Kinetic Template-Guided Tethering of Fragments

Experiences in fragment-based drug discovery

(2012) Christopher W. Murray et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Superiority of a novel EGFR targeted covalent inhibitor over its reversible counterpart in overcoming drug resistance

(2012) Juswinder Singh et al.   MedChemComm

Discovery of a potent and highly selective PDK1 inhibitor via fragment-based drug discovery

(2011) Daniel A. Erlanson et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The resurgence of covalent drugs

(2011) Juswinder Singh et al.   NATURE REVIEWS DRUG DISCOVERY

Drugging challenging targets using fragment-based approaches

(2010) Anthony G Coyne et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Targeted covalent drugs of the kinase family

(2010) Juswinder Singh et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Covalent Capture: Merging Covalent and Noncovalent Synthesis

(2009) Leonard J. Prins et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent progress in fragment-based lead discovery

(2009) Michèle N Schulz et al.   CURRENT OPINION IN PHARMACOLOGY

Covalent Modifiers: An Orthogonal Approach to Drug Design

(2009) Michele H. Potashman et al.   JOURNAL OF MEDICINAL CHEMISTRY

The rise of fragment-based drug discovery

(2009) Christopher W. Murray et al.   Nature Chemistry

Discovery of an Aurora kinase inhibitor through site-specific dynamic combinatorial chemistry

(2008) Mark T. Cancilla et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS