Screening for the Drug-Phospholipid Interaction: Correlation to Phospholipidosis

Phospholipidosis Assay in HepG2 Cells and Rat or Rhesus Hepatocytes Using Phospholipid Probe NBD-PE

(2008) Neetesh Bhandari et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Anionic Phospholipids Affect the Rate and Extent of Flux through the Mechanosensitive Channel of Large Conductance MscL†

(2008) Andrew M. Powl et al.   BIOCHEMISTRY

Protein modulation of lipids, and vice-versa, in membranes

(2008) Derek Marsh   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Membrane Hydrocarbon Thickness Modulates the Dynamics of a Membrane Transport Protein

(2008) Qi Xu et al.   BIOPHYSICAL JOURNAL

Cardiolipin, the heart of mitochondrial metabolism

(2008) R. H. Houtkooper et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Structure and dynamics of polyunsaturated hydrocarbon chains in lipid bilayers—significance for GPCR function

(2008) Klaus Gawrisch et al.   CHEMISTRY AND PHYSICS OF LIPIDS

Quantitative modeling of selective lysosomal targeting for drug design

(2008) Stefan Trapp et al.   EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS

Drug-induced liver injury through mitochondrial dysfunction: mechanisms and detection during preclinical safety studies

(2008) Gilles Labbe et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels

(2008) Julien Chevallier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modification of membrane heterogeneity by antipsychotic drugs: An X-ray diffraction comparative study

(2008) Cedric Tessier et al.   JOURNAL OF COLLOID AND INTERFACE SCIENCE

Assessment of Drug−Lipid Complex Formation by a High-Throughput Langmuir-Balance and Correlation to Phospholipidosis

(2008) Pavol Vitovič et al.   JOURNAL OF MEDICINAL CHEMISTRY

Accumulation of bis(monoacylglycero)phosphate and gangliosides in mouse models of neuronal ceroid lipofuscinosis

(2008) Sabrina Jabs et al.   JOURNAL OF NEUROCHEMISTRY

COSMOmic: A Mechanistic Approach to the Calculation of Membrane−Water Partition Coefficients and Internal Distributions within Membranes and Micelles

(2008) Andreas Klamt et al.   JOURNAL OF PHYSICAL CHEMISTRY B

High-Affinity Small Molecule−Phospholipid Complex Formation: Binding of Siramesine to Phosphatidic Acid

(2008) Mikko J. Parry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantiospecific Interactions between Cholesterol and Phospholipids

(2008) Juha-Matti Alakoskela et al.   LANGMUIR

Protein Networks Supporting AP-3 Function in Targeting Lysosomal Membrane Proteins

(2008) Thorsten Baust et al.   MOLECULAR BIOLOGY OF THE CELL

Removal of phospho-head groups of membrane lipids immobilizes voltage sensors of K+ channels

(2008) Yanping Xu et al.   NATURE

Embedded cholesterol in the nicotinic acetylcholine receptor

(2008) G. Brannigan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Development of a Phospholipidosis Database and Predictive Quantitative Structure-Activity Relationship (QSAR) Models

(2008) Naomi L. Kruhlak et al.   TOXICOLOGY MECHANISMS AND METHODS

Drug-induced Phospholipidosis -Pathological Aspects and Its Prediction

(2008) Takashi Nonoyama et al.   Journal of Toxicologic Pathology