Review
Acoustics
Ingrid V. Machado, Jhonathan R. N. dos Santos, Marcelo A. P. Januario, Arlene G. Correa
Summary: By utilizing ultrasound-assisted multicomponent reactions under heterogeneous catalysis, it is possible to efficiently synthesize biologically active organic compounds with reduced costs and energy consumption.
ULTRASONICS SONOCHEMISTRY
(2021)
Review
Polymer Science
Guoqiang Liu, Ruihao Pan, Yen Wei, Lei Tao
Summary: The Hantzsch reaction is a powerful tool for synthesizing 1,4-dihydropyridine derivatives, and has recently been introduced into polymer chemistry for developing polymers with new functions. These polymers with 1,4-DHP structures have potential applications in various fields. The future development of the Hantzsch reaction is promising for exploring new functional polymers.
MACROMOLECULAR RAPID COMMUNICATIONS
(2021)
Review
Chemistry, Multidisciplinary
Marcelo O. Rodrigues, Marcos N. Eberlin, Brenno A. D. Neto
Summary: Elucidating multicomponent reactions (MCRs) mechanisms presents significant challenges and requires innovative approaches and unique techniques. Common methods are often inadequate for clarifying MCRs mechanisms, thus only a few clever methods are currently used to determine these mysterious mechanisms.
Review
Crystallography
Weiqing She, Zhenzhen Xu, Lianjie Zhai, Junlin Zhang, Jie Huang, Weiqiang Pang, Bozhou Wang
Summary: Due to the introduction of oxygen atoms, N-oxide energetic compounds possess unique advantages in terms of oxygen balance, detonation properties, and energy density, which have attracted extensive attention from researchers worldwide. This article provides a comprehensive review of the synthetic strategies for two categories of N-oxides, azine N-oxides and azole N-oxides, and discusses the reaction mechanisms of aromatic N-oxide frameworks and their applications in creating high-energy substances. Furthermore, the energetic properties of N-oxide energetic compounds are compared and summarized.
Article
Chemistry, Organic
Gabriela H. C. Oliveira, Luciana M. Ramos, Raissa K. C. de Paiva, Saulo T. A. Passos, Marina M. Simoes, Fabricio Machado, Jose R. Correa, Brenno A. D. Neto
Summary: This work utilized a synthetic enzyme as a catalyst for the multicomponent synthesis of isoxazol-5(4H)-one derivatives, investigating the reaction mechanism, determining the reaction pathway, and evaluating photophysical data. The kinetic model confirmed only one reaction pathway, and some progress was made in terms of antimicrobial abilities and imaging probes.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Wei Liu, Tianren Qin, Wansen Xie, Jinmiao Zhou, Zidan Ye, Xiaoyu Yang
Summary: We have developed an efficient modular asymmetric synthesis of azahelicenes from readily available polycyclic aromatic amines, aldehydes, and (di)enamides, employing a central-to-helical chirality conversion strategy. A series of aza[5]- and aza[4]helicenes bearing various substituents were easily obtained with good yields and high enantioselectivities. The diverse derivatizations and the preliminary application of the azahelicene derivative as a chiral organocatalyst demonstrated the potential of this method, and the photophysical and chiroptical properties of these azahelicenes were well studied, showing potential applications in novel organic optoelectronic materials.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Physical
Yong-Liang Su, Geng-Xin Liu, Luca De Angelis, Ru He, Ammar Al-Sayyed, Kirk S. Schanze, Wen-Hao Hu, Huang Qiu, Michael P. Doyle
Summary: This study demonstrates the efficient generation of functionalized derivatives through photocatalyzed multicomponent reactions using nitrogen aromatic heterocycles, alkenes, and diazo compounds. The reaction shows high functional group tolerance and exacting regioselectivities. Mechanistic studies, including photophysical measurements, provide insights into this radical cascade reaction.
Article
Thermodynamics
Sebastian Hesse, Laila Nazari, Gernot Friedrichs
Summary: The reaction behavior of the NCN radical in flames was studied and the rate constants of its important reactions were determined. The study found that the reaction between NCN and CH3 is highly significant, while the reaction between NCN and OH is relatively slow.
COMBUSTION AND FLAME
(2023)
Article
Polymer Science
Burcu Alkan, Ozgun Daglar, Serter Luleburgaz, Begum Gungor, Ufuk Saim Gunay, Gurkan Hizal, Umit Tunca, Hakan Durmaz
Summary: A novel one-pot cascade reaction was proposed for the synthesis and simultaneous modification of polyesters, utilizing the Passerini three-component reaction. The study emphasized the significance of temperature in achieving high molecular weight polymers and efficient reactions.
Article
Chemistry, Applied
Leon V. T. Bork, Paul Haase, Sascha Rohn, Clemens Kanzler
Summary: This study investigates the reaction between norfuraneol and different carbonyl compounds, as well as the underlying mechanisms. The results show that aldol reactions lead to the formation of carbohydrate-based oligomers, and redox reactions result in an increase in double bonds.
Review
Polymer Science
In-Hwan Lee, Ki-Taek Bang, Hee-Seong Yang, Tae-Lim Choi
Summary: Diversification of polymer structures is crucial for unique applications, and diversity-oriented polymerization (DOP) using multicomponent polymerization (MCP) has emerged as an efficient strategy. Cu-catalyzed MCP (Cu-MCP) has overcome previous challenges in MCP, paving the way for diverse and complex polymer structures. Future research will focus on the advancement and optimization of Cu-MCP for innovative polymer applications.
MACROMOLECULAR RAPID COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Alexandre Quelhas, Houda Gazzeh, Thierry Roisnel, Yann Trolez, Jean-Claude Guillemin
Summary: Kinetically unstable vinyl, allenyl and propargyl isocyanides react faster in Passerini and Ugi reactions than they decompose, leading to functionalized amides that can be further used in reactions involving unsaturated substituents.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Yasmin Wahby, Hamida Abdel-Hamid, Mohammed Salah Ayoup
Summary: Passerini three-component reactions based on isonitriles are impressive synthetic protocols that provide poly-functionalized compounds in a one-pot process. Recent advances in Passerini reactions have shown potential applications in the pharmaceutical field and the synthesis of various compounds over the past two decades.
NEW JOURNAL OF CHEMISTRY
(2022)
Article
Chemistry, Physical
Jianghao Zhou, Jing Guo, Alexander Moiseevich Mebel, Govinda Ghimire, Feng Liang, Shuai Chang, Jin He
Summary: Investigated the dehydration reaction of primary amides in visible-light driven self-assembled gold nanoparticle-aromatic primary amide-gold nanoelectrode junctions. Used time-resolved surface enhanced Raman spectroscopy (SERS) to study the reaction dynamics and intermediates, revealing the role of gold surface adatoms and picocavities in stabilizing and amplifying the intermediates.
Article
Chemistry, Physical
Atsumi Yoshiki, Yuta Sugino, Shogo Tendo, Rintaro Fukami, Hiroshi Kohguchi, Katsuyoshi Yamasaki
Summary: The rate coefficients for the reactions of CH with CHCl3 and CHBr3, as well as the correlation between the rate coefficients for the reactions of CH with CHnX4-n (X=F, Cl, and Br) and the heats of reactions for H-, Cl-, and Br- elimination, were investigated.
CHEMICAL PHYSICS LETTERS
(2022)