General One-Pot Reductivegem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine
出版年份 2013 全文链接
标题
General One-Pot Reductivegem-Bis-Alkylation of Tertiary Lactams/Amides: Rapid Construction of 1-Azaspirocycles and Formal Total Synthesis of (±)-Cephalotaxine
作者
关键词
-
出版物
CHEMISTRY-A EUROPEAN JOURNAL
Volume 19, Issue 39, Pages 13075-13086
出版商
Wiley
发表日期
2013-08-16
DOI
10.1002/chem.201302096
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Direct Room-Temperature Lactonisation of Alcohols and Ethers onto Amides: An “Amide Strategy” for Synthesis
- (2013) Viviana Valerio et al. CHEMISTRY-A EUROPEAN JOURNAL
- General Direct Transformation of Secondary Amides to Ketones via Amide Activation
- (2012) Kaijiong Xiao et al. ACTA CHIMICA SINICA
- Direct Transformation of Secondary Amides into Secondary Amines: Triflic Anhydride Activated Reductive Alkylation
- (2012) Kai-Jiong Xiao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Beyond Directing Groups: Transition-Metal-Catalyzed CH Activation of Simple Arenes
- (2012) Nadine Kuhl et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- [RhIIICp*]-Catalyzed Dehydrogenative ArylAryl Bond Formation
- (2012) Joanna Wencel-Delord et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct Nucleophilic Addition toN-Alkoxyamides
- (2012) Yuta Yanagita et al. CHEMISTRY-A EUROPEAN JOURNAL
- Toward the Total Synthesis of Haliclonin A: Construction of a Tricyclic Substructure
- (2012) Shi-Peng Luo et al. CHEMISTRY-A EUROPEAN JOURNAL
- Formal Synthesis of (−)-Cephalotaxine Based on a Tandem Hydroamination/Semipinacol Rearrangement Reaction
- (2012) Qing-Wei Zhang et al. Chemistry-An Asian Journal
- Undirected Arene and Chelate-Assisted Olefin C-H Bond Activation: [RhIIICp*]-Catalyzed Dehydrogenative Alkene-Arene Coupling as a New Pathway for the Selective Synthesis of Highly SubstitutedZOlefins
- (2012) Joanna Wencel-Delord et al. Chemistry-An Asian Journal
- Copper-Catalyzed Oxidative Amidation of Aldehydes with Amine Salts: Synthesis of Primary, Secondary, and Tertiary Amides
- (2012) Subhash Chandra Ghosh et al. JOURNAL OF ORGANIC CHEMISTRY
- Chemoselective synthesis of ketones and ketimines by addition of organometallic reagents to secondary amides
- (2012) William S. Bechara et al. Nature Chemistry
- Efficient Synthesis of α-Tertiary α-Silylamines from Aryl Sulfonylimidates via One-Pot, Sequential C–Si/C–C Bond Formations
- (2012) Xiao-Jun Han et al. ORGANIC LETTERS
- A Formal Enantioselective Total Synthesis of FR901483
- (2012) Hao-Hua Huo et al. ORGANIC LETTERS
- Synthesis of tertiary carbinamines
- (2012) Muthoni G. Kamau et al. TETRAHEDRON
- Versatile and Direct Transformation of Secondary Amides into Ketones by Deaminative Alkylation with Organocerium Reagents
- (2012) Kai-Jiong Xiao et al. Asian Journal of Organic Chemistry
- Metathesis access to monocyclic iminocyclitol-based therapeutic agents
- (2011) Ileana Dragutan et al. Beilstein Journal of Organic Chemistry
- Quaternary centres bearing nitrogen (α-tertiary amines) as products of molecular rearrangements
- (2011) Jonathan Clayden et al. CHEMICAL COMMUNICATIONS
- Thioamides and Thioformamides for Sequential Reactions with Organolithium and Grignard Reagents
- (2011) Toshiaki Murai et al. CHEMISTRY LETTERS
- Progress in Metathesis Through Natural Product Synthesis
- (2011) Joëlle Prunet EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Synthesis of Novel Angular Spirocyclic Azetidines
- (2011) Carine Guérot et al. ORGANIC LETTERS
- Strategies and tactics in olefin metathesis
- (2011) Sambasivarao Kotha et al. TETRAHEDRON
- Tactics for the asymmetric preparation of 2-azabicyclo[3.1.0]hexane and 2-azabicyclo[4.1.0]heptane scaffolds
- (2011) Andrzej Wolan et al. TETRAHEDRON LETTERS
- A Direct Entry to Substituted N-Methoxyamines from N-Methoxyamides via N-Oxyiminium Ions
- (2010) Kenji Shirokane et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Direct, One-pot Sequential Reductive Alkylation of Lactams/Amides with Grignard and Organolithium Reagents through Lactam/Amide Activation
- (2010) Kai-Jiong Xiao et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Generation of Secondary, Tertiary, and Quaternary Centers by Geminal Disubstitution of Carbonyl Oxygens
- (2010) Dieter Seebach ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Stereodivergent Synthesis of Substituted N,O-Containing Bicyclic Compounds by Sequential Addition of Nucleophiles to N-Alkoxybicyclolactams
- (2010) Guillaume Vincent et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Efficient and chemoselective alkylation of amines/amino acids using alcohols as alkylating reagents under mild conditions
- (2010) Chu-Pei Xu et al. CHEMICAL COMMUNICATIONS
- Versatile One-Pot Reductive Alkylation of Lactams/Amides via Amide Activation: Application to the Concise Syntheses of Bioactive Alkaloids (±)-Bgugaine, (±)-Coniine, (+)-Preussin, and (−)-Cassine
- (2010) Kai-Jiong Xiao et al. CHEMISTRY-A EUROPEAN JOURNAL
- Strategies for Innovation in Multicomponent Reaction Design
- (2009) Bruce Ganem ACCOUNTS OF CHEMICAL RESEARCH
- Copper-Catalyzed Amine-Alkyne-Alkyne Addition Reaction: An Efficient Method For the Synthesis of γ,δ-Alkynyl-β-amino Acid Derivatives
- (2009) Lei Zhou et al. CHEMISTRY-A EUROPEAN JOURNAL
- Cephastigiamide A, and Antiplasmodial Activity of Cephalotaxus Alkaloids from Cephalotaxus harringtonia Forma Fastigiata
- (2009) Hiroshi Morita et al. HETEROCYCLES
- Sequential Addition Reactions of Two Molecules of Grignard Reagents to Thioformamides
- (2009) Toshiaki Murai et al. JOURNAL OF ORGANIC CHEMISTRY
- Highly Efficient Cu(I)-Catalyzed Synthesis ofN-Heterocycles through a Cyclization-Triggered Addition of Alkynes
- (2009) Junbin Han et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthetic transformations mediated by the combination of titanium(IV) alkoxides and grignard reagents: selectivity issues and recent applications. Part 1: reactions of carbonyl derivatives and nitriles
- (2009) Andrzej Wolan et al. TETRAHEDRON
- Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations
- (2008) Chao-Jun Li ACCOUNTS OF CHEMICAL RESEARCH
- Amide bond formation: beyond the myth of coupling reagents
- (2008) Eric Valeur et al. CHEMICAL SOCIETY REVIEWS
- Asymmetric Syntheses and Wnt Signal Inhibitory Activity of Melleumin A and Four Analogues of Melleumins A and B
- (2008) Jie-Min Luo et al. Chemistry-An Asian Journal
- Synthesis of Tertiarysec-Alkylamines by the Addition of Grignard Reagents toN,N-Dialkylformamides Mediated by Ti(OiPr)4and Me3SiCl
- (2008) Olesya Tomashenko et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- The Combination of Diallylboration and Ring-Closing Metathesis in the Synthesis of Spiro-β-Amino Alcohols and (±)-Cephalotaxine
- (2008) Nikolai Yu. Kuznetsov et al. EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
- Diastereoselective Synthesis ofN-Secondary Alkyl 2-Alkoxymethylpyrrolidines via Sequential Addition Reactions of Organolithium and -Magnesium Reagents toN-Thioformyl 2-Alkoxymethylpyrrolidines
- (2008) Toshiaki Murai et al. JOURNAL OF ORGANIC CHEMISTRY
- Synthesis of β-, γ-, and δ-Lactams via Pd(II)-Catalyzed C−H Activation Reactions
- (2008) Masayuki Wasa et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Cu(I)-Catalyzed C−H α-Amination of Esters. Direct Synthesis of Hydantoins
- (2008) Baoguo Zhao et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis of Indoles via Domino Reaction ofN-Aryl Amides and Ethyl Diazoacetate
- (2008) Sun-Liang Cui et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A Formal Synthesis of (-)-Cephalotaxine
- (2008) William R. Esmieu et al. ORGANIC LETTERS
- An Efficient Method To Convert Lactams and Amides into 2,2-Dialkylated Amines†
- (2008) Alessandro Agosti et al. ORGANIC LETTERS
- A Versatile Cascade of Intramolecular Vilsmeier−Haack and Azomethine Ylide 1,3-Dipolar Cycloaddition toward Tricyclic Cores of Alkaloids†
- (2008) François Lévesque et al. ORGANIC LETTERS
- Function-Oriented Synthesis, Step Economy, and Drug Design
- (2007) Paul A. Wender et al. ACCOUNTS OF CHEMICAL RESEARCH
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started