Understanding the Guanidine-Like Cationic Moiety for Optimal Binding into the DNA Minor Groove

Binding studies of a large antiviral polyamide to a natural HPV sequence

(2014) Gaofei He et al.   BIOCHIMIE

In and out of the minor groove: interaction of an AT-rich DNA with the drug CD27

(2014) Francisco J. Acosta-Reyes et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Oligoamides of 2-amino-5-alkylthiazole 4-carboxylic acids: anti-trypanosomal compounds

(2013) Stuart Lang et al.   MEDICINAL CHEMISTRY RESEARCH

Minor groove binders as anti-infective agents

(2013) Michael P. Barrett et al.   PHARMACOLOGY & THERAPEUTICS

Exceptionally strong intermolecular association in hydrophobic DNA minor groove binders and their potential therapeutic consequences

(2013) John A. Parkinson et al.   MedChemComm

Water-Mediated Binding of Agents that Target the DNA Minor Groove

(2011) Yang Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

New Insight into the Molecular Mechanisms of the Biological Effects of DNA Minor Groove Binders

(2011) Xinbo Zhang et al.   PLoS One

Understanding the DNA binding of novel non-symmetrical guanidinium/2-aminoimidazolinium derivatives

(2010) Padraic S. Nagle et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Crystal Structure of a Trypanocidal 4,4′-Bis(imidazolinylamino)diphenylamine Bound to DNA,

(2009) LaTeca S. Glass et al.   BIOCHEMISTRY

DNA minor groove binders: Back in the groove

(2009) Xuemei Cai et al.   CANCER TREATMENT REVIEWS

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

(2009) Garrett M. Morris et al.   JOURNAL OF COMPUTATIONAL CHEMISTRY

Asymmetrical Diaromatic Guanidinium/2-Aminoimidazolinium Derivatives: Synthesis and DNA Affinity

(2009) Padraic S. Nagle et al.   JOURNAL OF MEDICINAL CHEMISTRY

A new synthesis of alkene-containing minor-groove binders and essential hydrogen bonding in binding to DNA and in antibacterial activity

(2009) Nahoum G. Anthony et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Facile and Convenient Method of Deuterium Gas Generation Using a Pd/C-Catalyzed H2–D2 Exchange Reaction and Its Application to Synthesis of Deuterium-Labeled Compounds

(2008) Takanori Kurita et al.   CHEMISTRY-A EUROPEAN JOURNAL

Novel linear triaryl guanidines, N-substituted guanidines and potential prodrugs as antiprotozoal agents

(2008) Reem K. Arafa et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Guanidine and 2-Aminoimidazoline Aromatic Derivatives as α2-Adrenoceptor Antagonists. 2. Exploring Alkyl Linkers for New Antidepressants

(2008) Fernando Rodriguez et al.   JOURNAL OF MEDICINAL CHEMISTRY

New Bis(2-aminoimidazoline) and Bisguanidine DNA Minor Groove Binders with Potent in Vivo Antitrypanosomal and Antiplasmodial Activity

(2008) Fernando Rodríguez et al.   JOURNAL OF MEDICINAL CHEMISTRY