Enantioselective Synthesis of Quaternary Carbon Stereocenters: Addition of 3-Substituted Oxindoles to Vinyl Sulfone Catalyzed by Pentanidiums

Catalytic Enantioselective Alkylation of Sulfenate Anions to Chiral Heterocyclic Sulfoxides Using Halogenated Pentanidium Salts

(2014) Lili Zong et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Asymmetric Synthesis of 3,3′-Diaryloxindoles as Triarylmethanes with a Chiral All-Carbon Quaternary Center: Phase-Transfer-Catalyzed SNAr Reaction

(2014) Seiji Shirakawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic enantioselective synthesis of quaternary carbon stereocentres

(2014) Kyle W. Quasdorf et al.   NATURE

Enantioselective construction of remote quaternary stereocentres

(2014) Tian-Sheng Mei et al.   NATURE

Asymmetric phase-transfer reactions under base-free neutral conditions

(2014) Seiji Shirakawa et al.   TETRAHEDRON LETTERS

Peptidomimetic organocatalysts: efficient Michael addition of ketones onto nitroolefins with very low catalyst loading

(2014) Srivari Chandrasekhar et al.   RSC Advances

Unusual Acetylation-Dependent Reaction Cascade in the Biosynthesis of the Pyrroloindole Drug Physostigmine

(2013) Joyce Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Methylene-Bridged Bis(imidazoline)-Derived 2-Oxopyrimidinium Salts as Catalysts for Asymmetric Michael Reactions

(2013) Andrey E. Sheshenev et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic Enantioselective Michael Addition of α-Aryl-α-Isocyanoacetates to Vinyl Selenone: Synthesis of α,α-Disubstituted α-Amino Acids and (+)- and (−)-Trigonoliimine A

(2013) Thomas Buyck et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Developments in Asymmetric Phase-Transfer Reactions

(2013) Seiji Shirakawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bicyclic guanidinium-catalyzed enantioselective phase-transfer alkylation: direct access to pyrroloindolines and furoindolines

(2013) Wenchao Chen et al.   CHEMICAL COMMUNICATIONS

Efficient Enantioselective Total Synthesis of (−)-Horsfiline

(2013) Suckchang Hong et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Michael Addition of Malonates to Isatylidene-3-acetaldehydes: Application to the Total Synthesis of (−)-Debromoflustramine E

(2013) Renrong Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Bicyclic-Guanidine-Catalyzed Asymmetric Michael Addition of 3-Substituted Oxindoles to 2-Cyclopentenone

(2013) Caiyun Yang et al.   Chemistry-An Asian Journal

Rapid Access to Spirocyclic Oxindole Alkaloids: Application of the Asymmetric Palladium-Catalyzed [3 + 2] Trimethylenemethane Cycloaddition

(2013) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective synthesis of spirocyclic oxindoles based on a one-pot Ullmann coupling/Claisen rearrangement and its application to the synthesis of a hexahydropyrrolo[2,3-b]indole alkaloid

(2013) Hiroshi Miyamoto et al.   TETRAHEDRON

Asymmetric Ion-Pairing Catalysis

(2012) Katrien Brak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent advances in organocatalytic methods for the synthesis of disubstituted 2- and 3-indolinones

(2012) Renato Dalpozzo et al.   CHEMICAL SOCIETY REVIEWS

Catalytic and Enantioselective α-Functionalization of Oxindoles Through Oxidative Reactions with Naphthoquinones

(2012) Woon-Yew Siau et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Michael Addition of 3-Aryl-Substituted Oxindoles to Methyl Vinyl Ketone Catalyzed by a Binaphthyl-Modified Bifunctional Organocatalyst

(2012) Hyun Joo Lee et al.   MOLECULES

The progression of chiral anions from concepts to applications in asymmetric catalysis

(2012) Robert J. Phipps et al.   Nature Chemistry

Pentanidium–Catalyzed Enantioselective α-Hydroxylation of Oxindoles Using Molecular Oxygen

(2012) Yuanyong Yang et al.   ORGANIC LETTERS

Squaramide-catalyzed diastereo- and enantioselective Michael addition of 3-substituted oxindoles to nitroalkenes

(2012) Wen Yang et al.   TETRAHEDRON-ASYMMETRY

Organocatalytic Enantioselective Decarboxylative Addition of Malonic Acids Half Thioesters to Isatins

(2011) Noriyuki Hara et al.   ADVANCED SYNTHESIS & CATALYSIS

Total Synthesis Guided Structure Elucidation of (+)-Psychotetramine

(2011) Klement Foo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Neutral Amination of Nitroolefins Catalyzed by Chiral Bifunctional Ammonium Salts in Water-Rich Biphasic Solvent

(2011) Lijia Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Direction of Kinetically versus Thermodynamically Controlled Organocatalysis and Its Application in Chemoenzymatic Synthesis

(2011) Giuseppe Rulli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Organocatalytic 1,6-Conjugate Addition of Aldehydes to Dienic Sulfones

(2011) John J. Murphy et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Core-Structure-Oriented Asymmetric Organocatalytic Substitution of 3-Hydroxyoxindoles: Application in the Enantioselective Total Synthesis of (+)-Folicanthine

(2011) Chang Guo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly enantioselective Michael addition of 2-oxindoles to vinyl selenone in RTILs catalyzed by a Cinchona alkaloid-based thiourea

(2011) Tao Zhang et al.   CHEMICAL COMMUNICATIONS

Low-loading asymmetric organocatalysis

(2011) Francesco Giacalone et al.   CHEMICAL SOCIETY REVIEWS

Structure, Bioactivity and Synthesis of Natural Products with Hexahydropyrrolo[2,3-b]indole

(2011) Pau Ruiz-Sanchis et al.   CHEMISTRY-A EUROPEAN JOURNAL

Highly Enantioselective Michael Addition of 3-Aryloxindoles to Phenyl Vinyl Sulfone Catalyzed by Cinchona Alkaloid-Derived Bifunctional Amine-Thiourea Catalysts Bearing Sulfonamide as Multiple Hydrogen-Bonding Donors

(2011) Mei-Xin Zhao et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Amino-Indanol-Catalyzed Asymmetric Michael Additions of Oxindoles to Protected 2-Amino-1-nitroethenes for the Synthesis of 3,3′-Disubstituted Oxindoles Bearing α,β-Diamino Functionality

(2011) Xiong-Li Liu et al.   JOURNAL OF ORGANIC CHEMISTRY

Pentanidium-Catalyzed Enantioselective Phase-Transfer Conjugate Addition Reactions

(2011) Ting Ma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exercising Regiocontrol in Palladium-Catalyzed Asymmetric Prenylations and Geranylation: Unifying Strategy toward Flustramines A and B

(2011) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chiral 1,2,3-Triazoliums as New Cationic Organic Catalysts with Anion-Recognition Ability: Application to Asymmetric Alkylation of Oxindoles

(2011) Kohsuke Ohmatsu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Collective synthesis of natural products by means of organocascade catalysis

(2011) Spencer B. Jones et al.   NATURE

A New Class of Structurally Rigid Tricyclic Chiral Secondary Amine Organocatalyst: Highly Enantioselective Organocatalytic Michael Addition of Aldehydes to Vinyl Sulfones

(2011) Jian Xiao et al.   ORGANIC LETTERS

Cinchona alkaloid-based phosphoramide catalyzed highly enantioselective Michael addition of unprotected 3-substituted oxindoles to nitroolefins

(2011) Miao Ding et al.   Chemical Science

Catalytic Asymmetric Synthesis of Oxindoles Bearing a Tetrasubstituted Stereocenter at the C-3 Position

(2010) Feng Zhou et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Michael Addition Reaction of 3-Substituted Oxindoles to Nitroolefins Catalyzed by a Chiral Alkyl- Substituted Thiourea Catalyst

(2010) Xin Li et al.   ADVANCED SYNTHESIS & CATALYSIS

Asymmetric Organocatalysis with Sulfones

(2010) Martin Nielsen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Stereocontrolled Creation of All-Carbon Quaternary Stereocenters by Organocatalytic Conjugate Addition of Oxindoles to Vinyl Sulfone

(2010) Qiang Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral primary amine mediated conjugate addition of branched aldehydes to vinyl sulfone: asymmetric generation of quaternary carbon centers

(2010) Qiang Zhu et al.   CHEMICAL COMMUNICATIONS

Palladium-Catalyzed Enantioselective Ene and Aldol Reactions with Isatins, Keto Esters, and Diketones: Reliable Approach to Chiral Tertiary Alcohols

(2010) Kohsuke Aikawa et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Palladium-Catalyzed Asymmetric Benzylation of 3-Aryl Oxindoles

(2010) Barry M. Trost et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Stereoablative Alkylation of 3-Halooxindoles: Facile Access to Oxindoles with C3 All-Carbon Quaternary Stereocenters

(2009) Sandy Ma et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Phosphonium Salts as Chiral Phase-Transfer Catalysts: Asymmetric Michael and Mannich Reactions of 3-Aryloxindoles

(2009) Rongjun He et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Chiral Amine-Mediated Asymmetric Conjugate Additions to Vinyl Sulfones

(2009) Qiang Zhu et al.   AUSTRALIAN JOURNAL OF CHEMISTRY

Asymmetric Iminium Ion Catalysis with a Novel Bifunctional Primary Amine Thiourea: Controlling Adjacent Quaternary and Tertiary Stereocenters

(2009) Patrizia Galzerano et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Organocatalytic Conjugate Addition of Aldehydes to Vinyl Sulfones and Vinyl Phosphonates as Challenging Michael Acceptors

(2009) Sarah Sulzer-Mossé et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Base-Free Phase-Transfer Reaction in Water-Rich Solvent

(2009) Rongjun He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thiourea-Catalyzed Highly Enantio- and Diastereoselective Additions of Oxindoles to Nitroolefins: Application to the Formal Synthesis of (+)-Physostigmine

(2009) Tommy Bui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Michael addition reaction of 3-substituted-N-Boc oxindoles to activated terminal alkenes catalyzed by a bifunctional tertiary-amine thiourea catalyst

(2009) Xin Li et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enantioselective Conjugate Addition of Nitroalkanes to Vinyl Sulfone: An Organocatalytic Access to Chiral Amines

(2009) Qiang Zhu et al.   ORGANIC LETTERS

Asymmetric Syntheses of Oxindole and Indole Spirocyclic Alkaloid Natural Products

(2009) Barry Trost et al.   SYNTHESIS-STUTTGART

A novel and efficient total synthesis of (±)-physostigmine

(2009) Mukund G. Kulkarni et al.   TETRAHEDRON LETTERS

Asymmetric organocatalytic Michael addition of ketones to vinyl sulfone

(2008) Qiang Zhu et al.   CHEMICAL COMMUNICATIONS