Enantioselective Synthesis and Physicochemical Properties of Libraries of 3-Amino- and 3-Amidofluoropiperidines

β-Secretase (BACE1) Inhibitors with High in Vivo Efficacy Suitable for Clinical Evaluation in Alzheimer’s Disease

(2013) Hans Hilpert et al.   JOURNAL OF MEDICINAL CHEMISTRY

Predicting the physicochemical profile of diastereoisomeric histidine-containing dipeptides by property space analysis

(2012) Giulio Vistoli et al.   CHIRALITY

Large, chemically diverse dataset of logP measurements for benchmarking studies

(2012) Sophie Martel et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

3-Amido Pyrrolopyrazine JAK Kinase Inhibitors: Development of a JAK3 vs JAK1 Selective Inhibitor and Evaluation in Cellular and in Vivo Models

(2012) Michael Soth et al.   JOURNAL OF MEDICINAL CHEMISTRY

Ring Expansion of Cyclic β-Amino Alcohols Induced by Diethylaminosulfur Trifluoride: Synthesis of Cyclic Amines with a Tertiary Fluorine at C3

(2012) Bruno Anxionnat et al.   JOURNAL OF ORGANIC CHEMISTRY

Predicting the pKa of Small Molecules

(2011) Matthias Rupp et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Synthesis and in vitro antimycobacterial activity of balofloxacin ethylene isatin derivatives

(2010) Lian-Shun Feng et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

In vivo antibacterial activity of nemonoxacin, a novel non-fluorinated quinolone

(2010) C.-R. Li et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Evaluation of pKaEstimation Methods on 211 Druglike Compounds

(2010) John Manchester et al.   Journal of Chemical Information and Modeling

Predicting pKa

(2009) Adam C. Lee et al.   Journal of Chemical Information and Modeling

Comparison of Nine Programs Predicting pKaValues of Pharmaceutical Substances

(2009) Chenzhong Liao et al.   Journal of Chemical Information and Modeling

Comparative Evaluation of in Silico pKaPrediction Tools on the Gold Standard Dataset

(2009) György T. Balogh et al.   Quantitative structure-activity relationships & combinatorial science

The Many Roles for Fluorine in Medicinal Chemistry

(2008) William K. Hagmann   JOURNAL OF MEDICINAL CHEMISTRY

Calculation of Molecular Lipophilicity: State-of-the-Art and Comparison of LogP Methods on more than 96,000 Compounds

(2008) Raimund Mannhold et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Chemistry and Biology of the Aeruginosin Family of Serine Protease Inhibitors

(2007) Karolina Ersmark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fluorine in medicinal chemistry

(2007) Sophie Purser et al.   CHEMICAL SOCIETY REVIEWS