Discovery and Development of Thiazolo[3,2-a]pyrimidinone Derivatives as General Inhibitors of Bcl-2 Family Proteins

BI-97C1, an Optically Pure Apogossypol Derivative as Pan-Active Inhibitor of Antiapoptotic B-Cell Lymphoma/Leukemia-2 (Bcl-2) Family Proteins

(2010) Jun Wei et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development of Novel Thiazolopyrimidines as CDC25B Phosphatase Inhibitors

(2009) Stéphanie Kolb et al.   ChemMedChem

ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor

(2008) C. Tse et al.   CANCER RESEARCH

Acylpyrogallols as Inhibitors of Antiapoptotic Bcl-2 Proteins

(2008) Guozhi Tang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery of Incednine as a Potent Modulator of the Anti-apoptotic Function of Bcl-xL from Microbial Origin

(2008) Yushi Futamura et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

BCL-2 family antagonists for cancer therapy

(2008) Guillaume Lessene et al.   NATURE REVIEWS DRUG DISCOVERY