Indole alkaloids from the marine bacterium Pantoea agglomerans

Five indole alkaloids and two phenylethylamine derivatives were isolated from the ethyl acetate extract of the fermentation broth of the marine bacterium Pantoea agglomerans P20-14. Their structures were identified as N-(4-hydroxyphenethyl)-2-(1H-indol-3-yl)acetamide (1), 3-(p-hydroxy)benzoyl indole (2), 1,2-di(1H-indol-3-yl)ethane (3), 1H-indole-3-carboxylic acid (4), 2-hydroxy-1-(1H-indol-3-y1)ethanone (5), N-acetyltyramine (6), and 2-(4-hydroxyphenethyl)-N-phenylacetamide (7). Compound 1 is a new indole alkaloid and compounds 2 and 3 are new natural products.The structures of the seven compounds were established on the basis of chemical and spectroscopic methods. The spectroscopic data of compound 2 is provided for the first time.