期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 17, 期 35, 页码 9738-9745出版社
WILEY-BLACKWELL
DOI: 10.1002/chem.201100383
关键词
ion mobility; molecular dynamics; mass spectrometry; polylactides; polymers
资金
- Wallonie Bruxelles International (WBI-FRS)
- Belgian Federal Science Policy Office [SSTC-PAI 6/27]
Ion mobility spectrometry coupled with mass spectrometry was used to experimentally determine the three-dimensional structure of multiply charged sodium cationized polylactides (PLA). In particular, the experiments were conducted to evaluate the influence of the charge state and the size on the gas-phase conformation of cationized PLA. The measured collision cross sections were then compared to calculated values obtained by computational chemistry methods. The most striking feature was the experimental and theoretical observation of a breaking point in the quasilinear relationship between the average collision cross sections and the number of monomer units for the triply charged cations. This breaking point was theoretically demonstrated, for the doubly and triply charged cations, to be associated with a significant folding of the polymer chains around the cationizing agents. The occurrence of such breaking points could be exploited to correlate the charge state of the most intense ion series observed upon electrospray ionization with the number-average molecular mass of a polymer.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据