Identification of 1,3-Diiminoisoindoline Carbohydrazides as Potential Antimalarial Candidates

From Conventional to Unusual Enzyme Inhibitor Scaffolds: The Quest for Target Specificity

(2011) Eric Meggers   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Inhibitors of the Herbicidal Target IspD: Allosteric Site Binding

(2011) Matthias C. Witschel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Feeding the Antimalarial Pipeline

(2010) Martin Schlitzer et al.   ChemMedChem

Thousands of chemical starting points for antimalarial lead identification

(2010) Francisco-Javier Gamo et al.   NATURE

Chemical genetics of Plasmodium falciparum

(2010) W. Armand Guiguemde et al.   NATURE

Is the Tide Turning for New Malaria Medicines?

(2010) T. N. C. Wells   SCIENCE

Spiroindolones, a Potent Compound Class for the Treatment of Malaria

(2010) M. Rottmann et al.   SCIENCE

Artemisinin Resistance inPlasmodium falciparumMalaria

(2009) Arjen M. Dondorp et al.   NEW ENGLAND JOURNAL OF MEDICINE

Inhibitors of the kinase IspE: structure–activity relationships and co-crystal structure analysis

(2008) Anna K. H. Hirsch et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Physiological function of IspE, a plastid MEP pathway gene for isoprenoid biosynthesis, in organelle biogenesis and cell morphogenesis in Nicotiana benthamiana

(2008) Chang Sook Ahn et al.   PLANT MOLECULAR BIOLOGY

In silicoactivity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

(2008) David Plouffe et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA