels in E. crypticus. The fungicide also altered the composition and structure of the gut microbial community and impaired the abundance of beneficial bacteria in the soil, affecting the stability of the soil-soil fauna microecology. Additionally, the study revealed the enrichment of bacterial genes involved in detoxification and virus genes involved in the carbon cycle, showing their ecological importance under pesticide stress.
ENVIRONMENTAL POLLUTION
(2023)
Article
Engineering, Environmental
Bingfeng Chen, Zhenyan Zhang, Qi Zhang, Nuohan Xu, Tao Lu, Tingzhang Wang, Wenjie Hong, Zhengwei Fu, Josep Penuelas, Michael Gillings, Haifeng Qian
Summary: Antimicrobial peptides are a promising class of antimicrobials that can combat antibiotic resistance crisis. A global study on the diversity, hosts, and resistance potential of these peptides is lacking. This research analyzed 52,515 metagenome-assembled genomes to investigate the diversity and number of antimicrobial peptides in different habitats. The number of peptides was highest in the human gut microbiome, and their hosts varied across habitats. The risk of resistance genes to human health was quantified, with those conferring resistance to multiple AMPs and polymyxin B posing the highest threat.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Wei Lin, Zhenyan Zhang, Yiling Chen, Qi Zhang, Mingjing Ke, Tao Lu, Haifeng Qian
Summary: This study investigated the effects of glyphosate on six common cyanobacterial species and found that the growth of five species was promoted to different degrees, while only Pseudanabaena was inhibited. Phylogenetic analysis revealed that Pseudanabaena, which is more closely related to plants, was sensitive to glyphosate. Additionally, the study demonstrated that glyphosate served as a source of phosphorus and accelerated cyanobacterial growth.
JOURNAL OF ENVIRONMENTAL SCIENCES
(2023)
Article
Engineering, Environmental
Ming-Kang Jin, Qi Zhang, Yu-Tian Yang, Cai-Xia Zhao, Jian Li, Hongjie Li, Haifeng Qian, Dong Zhu, Yong-Guan Zhu
Summary: Worldwide, the use of pyrethroids, such as cypermethrin, is widespread as insecticides, but their impact on the soil microbiome and non-target soil fauna is not well understood. In this study, we investigated the effects of cypermethrin on the bacterial communities and antibiotic resistance genes (ARGs) in the soil and gut of Enchytraeus crypticus using genetic sequencing and qPCR. The results showed that cypermethrin exposure led to an increase in potential pathogens in the soil and gut microbiome of E. crypticus, disrupting the microbiome structure and immune system. The co-occurrence of potential pathogens, ARGs, and mobile genetic elements revealed an increased risk of pathogenicity and antibiotic resistance. Structural equation modeling demonstrated that ARG dissemination was promoted by both mobile genetic elements and the ratio of core to non-core bacterial abundance. Overall, this study provides important insights into the environmental risk of cypermethrin on the dissemination of ARGs in the soil and non-target soil fauna.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Engineering, Environmental
Bingfeng Chen, Zhenyan Zhang, Tingzhang Wang, Hang Hu, Guoyan Qin, Tao Lu, Wenjie Hong, Jun Hu, Josep Penuelas, Haifeng Qian
Summary: We created a global map using a machine-learning model to predict marine microplastic pollution. The results showed that microplastics accumulate in subtropical gyres and near polar seas. Our study also identified areas with high microplastic pollution and high potential for biodegradation, but the limited number of samples hindered accurate predictions.
JOURNAL OF HAZARDOUS MATERIALS
(2023)
Article
Environmental Sciences
Nuohan Xu, Hang Hu, Yan Wang, Zhenyan Zhang, Qi Zhang, Mingjing Ke, Tao Lu, Josep Penuelas, Haifeng Qian
Summary: River microbiotas play a critical role in geochemical processes and ecological functions of rivers, but their response to environmental drivers is sensitive. Understanding the geographic patterns of river microbial traits can provide important insights into river health and function.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Horticulture
Leidong Hong, Yanlai Yao, Chaotang Lei, Chunlai Hong, Weijing Zhu, Fengxiang Zhu, Weiping Wang, Tao Lu, Xingjiang Qi
Summary: Declined symptoms seriously damaged the growth and development of Myrica rubra, but the mechanisms involved in this decline are largely unknown. This study compared various factors in the rhizospheric soil of healthy and declined trees and found that planting bayberry aggravated soil acidification and led to significant changes in nutrient-metal element correlation. Microbial communities and metabolites also showed differences between healthy and declined trees. The study provides new insights into the causes of decline in bayberry trees and can assist in prevention and treatment based on plant-soil-microbe interactions.
SCIENTIA HORTICULTURAE
(2023)
Article
Chemistry, Physical
Zimo Lou, Xiaofei Wen, Ludi Song, Chen Yan, Hongxu Chen, Tao Lu, Jianming Yu, Xinhua Xu, Jiansheng Li
Summary: To achieve precise removal of trace FLO in the presence of various high-concentration interferents in water, a novel oxygen vacancy engineered molecular imprinted TiO2 (MI-TiO2-x) cathode material was developed. MI-TiO2-x exhibited enhanced recognition and accelerated interfacial charge transfer due to its molecular imprinted sites and oxygen vacancy, respectively. It demonstrated superior dehalogenation performance, outperforming most recent electrocatalysts, and showed resistance to co-existing interferents. In an electro-reductive and biological coupling system, MI-TiO2-x effectively removed the antibacterial activity of FLO in swine wastewater and eliminated the abundance of FLO resistance genes. This study provides insights into the rational design of noble-metal-free electrocatalysts for the remediation of low-concentration organic halides and highlights the importance of dehalogenation treatment in mitigating ecological risks.
APPLIED CATALYSIS B-ENVIRONMENTAL
(2023)
Article
Ecology
Yitian Yu, Qi Zhang, Zhenyan Zhang, Nuohan Xu, Yan Li, Mingkang Jin, Guoqiang Feng, Haifeng Qian, Tao Lu
Summary: This study investigated the impact of residual chlorine on soil microbial communities. The results showed that continuous chlorine treatment did not have a lasting effect on the diversity and composition of soil microbial communities, and slightly affected the metabolic functions of rhizosphere microbial communities, which later recovered to their original status. Due to the potential slight long-term effects on plant growth and soil micro-ecology, conducting environmental risk assessments and minimizing risks to the environment are crucial.
SOIL ECOLOGY LETTERS
(2023)
