Sigma-2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity

Dynamic Interaction between Sigma-1 Receptor and Kv1.2 Shapes Neuronal and Behavioral Responses to Cocaine

(2013) Saïd Kourrich et al.   CELL

Sigma receptor modulators: a patent review

(2013) Simona Collina et al.   EXPERT OPINION ON THERAPEUTIC PATENTS

Sigma-2 ligands induce tumour cell death by multiple signalling pathways

(2012) C Zeng et al.   BRITISH JOURNAL OF CANCER

2-Aminopyridine Derivatives as Potential σ2Receptor Antagonists

(2012) Carmen Abate et al.   ChemMedChem

Classes of Sigma2 (σ2) Receptor Ligands: Structure Affinity Relationship (SAfiR) Studies and Antiproliferative Activity

(2012) Carmen Abate et al.   CURRENT PHARMACEUTICAL DESIGN

Collateral sensitivity as a strategy against cancer multidrug resistance

(2012) Kristen M. Pluchino et al.   DRUG RESISTANCE UPDATES

The sigma-1 receptor: roles in neuronal plasticity and disease

(2012) Saïd Kourrich et al.   TRENDS IN NEUROSCIENCES

Synthesis and pharmacological evaluation of indole-based sigma receptor ligands

(2011) Christophe Mésangeau et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers

(2011) Carmen Abate et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Analogues of σ Receptor Ligand 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28) with Added Polar Functionality and Reduced Lipophilicity for Potential Use as Positron Emission Tomography Radiotracers

(2011) Carmen Abate et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and Structure–Activity Evaluation of Isatin-β-thiosemicarbazones with Improved Selective Activity toward Multidrug-Resistant Cells Expressing P-Glycoprotein

(2011) Matthew D. Hall et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of the PGRMC1 protein complex as the putative sigma-2 receptor binding site

(2011) Jinbin Xu et al.   Nature Communications

1-Cyclohexyl-4-(4-arylcyclohexyl)piperazines: Mixed σ and Human Δ8-Δ7 Sterol Isomerase Ligands with Antiproliferative and P-Glycoprotein Inhibitory Activity

(2010) Carmen Abate et al.   ChemMedChem

F281, synthetic agonist of the sigma-2 receptor, induces Ca2+ efflux from the endoplasmic reticulum and mitochondria in SK-N-SH cells

(2009) Giuseppe Cassano et al.   CELL CALCIUM

Multi-Drug-Resistance-Reverting Agents: 2-Aryloxazole and 2-Arylthiazole Derivatives as Potent BCRP or MRP1 Inhibitors

(2009) Nicola A. Colabufo et al.   ChemMedChem

Pharmacology and Therapeutic Potential of Sigma1 Receptor Ligands

(2009) E. Cobos et al.   Current Neuropharmacology

Exploring the Importance of Piperazine N-Atoms for σ2Receptor Affinity and Activity in a Series of Analogs of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydronaphthalen-1-yl)propyl]piperazine (PB28)†

(2009) Francesco Berardi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Substituted benzylaminoalkylindoles with preference for the σ2 binding site

(2007) Maria Grazia Mamolo et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY