Article
Environmental Sciences
Shanshan Xu, Solrunn Hansen, Arja Rautio, Marjo-Riitta Jarvelin, Khaled Abass, Jaana Rysa, Saranya Palaniswamy, Sandra Huber, Joan O. Grimalt, Pierre Dumas, Jon Oyvind Odland
Summary: This study found lower levels of selected persistent organic pollutants (POPs) in the serum of women from Northern Norway, with concentrations of dioxins, polychlorinated biphenyls (PCBs), organochlorine pesticides (OCPs), and chlorinated paraffins showing decreasing trends over the studied period. However, medium chain chlorinated paraffins exhibited an increasing trend, raising concerns about their emerging contamination impact on humans. Further global observational studies with larger sample sizes on chlorinated paraffins are needed to validate these findings.
ENVIRONMENTAL RESEARCH
(2022)
Article
Environmental Sciences
Jakub Tomasko, Ondrej Parizek, Jana Pulkrabova
Summary: This study selected clothing as the research object because it is produced in large quantities worldwide and is worn for long periods in direct contact with human skin. Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) were found in all samples, with higher concentrations in garments with a substantial proportion of synthetic fibers. The effect of washing in the washing machine varied among individual samples.
ENVIRONMENTAL POLLUTION
(2023)
Review
Environmental Sciences
Xi Yu, Kerry Neil McPhedran, Rongfu Huang
Summary: Chlorinated paraffins (CPs) are released into the environment during production and utilization, with diet being the main exposure route for humans. Short-chain CPs (SCCPs) are more likely to be released because of their lower molecular weights, higher vapor pressures, and higher water solubilities compared to medium-chain (MCCPs) and long-chain (LCCPs) CPs. This review article discusses sample preparation and instrumental analysis methods for CPs in different types of food, such as oil, meat, and aquatic foods. It also summarizes concentrations, profiles, dietary intake, and risk assessment of CPs in food samples from various regions, highlighting the need for continuous monitoring and awareness of the potential health risks associated with increasing CPs concentrations in food worldwide.
ENVIRONMENTAL POLLUTION
(2023)
Article
Engineering, Environmental
Xueshu Li, Marco M. Hefti, Rachel F. Marek, Keri C. Hornbuckle, Kai Wang, Hans-Joachim Lehmler
Summary: This study investigated the distribution of PCBs and OH-PCBs in the human brain, finding higher levels of PCBs in adult brains and significant contributions of lower chlorinated PCBs to neurotoxicity in some donors.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2022)
Article
Environmental Sciences
J. F. Ayala-Cabrera, C. Lipok, E. Moyano, O. J. Schmitz, F. J. Santos
Summary: In this study, the performance of APCI and APPI were evaluated for the determination of PCNs in sediment samples using GC-HRMS. The comparison of the two API sources led to the selection of GC-APPI(+)-HRMS (Orbitrap) as the most effective method. The method showed great detection capabilities, low method limits of detection, and good precision and trueness for analyzing PCNs in environmental samples.
Article
Engineering, Environmental
Shuqin Liu, Xiaoji Ye, Xi Zhou, Chao Chen, Yiquan Huang, Shuting Fang, Pengran Guo, Gangfeng Ouyang
Summary: Here, we demonstrate the ability of a dual-purpose periodic mesoporous organosilica (PMO) probe to track the complex chlorinated paraffin (CP) composition in living animals. The PMO probe serves as an adsorbent-assisted atmospheric pressure chemical ionization Fourier-transform ion cyclotron resonance mass spectrometry (APCI-FT-ICR-MS) platform and an in vivo sampling device. The PMO probe enables synchronous solvent-free ionization and in-source thermal desorption of CP homologues, resulting in improved detection limits and the identification of potential CP metabolites in living fish.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Environmental Sciences
Jakub Tomasko, Michal Stupak, Denisa Parizkova, Andrea Polachova, Radim J. Sram, Jan Topinka, Jana Pulkrabova
Summary: This study is the first to report the detection of chlorinated paraffins in human blood serum in Europe, indicating exposure to these compounds with unknown effects on human health.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Article
Food Science & Technology
Thomas J. McGrath, Giulia Poma, Jasper Bombeke, Franck Limonier, Els Van Hoeck, Laure Joly, Adrian Covaci
Summary: This work optimized an analytical method for quantifying short- and medium-chained chlorinated paraffins in various food matrices, and validated the method's applicability through repeated analysis of samples fortified with SCCPs and MCCPs. The method showed good accuracy, high precision, and suitability for different food matrices.
Article
Environmental Sciences
Maykel Hernandez-Mesa, Luca Narduzzi, Sadia Ouzia, Nicolas Soetart, Laetitia Jaillardon, Yann Guitton, Bruno Le Bizec, Gaud Dervilly
Summary: Recent epidemiological studies have shown that current levels of exposure to polychlorinated biphenyls (PCBs) remain a significant health concern, especially for non-dioxin-like PCB exposure. This study used pigs as an animal model to investigate the effects of Aroclor 1260 exposure, resulting in the bioaccumulation of NDL-PCBs in pig fat and the identification of biomarkers related to PCB exposure through metabolomics and lipidomics.
Article
Engineering, Environmental
Hongyu Dang, Jessica M. Ewald, Timothy E. Mattes
Summary: This research used genome-resolved metagenomic and metatranscriptomic analyses to investigate the ecology of dehalogenating microbial communities, revealing interactions and support between Dehalococcoides and other microorganisms.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Engineering, Environmental
Chang He, Louise van Mourik, Shaoyu Tang, Phong Thai, Xianyu Wang, Sicco H. Brandsma, Pim E. G. Leonards, Kevin V. Thomas, Jochen F. Mueller
Summary: This study investigates the in vitro biotransformation of CPs by human liver fractions, which resulted in a decrease in CP concentrations. Ketones were identified as potential products of CP biotransformation, particularly for long-chain CPs. The ketone products may serve as biomarkers for CP exposure in biomonitoring studies.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Environmental Sciences
Thomas J. McGrath, Giulia Poma, Sebastien Hutinet, Yukiko Fujii, Robin E. Dodson, Boris Johnson-Restrepo, Dudsadee Muenhor, Gaud Dervilly, Ronan Cariou, Adrian Covaci
Summary: In this study, dust samples from Japan, Australia, Colombia, and Thailand were analyzed for different chain lengths of chlorinated paraffins. The results showed that chlorinated paraffins were detected in all samples, with the highest concentrations found in samples from Colombia and Thailand. Based on current toxicological data, it was determined that short-chain and medium-chain chlorinated paraffins in indoor dust do not pose a health risk through ingestion.
ENVIRONMENTAL POLLUTION
(2023)
Article
Environmental Sciences
Kamila Sredlova, Tomas Cajthaml
Summary: PCBs, despite being restricted in the 1970s, remain hazardous contaminants due to their bioaccumulative and persistent nature. Remediation of historically contaminated matrices is challenging and requires a combination of different techniques and approaches.
Article
Engineering, Environmental
Bo Yuan, Heinz Rudel, Cynthia A. de Wit, Jan Koschorreck
Summary: The study revealed the presence of various types of chlorinated paraffins in different ecosystems across Germany, with long-chain products showing higher concentrations. Data from bream samples collected downstream of a CP-manufacturing factory indicated a significant increase in concentrations of LCCPs over time, reflecting the impact of chemical regulation policies on CP production. The findings serve as an early warning of environmental concerns related to the increasing global production and use of LCCPs.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Engineering, Environmental
Moala K. Bannavti, Rachel F. Marek, Craig L. Just, Keri C. Hornbuckle
Summary: In order to reconcile federal and state regulations for PCB concentrations, the relationship between surface emissions and airborne concentrations needs to be characterized. We found that PCB emissions from flooring materials accurately predicted the magnitude and distribution of PCBs in room air.
ENVIRONMENTAL SCIENCE & TECHNOLOGY LETTERS
(2023)
Article
Biochemical Research Methods
J. F. Ayala-Cabrera, E. Moyano, F. J. Santos
JOURNAL OF CHROMATOGRAPHY A
(2020)
Article
Chemistry, Analytical
J. F. Ayala-Cabrera, A. Contreras-Llin, E. Moyano, F. J. Santos
ANALYTICA CHIMICA ACTA
(2020)
Article
Biochemical Research Methods
J. F. Ayala-Cabrera, M. abalos, E. Abad, E. Moyano, F. J. Santos
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2020)
Article
Environmental Sciences
J. F. Ayala-Cabrera, C. Lipok, E. Moyano, O. J. Schmitz, F. J. Santos
Summary: In this study, the performance of APCI and APPI were evaluated for the determination of PCNs in sediment samples using GC-HRMS. The comparison of the two API sources led to the selection of GC-APPI(+)-HRMS (Orbitrap) as the most effective method. The method showed great detection capabilities, low method limits of detection, and good precision and trueness for analyzing PCNs in environmental samples.
Article
Biochemical Research Methods
J. F. Ayala-Cabrera, C. Lipok, J. Li, E. Moyano, O. J. Schmitz, F. J. Santos
Summary: The study evaluated the performance of comprehensive two-dimensional gas chromatography coupled to mass spectrometry (GCxGC-MS) for the separation of polychlorinated naphthalenes (PCNs), achieving efficient separation and surpassing traditional gas chromatography methods.
JOURNAL OF CHROMATOGRAPHY A
(2021)
Article
Food Science & Technology
Ane Arrizabalaga-Larranaga, Guillem Campmajo, Javier Saurina, Oscar Nunez, Francisco Javier Santos, Encarnacion Moyano
Summary: The study used the UHPLC-APCI-HRMS method for the geographical origin authentication of paprika based on capsaicinoids and carotenoids determination, achieving an authentication rate of 80.9%.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Chemistry, Analytical
Juan F. Ayala-Cabrera, F. Javier Santos, Encarnacion Moyano
Summary: This review article focuses on the latest advances in analytical methodologies for the determination of halogenated organic contaminants, highlighting future prospects for improving analytical determinations of these compounds and the throughput of environmental control laboratories in this field.
TRENDS IN ENVIRONMENTAL ANALYTICAL CHEMISTRY
(2021)
Article
Biochemical Research Methods
Juan F. Ayala-Cabrera, Silvia Lacorte, Encarnacion Moyano, Francisco Javier Santos
Summary: A new analytical method was developed for the selective determination of Dechlorane Plus and related compounds in gull egg samples, showing high selectivity and sensitivity for complex environmental samples. The results demonstrated significant differences in the concentration profiles of Dechlorane Plus in eggs from different gull breeding locations and between gull species of the same protected area. This study highlights the performance of the GC-APPI-HRMS system for the analysis of Dechlorane Plus and related compounds.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Chemistry, Analytical
J. F. Ayala-Cabrera, M. T. Galceran, E. Moyano, F. J. Santos
Summary: A new GC-HRMS method based on APPI was developed for the accurate determination of SCCPs, achieving efficient ionisation and selective determination by monitoring [M+Cl](-) adduct ions. This method offers advantages such as quantification of individual congener groups and simplification of calibration method, making it a reliable alternative for determining SCCPs in environmental samples.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Analytical
A. Arrizabalaga-Larranaga, S. Epigmenio-Chamu, F. J. Santos, E. Moyano
Summary: This paper describes the development of a rapid and sensitive method for detecting banned dyes in spice samples using UHPLC-MS/MS technology combined with three atmospheric pressure ionization sources. The proposed method demonstrated good performance in sample analysis, with low detection limits, good precision, and accurate quantitation.
ANALYTICA CHIMICA ACTA
(2021)
Article
Environmental Sciences
Pere Colomer-Vidal, Albert Bertolero, Carles Alcaraz, Elba Garreta-Lara, Francisco Javier Santos, Silvia Lacorte
Summary: The study evaluated the geographical distribution and 10-year temporal trends of 17 PFAS in eggs of two gull species from 5 main Spanish colonies. PFOS was the predominant compound in all samples, with varying concentrations and patterns observed among different colonies. The study highlights the importance of continuous long-term monitoring using gull eggs as bioindicators of environmental pollution.
ENVIRONMENTAL POLLUTION
(2022)
Article
Chemistry, Analytical
R. Sero, J. F. Ayala-Cabrera, F. J. Santos, E. Moyano
Summary: In this work, the combination of paper spray and atmospheric pressure photoionization-mass spectrometry (PS-APPI-MS) was used for the determination of non-polar and low polar compounds. The method demonstrated good performance in the analysis of fluorotelomer alcohols, fluoroctanesulfonamides, and fluorooctane sulfonamido-ethanols, with the ability to detect these compounds at low levels. The PS-APPI-HRMS method allows for fast screening and quantitation of target compounds in waterproof impregnation sprays, providing a cost-effective and efficient approach for routine laboratories.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biochemical Research Methods
Ane Arrizabalaga-Larranaga, Pedro de Juan-de Juan, Claudia Bressan, Mercedes Vazquez-Espinosa, Ana Gonzalez-de-Peredo, F. Javier Santos, Encarnacion Moyano
Summary: This study developed a sensitive and selective UHPLC-MS/MS method for the detection of 23 PAAs, showing the advantage of APCI as an alternative method for the analysis of PAAs. The developed method was applied to the analysis of kitchenware samples, where PAAs concentrations above the legislated limit were detected in 18 out of 20 samples.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Noemi Inmaculada Medina-Perez, Francisco Javier Santos, Elisa Berdalet, Encarnacion Moyano
Summary: This study explores the challenges faced in quantifying analogues of palytoxin (PLTX) using ultra-high-performance liquid chromatography high-resolution mass spectrometry-based techniques. The research focuses on the mass spectra of PLTX analogues and evaluates different instrument conditions and extraction protocols to develop a more reliable and robust quantification method. The proposed method is applied to quantify OVTXs (-a to -g) and iso-PLTX during a 2019 Ostreopsis cf. ovata bloom.
ANALYTICAL METHODS
(2023)
Proceedings Paper
Education & Educational Research
Ane Arrizabalaga-Larranaga, Guillem Campmajo, Juan F. Ayala-Cabrera, Raquel Sero, F. Javier Santos, Encarna Moyano, Oscar Nunez
14TH INTERNATIONAL TECHNOLOGY, EDUCATION AND DEVELOPMENT CONFERENCE (INTED2020)
(2020)