Article
Nanoscience & Nanotechnology
Clara Otero-Martinez, Nadesh Fiuza-Maneiro, Lakshminarayana Polavarapu
Summary: Metal halide perovskite nanocrystals have attracted attention in the research of colloidal semiconductor nanomaterials due to their properties and potential applications. However, their phase instability and chemical degradation hinder real-world applications. To address these issues, researchers have proposed strategies such as doping and encapsulation to enhance stability.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Shin Hum Cho, Ikhyun Kim
Summary: We report that doped metal oxide nanocrystal cubes show robustness in their infrared plasmonic absorption optical property under exposure to repeated hypersonic shockwaves. This study demonstrates the potential application of doped infrared plasmonic metal oxides in high-performance infrared optical filters and sensor devices in surface exposed hypersonic aerospace vehicles.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Tae Yeong Kim, Chaeheon Woo, Kyung Hwan Choi, Xue Dong, Jiho Jeon, Jungyoon Ahn, Xiaojie Zhang, Jinsu Kang, Hyung-Suk Oh, Hak Ki Yu, Jae-Young Choi
Summary: Low-dimensional Nb2Se9 nanocrystals were synthesized using a simple one-pot colloidal synthesis method with C18 organic solvents of varied terminal functional groups. Among them, ODE played a primary role, acting as both a solvent and a reducing and capping agent. Furthermore, the synergy between ODE and OLA was demonstrated to play an important role in morphology control.
Article
Chemistry, Physical
Philippe B. Green, Francisco Yarur Villanueva, Karl Z. Demmans, Christian J. Imperiale, Minhal Hasham, Ehsan Nikbin, Jane Y. Howe, Darcy C. Burns, Mark W. B. Wilson
Summary: The study identifies the native passivation of PbS-eCl NCs through 1D and 2D H-1 NMR, and reveals that the surface of these nanocrystals matches the behavior of lead halide perovskites. Through this insight, the study highlights the potential for manipulating PbS-eCl NCs in solution for wider use in optoelectronic devices.
CHEMISTRY OF MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Mouhong Lin, Jian Wang, Gyeong-Hwan Kim, Jianan Liu, Limin Pan, Yeonhee Lee, Jeong-Wook Oh, Yoonjae Jung, Sungjae Seo, Youngju Son, Jongwoo Lim, Jungwon Park, Taeghwan Hyeon, Jwa-Min Nam
Summary: This study developed a new one-pot heterointerfacial metamorphosis (1HIM) method that can form a variety of highly crystalline heterostructured nanoparticles at relatively low temperatures, including metal-semiconductor nanoframes. The technology offers a new paradigm for synthesizing heterostructures with unique or synergistic properties and functions.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Applied
Fan Xiang, Kexin Liu, Manman Zhao, Zhanxiong Li
Summary: This study demonstrates a simple and low-cost technique for directing modified cellulose nanocrystal self-assembly on the surface of cotton fabrics. The resulting coated fabric exhibits excellent antibacterial effect, water stability, mechanical stability, and chemical durability. It also possesses self-cleaning and oil-water separation properties. This coated fabric has the potential to revolutionize traditional textiles in stain protection, safety, and healthcare applications.
PROGRESS IN ORGANIC COATINGS
(2023)
Review
Chemistry, Multidisciplinary
Saona Seth, Chayanika Pathak
Summary: Energetic materials containing azoles are appealing due to their high nitrogen content and functional groups that can participate in non-covalent bonding interactions. The compound 4,4'-azobis(1,2,4-triazole) (ATRZ) has been used as a molecular precursor to derive tailor-made energetic materials with hydrogen-bond acceptor and metal coordination sites. This review discusses the development of energetic cocrystals, coordination polymers, and composites using ATRZ as a high-energy molecular scaffold.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Physical
Zhiqiang Cheng, Xiaoyou Niu, Shenlong Jiang, Qun Zhang
Summary: This study investigates the energy transfer process between excitons and plasmons in a hybrid WSe2/CuFeS2 system. The coupling strength between the excitonic WSe2 and the plasmonic CuFeS2 is found to modulate the efficiency of energy transfer, which takes place during the early decay of plasmons.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Chemistry, Multidisciplinary
Zeyuan Wei, Hengxu Li, Yujie Wang, Qiang Liu
Summary: The reactivity of metal-hydride complexes can be controlled by modifying ancillary ligands. In this study, a versatile and efficient NHC-based NNC-pincer Mn catalyst was designed to enhance the hydride-donor ability and reduce steric hindrance. The newly developed catalyst showed higher activity than the corresponding NNP-pincer Mn catalyst, enabling successful hydrogenation of a wide range of polar unsaturated compounds under mild conditions. This work presents a rare example of a general phosphine-free Mn-catalyzed hydrogenation system.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Olli E. E. Setala, Martin J. J. Prest, Konstantin D. D. Stefanov, Douglas Jordan, Matthew R. R. Soman, Ville Vahanissi, Hele Savin
Summary: By replacing traditional methods with surface nanoengineering, the performance of commercial backside illuminated CMOS image sensors can be significantly improved in terms of spectral range, photosensitivity, and dark current reduction.
Review
Chemistry, Physical
Qiang Yue, Bin Liu, Gang Liao, Bing-Feng Shi
Summary: Transition metal-catalyzed enantioselective C-H functionalization is a rapid method for obtaining chiral molecules. Chiral ligands based on the binaphthyl scaffold have played a significant role in asymmetric C-H functionalization.
Review
Chemistry, Physical
Qiang Yue, Bin Liu, Gang Liao, Bing-Feng Shi
Summary: Transition metal-catalyzed enantioselective C-H functionalization has become a powerful tool for accessing chiral molecules. Chiral ligands based on the binaphthyl scaffold have shown versatility in this field due to their unique stereochemical features and ease of fine-tuning steric and electronic properties.
Article
Chemistry, Multidisciplinary
Xingtai Chen, Tao Liu, Zhaoru Li, Xi-Tao Yin
Summary: Gas sensors, especially metal oxide semiconductors, have been widely used in various fields, and modification methods such as special structures, doping, and precious metal loading can improve their gas-sensitive performance. This review summarizes the progress in the modification of metal oxides, including their response, selectivity, and operating temperature, and focuses on the gas-sensitive mechanisms. The bottlenecks and future development prospects of current metal oxide semiconductor n-Butanol gas sensors are also discussed.
MATERIALS TODAY CHEMISTRY
(2023)
Article
Chemistry, Physical
Xiaohu Qian, Li Li, Yinan Wang, Zhaowen Tian, Haoyin Zhong, Wei Chen, Tao Chen, Jiajun Fu
Summary: By utilizing dynamic metal-ligand interactions to construct a metallo-supramolecular interphase crosslinked by Zn(II)-2,6-bis(1,2,3-triazol-4-yl)pyridines moieties, the stability issues caused by dendrite growth and water-induced parasitic reactions in aqueous zinc metal batteries can be effectively addressed. The designed metallo-supramolecular interphase with a dynamically crosslinked network shows enhanced mechanical resilience, selective transport of Zn2+ cations, and facilitation of the desolvation process. Additionally, this chemically inert and hydrophobic interphase can effectively reduce water-induced side reactions. As a result, stable Zn plating/stripping for 1200 hours at a high current density and capacity can be achieved, along with improved cycling stability in Zn//MnO2 full cells.
ENERGY STORAGE MATERIALS
(2023)
Article
Materials Science, Ceramics
Ze-Wei Huang, Kao-Shuo Chang
Summary: Spin-coating was used to fabricate amorphous high-entropy oxide films on Si substrates, showing promising performance with low leakage current density after forming gas annealing. The resulting stack exhibited distinct layers with a clearly defined interface between different materials and no substantial diffusion among them. Medium-entropy-oxide films and their MOS devices, fabricated for comparison, exhibited inferior performance.
CERAMICS INTERNATIONAL
(2021)
Article
Chemistry, Analytical
Zhicheng Jin, Narjes Dridi, Goutam Palui, Valle Palomo, Jesse V. Jokerst, Phillip E. Dawson, Qing-Xiang Amy Sang, Hedi Mattoussi
Summary: We describe the assembly and characterization of quantum dot (QD)-dye conjugates using a specifically designed peptide bridge to recognize and interact with a breast cancer biomarker. These conjugates serve as optically addressable probes, detecting the activity of the biomarker through Fo''rster resonance energy transfer. The conjugates demonstrate high sensitivity to enzymatic proteolysis and show potential for in vivo analysis.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Zhicheng Jin, Yi Li, Ke Li, Jiajing Zhou, Justin Yeung, Chuxuan Ling, Wonjun Yim, Tengyu He, Yong Cheng, Ming Xu, Matthew N. Creyer, Yu-Ci Chang, Pavla Fajtova, Maurice Retout, Baiyan Qi, Shuzhou Li, Anthony J. O'Donoghue, Jesse V. Jokerst
Summary: In this study, a colorimetric biosensor using plasmonic gold and surfactant-like peptides (SLPs) was developed, which exhibited a strong aggregation propensity of the FFPC tail without the polar DDD head. The SLPs had specificity towards the target protease M-pro, a biomarker for SARS-CoV-2. This simple and visual tool showed detection limits of 15.7, 20.8, and 26.1 nM for M-pro in phosphate buffer, exhaled breath condensate, and saliva, respectively, and may have potential in designing other protease testing methods.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Energy & Fuels
Binghan Jiang, Xue Liu, Fuling Wang, Jianwei Ren, Tianle Yang, Zhicheng Jin, Xiyou Li, Yanli Chen
Summary: In this study, a facile approach for the synthesis of Co-N-GA-1 catalyst for oxygen reduction reaction (ORR) was developed. Co-N-GA-1 demonstrated superior ORR performance with higher Co content and CoN content compared to Co-N-CB-1 and CoN-GA-2. Co-N-GA-1 also exhibited better performance than commercial Pt/C and most previously reported Co-based catalysts.
Article
Nanoscience & Nanotechnology
Zhicheng Jin, Justin Yeung, Jiajing Zhou, Maurice Retout, Wonjun Yim, Pavla Fajtova, Bryan Gosselin, Ivan Jabin, Gilles Bruylants, Hedi Mattoussi, Anthony J. O'Donoghue, Jesse V. Jokerst
Summary: Surface ligands play a critical role in controlling and defining the properties of colloidal nanocrystals. These aspects have been exploited to design nanoparticle aggregation-based colorimetric sensors. The researchers coated 13-nm gold nanoparticles (AuNPs) with different ligands and evaluated their aggregation propensity in the presence of three peptides. They found that specific ligands were suitable for electrostatic-based or dithiol-bridging aggregation, depending on the properties of the peptides. They also developed a modular peptide for colorimetric detection of the coronavirus main protease with high sensitivity.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Yong Cheng, Alex E. Clark, Wonjun Yim, Raina M. Borum, Yu-Ci Chang, Zhicheng Jin, Tengyu He, Aaron F. Carlin, Jesse V. Jokerst
Summary: TMPRSS2 is a protease that activates coronaviruses and promotes tumor progression. Inhibiting TMPRSS2 can reduce cancer invasion and prevent SARS-CoV-2 infection. Researchers have developed a responsive peptide-conjugated probe that can selectively image and screen TMPRSS2 inhibitors, which may have value in cancer detection, SARS-CoV-2 targeting, and protease inhibitor screening.
ANALYTICAL CHEMISTRY
(2023)
Review
Medical Laboratory Technology
Zhicheng Jin, Roger L. Bertholf, Xin Yi
Summary: Vitamin D has gained attention in recent years. Its bioactive form, 1,25(OH)(2)D, plays a critical role in regulating calcium and phosphorus levels and is involved in the immune system. However, measuring 1,25(OH)(2)D accurately is challenging due to its low concentration and lipophilicity.
CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Zhicheng Jin, Narjes Dridi, Goutam Palui, Valle Palomo, Jesse V. Jokerst, Philip E. Dawson, Qing-Xiang Amy Sang, Hedi Mattoussi
Summary: This study utilized stable PEGylated gold nanoparticles coupled with dye-labeled peptides as sensitive optically addressable sensors for determining the catalytic efficiency of MMP-14, a cancer biomarker. Real-time dye photoluminescence recovery triggered by MMP-14 hydrolysis was exploited to extract quantitative analysis of the proteolysis kinetics. Sub-nanomolar limit of detections for MMP-14 has been achieved using these hybrid bioconjugates. Theoretical considerations within a diffusion-collision framework were also used to describe the complexity and irregularity of enzymatic proteolysis.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Nanoscience & Nanotechnology
Wonjun Yim, Maurice Retout, Amanda A. Chen, Chuxuan Ling, Lubna Amer, Zhicheng Jin, Yu-Ci Chang, Saul Chavez, Karen Barrios, Benjamin Lam, Zhi Li, Jiajing Zhou, Lingyan Shi, Tod A. Pascal, Jesse V. Jokerst
Summary: Colorimetric biosensors based on gold nanoparticle aggregation face challenges such as matrix interference, poor specificity, and limited clinical sample utility. This study proposes a peptide-driven nanoscale disassembly approach, where electrostatically induced AuNP aggregates are dissociated in response to proteolytic cleavage. The dissociation peptides effectively disassemble plasmonic assemblies, including diverse matrices and other types of plasmonic nanoparticles like silver, providing a simple, matrix-insensitive, and versatile method for protease sensing.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Zhicheng Jin, Chuxuan Ling, Wonjun Yim, Yu-Ci Chang, Tengyu He, Ke Li, Jiajing Zhou, Yong Cheng, Yi Li, Justin Yeung, Ruijia Wang, Pavla Fajtova, Lubna Amer, Hedi Mattoussi, Anthony J. J. O'Donoghue, Jesse V. V. Jokerst
Summary: Investigations on the interactions between enzyme and coacervates showed that the condensed structure of coacervates can influence the interactions with embedded substrates. Oligopeptide-based coacervates containing a proteolytic cleavage site were designed and dissolved in the presence of the main protease implicated in the coronavirus lifecycle. Enzyme kinetics were modeled using Cy5.5-labeled peptides and it was found that the specificity constant of the coacervates was similar to that of the free substrate. Additionally, the type and quantity of dyes incorporated into the coacervates were found to affect enzyme kinetics.
Correction
Chemistry, Multidisciplinary
Wonjun Yim, Jiajing Zhou, Lekshmi Sasi, Jiayu Zhao, Justin Yeung, Yong Cheng, Zhicheng Jin, Wade Johnson, Ming Xu, Jorge Palma-Chavez, Lei Fu, Baiyan Qi, Maurice Retout, Nisarg J. Shah, Jinhye Bae, Jesse V. Jokerst
ADVANCED MATERIALS
(2023)
Article
Chemistry, Physical
Matthew N. Creyer, Maurice Retout, Zhicheng Jin, Wonjun Yim, Jesse V. Jokerst
Summary: This study optimizes the surface chemistry of gold nanoparticles (AuNPs), allowing stable conjugation with coiled-coil (CC) peptides while preserving the native polypeptide properties. By tuning the surface fraction of a neutral, mixed ligand layer, the degree of AuNP labeling with CCs can be controlled. The study demonstrates the dynamic surface properties of these CC-AuNPs and their utility as an energy-transfer-based caspase-3 sensor.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Qiantao Song, Yi Li, Zhicheng Jin, Hai Liu, Matthew N. Creyer, Wonjun Yim, Yanping Huang, Xiaobing Hu, Tengyu He, Yajuan Li, Shana O. Kelley, Lingyan Shi, Jiajing Zhou, Jesse V. Jokerst
Summary: This study reports the mild and unique formation of luminescent spherulites at room temperature using benzene-1,4-dithiol. These spherulites not only exhibit robust structure but also show broad clusterization-triggered emission. They also demonstrate biocompatibility and efficient cellular uptake, making them valuable as traceable drug carriers.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Analytical
Justin Yeung, Zhicheng Jin, Chuxuan Ling, Maurice Retout, Elany Barbosa da Silva, Manan Damani, Yu-Ci Chang, Wonjun Yim, Anthony J. O'Donoghue, Jesse V. Jokerst
Summary: Noroviruses are highly contagious and a leading cause of acute gastroenteritis worldwide. A new method using tunable peptide substrate and gold nanoparticles was proposed for colorimetric detection of the key protease in viral replication. This system is simple and accessible, making it an attractive tool for qualitative point-of-care diagnostics.
Article
Medical Laboratory Technology
Zhicheng Jin, Yongjun Liu, Min Cui
JOURNAL OF APPLIED LABORATORY MEDICINE
(2023)
Article
Chemistry, Multidisciplinary
Yu-Ci Chang, Zhicheng Jin, Ke Li, Jiajing Zhou, Wonjun Yim, Justin Yeung, Yong Cheng, Maurice Retout, Matthew N. Creyer, Pavla Fajtova, Tengyu He, Xi Chen, Anthony J. O'Donoghue, Jesse V. Jokerst
Summary: Electrostatic interactions play a crucial role in colloidal assembly. The Schulze-Hardy rule states that nanoparticles tend to coagulate more when exposed to counterions with higher charge valence. This study investigates how the Schulze-Hardy rule functions when using more complex charge carriers instead of simple electrolytes. The researchers designed cationic peptides with different valencies and found that their charge screening behaviors on anionic gold nanoparticles followed the six-power relationship in the Schulze-Hardy rule. This discovery also led to a simple and effective strategy for visually measuring SARS-CoV-2 main protease (M-pro). By understanding the fundamental disassembly of nanoparticles based on the Schulze-Hardy rule, this work offers potential in designing versatile substrates for colorimetric sensing of other proteases.