Article
Biochemistry & Molecular Biology
Carolina Nunes da Silva, Kenia Nunes Pedrosa, Grazielle Caroline da Silva, Pricila da Silva Cunha, Thiago F. Diniz, Luisa Michette S. Maia, Flavia De Marco Almeida, Ricardo Santiago Gomez, Virginia S. Lemos, Dawidson Assis Gomes, Maria Elena de Lima
Summary: PnPP-19 peptide potentiates erectile function through nitric oxide activation, with a key role of endothelial nitric oxide synthase, and inducible nitric oxide synthase enhancing its effect on erectile function.
NITRIC OXIDE-BIOLOGY AND CHEMISTRY
(2021)
Article
Electrochemistry
P. Arul, Sheng-Tung Huang, Veerappan Mani, Yi-Chiuen Hu
Summary: The study presents a method for quantitative determination of NO2- and NO using Bi-MOF intercalated carbon nanofibers. The composite exhibited excellent electrocatalytic activity and wide linear range, with LODs of 0.184 nM and 3.463 nM for NO2- and NO, respectively, allowing for quantitative determination of nitro hazards in environmental effluent and tap water samples.
ELECTROCHIMICA ACTA
(2021)
Article
Chemistry, Applied
Nutchapong Suwanwong, Jaruwan Chatwichien, Kittipong Chainok, Somsak Ruchirawat, Siwarutt Boonyarattanakalin
Summary: Enhancing local nitric oxide concentration is crucial for adjuvants and immune responses. Studying the structure of LAM glycan motifs on Mycobacterium tuberculosis can provide valuable information for vaccine development.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Analytical
Jaysiva Ganesamurthi, Ragurethinam Shanmugam, Shen-Ming Chen, Pitchaimani Veerakumar
Summary: In this study, a new electrode material Bi2S3/Zn-GCN was developed and demonstrated excellent electrochemical performance for NO sensing. The electrochemical analysis showed that the composite material has a very low detection limit and high sensitivity. The experimental results suggest that the sensor has potential applications in detecting NO in different samples.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Materials Science, Multidisciplinary
M. Cumbul Altay, S. Eroglu
Summary: The study investigated the reduction behavior of Bi2O3 in the gaseous atmosphere generated by the pyrolysis of waste tires, finding that the addition of a minor amount of waste high-density polyethylene at high temperatures can achieve full reduction of Bi2O3.
Review
Biotechnology & Applied Microbiology
Yu-Ming Cai, Ying-Dan Zhang, Liang Yang
Summary: Nitric oxide (NO) plays a crucial role in controlling microbial infections, particularly in chronic lung infections. While endogenously generated NO helps eradicate invading pathogens in healthy individuals, this pathway is often compromised in patients with chronic lung infections. Exogenous NO supplementation may improve therapeutic outcomes in these cases.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2021)
Article
Soil Science
Yajun Geng, Jinyang Wang, Zhirong Sun, Cheng Ji, Mengyuan Huang, Yihe Zhang, Pinshang Xu, Shuqing Li, Mark Pawlett, Jianwen Zou
Summary: The study showed that organic and bio-organic fertilizers can reduce soil nitrogen oxide emissions and increase crop yield compared to chemical fertilizer. Bio-organic fertilizer was found to be the most effective in mitigating nitrogen losses.
Article
Multidisciplinary Sciences
Hongyuan Zhang, Zhiqiang Zhao, Shengnan Sun, Sen Zhang, Yuequan Wang, Xuanbo Zhang, Jin Sun, Zhonggui He, Shenwu Zhang, Cong Luo
Summary: In this study, the authors developed a self-propelling nano-penetrator assembled with a photothermal photosensitizer and a photothermal-activable NO donor. The nano-penetrator showed advantages in terms of NO productivity and autonomous motion under laser irradiation. In animal models, it successfully navigated to thrombus, penetrated deep into the clot, and achieved effective thrombolysis and prevention of thrombosis recurrence and ischemic stroke.
NATURE COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Kehinde D. Jayeola, Dimpo S. Sipuka, Tsholofelo I. Sebokolodi, Oluchi V. . Nkwachukwu, Charles Muzenda, Babatunde A. Koiki, Jonathan O. Babalola, Minghua Zhou, Omotayo A. Arotiba
Summary: In this paper, a Z-scheme heterojunction of Bi2O2S and ZnO nanoparticles was prepared for the removal of ciprofloxacin from wastewater. The heterojunction showed enhanced degradation performance compared to individual Bi2O2S and ZnO photoanodes, attributed to the presence of an internal electric field, low recombination rate of photogenerated electrons and holes, lower charge transfer resistance, and high photocurrent density. The performance of the heterojunction was characterized and analyzed through various techniques, and it was found to be stable after several treatment cycles. The paper demonstrates the potential of Z scheme band gap engineering of semiconductors for pharmaceutical removal in wastewater.
CHEMICAL ENGINEERING JOURNAL
(2024)
Review
Materials Science, Multidisciplinary
Kinshuk Malik, Shruti Sharma, Malti Sharma, Sharda Mahilkar Sonkar, Ayushi Mishra, Lajpreet Kaur, Himanshu Ojha, Mallika Pathak
Summary: In this review, the synthetic strategies and applications of carbon supported copper nanomaterials are discussed. The use of these materials as catalysts and their potential in various applications are explored.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Engineering, Environmental
Yunpei Cui, Teng Wang, Jiayou Liu, Lizhen Hu, Qianqian Nie, Zhongchao Tan, Hesheng Yu
Summary: Composite materials (GQDs/BWO) were prepared by combining graphene quantum dots (GQDs) with bismuth tungstate (Bi2WO6) to enhance photocatalytic degradation of nitric oxide. The introduction of GQDs in the composite catalyst significantly improved the photocatalytic performance, attributed to enhanced electron-hole separation efficiency and inhibition of recombination, resulting from increased surface area and light absorption.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Engineering, Chemical
Xuelei Xu, Yi Wang, Dun Zhang
Summary: A recycled photocatalyst film of epoxy resin induced hydrothermal in-situ growth Z-scheme bismuth oxide/bismuth oxyiodide heterostructure was constructed on various metals. The film efficiently removed contaminants and microorganisms from waterbody under visible light illumination, showing great potential for broad applications.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Engineering, Environmental
Seung-Woon Baek, Da-Seul Kim, Jun-Kyu Lee, Jun Hyuk Kim, Semi Lee, Jeong Min Park, So-Yeon Park, Duck Hyun Song, Chun Gwon Park, Dong Keun Han
Summary: A novel nanoparticle with enhanced nitric oxide (NO) generating ability was synthesized to improve the biodegradable vascular scaffold (BVS) intervention for coronary artery diseases. The BVS containing the synthesized nanoparticles demonstrated potent functional recovery ability of unhealthy vessels by inhibiting platelet adhesion and activation, increasing endothelial cell proliferation, and decreasing smooth muscle cell proliferation. The BVS also showed scavenging ability of reactive oxygen species and inhibition of toxic NO production, with suppressed inflammatory response and induced healthy blood vessel formation when implanted in mice. This offers a new tool for designing cardiovascular stents and various biological applications.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Biochemistry & Molecular Biology
Amir Asgari, Paul Jurasz
Summary: Megakaryocytes are important members of the hematopoietic system, responsible for regulating vascular homeostasis through platelets. The process of megakaryopoiesis generates mature megakaryocytes which release proplatelets into blood vessels. Nitric oxide (NO) plays a modulatory role in hematopoiesis and hemostasis. This review summarizes the effect of NO and its signaling on megakaryopoiesis and thrombopoiesis under physiological and pathophysiological conditions.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Medicinal
Estela M. G. Lourenco, Fernanda da Silva, Amarith R. das Neves, Iluska S. Bonfa, Alda Maria T. Ferreira, Adriana C. G. Menezes, Maria E. C. da Silva, Jessica T. dos Santos, Marco A. U. Martines, Renata T. Perdomo, Monica C. Toffoli-Kadri, Euzebio G. Barbosa, Sumbal Saba, Adilson Beatriz, Jamal Rafique, Carla C. P. de Arruda, Denis P. de Lima
Summary: Leishmaniases are neglected tropical diseases that have devastating health, social, and economic consequences. Current antileishmanial drugs are old, toxic, and unaffordable. A study synthesized 17 flavonoid derivatives and found that 11 of them showed high activity against the parasite and were safe for host cells.
ACS INFECTIOUS DISEASES
(2023)
Article
Chemistry, Multidisciplinary
Conrad A. P. Goodwin, Sierra R. Ciccone, Samuel Bekoe, Sourav Majumdar, Brian L. Scott, Joseph W. Ziller, Andrew J. Gaunt, Filipp Furche, William J. Evans
Summary: New coordination environments for Np(III) and Pu(III) are reported based on pilot studies, with U(III) also studied in the same context. Complexes obtained through reactions showed different electron configurations for U(III), Np(III), and Pu(III).
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Inorganic & Nuclear
Justin C. Wedal, Joseph W. Ziller, Filipp Furche, William J. Evans
Summary: Heteroleptic U(III) complexes supported by bis(cyclopentadienyl) frameworks were synthesized and evaluated as precursors to U(II) complexes. The complexes were compared with other related compounds, and their electrochemical behavior was studied, revealing redox couples for U(IV)/U(III) and U(III)/U(II) transitions. The targeted U(II) complexes were analyzed using density functional theory, showing a 5f(3)6d(1) electron configuration as the ground state in each case.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Krishnendu Kundu, Jessica R. K. White, Samuel A. Moehring, Jason M. Yu, Joseph W. Ziller, Filipp Furche, William J. Evans, Stephen Hill
Summary: By controlling the degree of s-orbital mixing in molecules, a large spin hyperfine interaction can be achieved, leading to a 9 GHz clock transition and increased phase memory time. These findings suggest new strategies for the development of molecular quantum technologies.
Article
Chemistry, Inorganic & Nuclear
Justin C. Wedal, Joseph W. Ziller, William J. Evans
Summary: This study found that 1,3,5-trimethyltriazacyclohexane readily adds to bismuth triiodide to form various coordination compounds with different structures and properties, depending on the stoichiometry, solvent, and crystallization conditions.
INORGANIC CHEMISTRY
(2022)
Article
Chemistry, Inorganic & Nuclear
Lauren M. Anderson-Sanchez, Jason M. Yu, Joseph W. Ziller, Filipp Furche, William J. Evans
Summary: The sterically bulky aryloxide ligand OAr* has been used to synthesize thermally stable Ln(II) complexes across the lanthanide series. Reduction of Ln(III) precursors Ln(OAr*)3 with potassium graphite and 2.2.2-cryptand yielded the Ln(II) complexes. The La and Ce complexes were challenging to isolate but could be obtained with the use of 18-crown-6 as a potassium chelator.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Justin C. Wedal, Jesse Murillo, Joseph W. Ziller, Brian L. Scott, Andrew J. Gaunt, William J. Evans
Summary: Me3tach readily complexes uranium triiodide to form (Me3tach)2UI3, which is soluble in THF and arenes and can serve as a source of UI3 to form organometallic U(III) complexes. When dissolved in pyridine, (Me3tach)2UI3 forms (Me3tach)UI3(py)2. A comparison was made with a related complex (Me3tacn)UI3(THF) using the larger ligand Me3tacn. Neptunium and plutonium complexes (Me3tach)2NpI3 and (Me3tach)2PuI3 were synthesized in a similar manner.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Amanda B. Chung, Cary R. Stennett, William N. G. Moore, Ming Fang, Joseph W. Ziller, William J. Evans
Summary: The reduction of tris(amide) complexes Ln(NR2)3 (R = SiMe3) with potassium graphite in the presence of various ethers demonstrates high reactivity, as shown by crystal structures of different C-O bond cleavage reactions. The study also highlights the diverse reaction pathways and difficulties in isolating Ln(II) complexes containing the [Ln(NR2)3]1- anion.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Cary R. Stennett, Joseph Q. Nguyen, Joseph W. Ziller, William J. Evans
Summary: The feasibility of using redox-active 2,2'-bipyridine as an electron carrier for lanthanide metallocenes was examined. The synthesis and characterization of Cp*2LnCl-(bipy) and Cp*2Ln(bipy) complexes were carried out. The complexes were then used to achieve two-electron reduction chemistry, including the reduction of azobenzene and the formation of lanthanide organometallic complexes with a (S5)2- ligand.
Article
Nanoscience & Nanotechnology
William N. G. Moore, Timothy J. McSorley, Alexandre Vincent, Joseph W. Ziller, Luis A. Jauregui, William J. Evans
Summary: The utility of molecular precursors for constructing van der Waals heterostructures was explored by studying the compound [(THF)Cs(mu- eta 5:eta 5-Cp ')3TmII]. Thin films were successfully exfoliated from single crystals and stacked under hexagonal boron nitride to create an air-stable van der Waals heterostructure.
ACS APPLIED NANO MATERIALS
(2023)
Editorial Material
Public, Environmental & Occupational Health
Amanda B. B. Chung, Cy H. Fujimoto, William J. Evans
Summary: We present a narrative of an incident in a chemistry laboratory involving the purification of benzene using a distillation apparatus. The incident resulted in an injury to a graduate student and a fire causing $3.5 million in damages. Unfortunately, due to the extent of the fire, the direct cause of the incident could not be determined. Lessons learned from this incident include conducting risk assessments, maintaining proper lab housekeeping, updating chemical inventory, monitoring long duration experiments, calling for backup, ensuring compliance with building codes, wearing personal protective equipment, and always calling 911 during emergencies.
ACS CHEMICAL HEALTH & SAFETY
(2023)
Article
Chemistry, Inorganic & Nuclear
Cory J. Windorff, Conrad A. P. Goodwin, Joseph M. Sperling, Thomas E. Albrecht-Schonzart, Zhuanling Bai, William J. Evans, Zachary K. Huffman, Renaud Jeannin, Brian N. Long, David P. Mills, Todd N. Poe, Joseph W. Ziller
Summary: This study aimed to find a trivalent plutonium halide phosphine oxide compound but accidentally isolated a tetravalent plutonium halide compound, which was characterized using various techniques. A putative plutonyl complex was also observed, and a series of similar compounds were synthesized for comparison.
INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Joseph Q. Nguyen, Lauren M. Anderson-Sanchez, William N. G. Moore, Joseph W. Ziller, Filipp Furche, William J. Evans
Summary: The importance of the specific trialkylsilyl substituent in the cyclopentadienyl chemistry of C5H4SiR3 ligands has been demonstrated by the synthesis of low oxidation-state thorium complexes. Crystalline tris(monosilyl-substituted cyclopentadienyl) Th(III) and Th(II) complexes can be isolated when the substituent is isopropyl.
Article
Chemistry, Inorganic & Nuclear
Justin C. Wedal, Joseph W. Ziller, William J. Evans
Summary: The reactions of 1,3,5-trimethyl-triazacyclohexane with rare-earth metal iodide, chloride, and triflate salts were investigated as alternative precursors for THF-free reactions. These reactions produced soluble (Me(3)tach)(2)LnI(3) and (Me(3)tach)(2)LnCl3 complexes with unique structures.
DALTON TRANSACTIONS
(2023)
Article
Chemistry, Inorganic & Nuclear
Justin C. Wedal, Joseph W. Ziller, William J. Evans
Summary: In this study, the U(v) imido complex 1 was observed for the first time by crystallography, providing new insights into the reaction mechanisms of U(III) compounds with azide reagents.
DALTON TRANSACTIONS
(2022)
Article
Chemistry, Multidisciplinary
Justin C. Wedal, Nathalia Cajiao, Michael L. Neidig, William J. Evans
Summary: A new synthesis of Th(ii) complexes has been discovered, which involves the addition of simple MX salts to Cp'' Th-3(III) in the presence of 18-crown-6 or 2.2.2-cryptand. This synthesis method is applicable to MX salts where M is Li, Na, K and X is H, Cl, Me, N-3.
CHEMICAL COMMUNICATIONS
(2022)
