Article
Nanoscience & Nanotechnology
Liangliang Zhou, Bin Yu, Lilin Huang, Huiqun Cao, Danying Lin, Yingying Jing, Faiz Wali, Junle Qu
Summary: In this study, a nonblinking core-multishell InP/ZnSe/ZnS quantum dot was synthesized using a hydrofluoric acid etching passivation method. The nonblinking quantum dot exhibited high fluorescence efficiency, good photostability, and high targeting. These nonblinking quantum dots can be used for long-term super-resolution visualization of subcellular dynamics.
ACS APPLIED NANO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Yanping Wang, Yusen Yang, Dingke Zhang, Tong Zhang, Shiyi Xie, Yu Zhang, Yong-Biao Zhao, Xiaoyun Mi, Xiuling Liu
Summary: This study reports an exciton sensitizing approach to improve the performance of quantum-dot light-emitting diodes (QLEDs) by forming excitons on a phosphorescent-dye-doped layer and transferring their energies to adjacent quantum-dot layer. The fabricated red QLEDs using this method achieve record high efficiency and good stability.
ADVANCED MATERIALS
(2023)
Article
Nanoscience & Nanotechnology
Chien-Yu Chen, Chia-Chun Ni, Ruei-Nan Wu, Sheng-Yang Kuo, Chia-Hao Li, Yean-Woei Kiang, C. C. Yang
Summary: The study reveals that surface plasmon coupling reduces FRET efficiency and creates competition. While R6G emission efficiency can be enhanced through SP coupling, the enhancement decreases when R6G is linked onto QD and then self-assembled onto Ag NP, especially when the number of R6G molecules is high.
Article
Nanoscience & Nanotechnology
Megan K. Dunlap, Duncan P. Ryan, Peter M. Goodwin, Chris J. Sheehan, James H. Werner, Somak Majumder, Jennifer A. Hollingsworth, Martin P. Gelfand, Alan Van Orden
Summary: Time-resolved super-resolution microscopy and scanning electron microscopy were combined to image individual CdSe/CdS quantum dots and quantum dot dimers. Nanometer scale spatial resolution and sub-nanosecond time resolution were used to acquire photoluminescence lifetimes, intensities, and structural parameters. The combination of these techniques allowed for the resolution of photoluminescence properties of individual quantum dots within dimers, measurement of interparticle distances, and identification of quantum dots involved in energy transfer.
Article
Biophysics
Ganapathi Bharathi, Fangrui Lin, Liwei Liu, Tymish Y. Ohulchanskyy, Rui Hu, Junle Qu
Summary: Ovarian cancer is a deadly disease threatening women's health, and late diagnosis is a major reason for related deaths. Using HE4 as a biomarker can improve the accuracy of ovarian cancer diagnosis. Developing an all-graphene quantum dot FRET probe allows for ratiometric detection of the HE4 ovarian cancer biomarker.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2021)
Article
Physics, Multidisciplinary
Jonas Meinel, Minsik Kwon, Rouven Maier, Durga Dasari, Hitoshi Sumiya, Shinobu Onoda, Junichi Isoya, Vadim Vorobyov, Joerg Wrachtrup
Summary: In this study, a new method for detecting nuclear magnetic resonance (NMR) signals at high magnetic fields using heterodyne detection is introduced. By utilizing a series of phase coherent electron nuclear double resonance sensing blocks, the limitations of heterodyne detection at high magnetic fields are overcome, allowing for chemical shift resolution in NMR experiments.
COMMUNICATIONS PHYSICS
(2023)
Article
Multidisciplinary Sciences
Katherine A. Cochrane, Jun-Ho Lee, Christoph Kastl, Jonah B. Haber, Tianyi Zhang, Azimkhan Kozhakhmetov, Joshua A. Robinson, Mauricio Terrones, Jascha Repp, Jeffrey B. Neaton, Alexander Weber-Bargioni, Bruno Schuler
Summary: The authors demonstrate the creation and characterization of effective spin 1/2 defects in 2D WS2 by atomically controlling the generation of magnetic carbon radical ions. These defects are anticipated building blocks for quantum technologies and exhibit well-understood vibronic spectra, with coupling strength varying based on the spin state and material thickness.
NATURE COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Vincent Notot, Willem Walravens, Maxime Berthe, Nemanja Peric, Ahmed Addad, Xavier Wallart, Christophe Delerue, Zeger Hens, Bruno Grandidier, Louis Biadala
Summary: The doping in square and epitaxially fused PbSe quantum dot superlattices was explored using low-temperature scanning tunneling microscopy and spectroscopy. The study found that the electronic coupling between quantum dots leads to the release and capture of free holes.
Article
Physics, Multidisciplinary
Shuai Liu, Jun-Hui Shen, Ri-Hua Zheng, Yi-Hao Kang, Zhi-Cheng Shi, Jie Song, Yan Xia
Summary: This paper proposes a scheme for implementing nonadiabatic holonomic quantum computation of two Rydberg atoms using invariant-based reverse engineering. The scheme utilizes Forster resonance induced by dipole-dipole interaction and introduces optimal control methods to improve the fidelity of the scheme.
FRONTIERS OF PHYSICS
(2022)
Article
Optics
A. Tsukanov, I. Yu Kateev
Summary: A spectroscopic method is proposed to determine the number of electrons in a quantum dot (QD) located inside a microdisk resonator. A transducer composed of single-electron QDs in the form of a ring structure is used as an auxiliary element to enhance the interaction between laser photons and the QD and microdisk. The calculation of microdisk parameters ensures efficient energy exchange between the disk modes and the transducer QDs. The influence of the Stark and Forster effects on measurement accuracy is studied and it is shown that the optimal measurement regime can be achieved when both effects are compensated.
LASER PHYSICS LETTERS
(2022)
Article
Nanoscience & Nanotechnology
Miho Takada, Kosuke Inoue, Hiroshi Sugimoto, Minoru Fujii
Summary: The photoelectrochemical response of a photocathode made from colloidal solution of boron and phosphorus codoped silicon quantum dots was studied. Codoping increased oxidation resistance of the Si QDs and enabled the electrode to operate as a photocathode. The size of the QDs strongly influenced the photocurrent, transitioning from anodic to cathodic at around 4 nm in diameter.
Article
Chemistry, Analytical
Marketa Prochazkova, Eliska Kuchovska, Michael Killinger, Karel Kleparnik
Summary: In this study, a molecular probe based on Fo center dot rster resonance energy transfer (FRET) was designed and synthesized for investigating biological phenomena at a single-cell level. The probe utilizes a highly luminescent quantum dot (QD) as a donor and a specific peptide as a linker to a fluorophore or fluorescence quencher as an acceptor. The synthesized probe showed high reaction yield and specificity, and provided longer imaging times of caspases compared to commercial products.
ANALYTICA CHIMICA ACTA
(2023)
Article
Nanoscience & Nanotechnology
Mohsen Azadinia, Tyler Davidson-Hall, Dong Seob Chung, Atefeh Ghorbani, Fatemeh Samaeifar, Junfei Chen, Peter Chun, Quan Lyu, Giovanni Cotella, Hany Aziz
Summary: Using a wider band gap quantum dot layer as an interlayer can improve the performance of inverted quantum dot light-emitting devices with a polymeric hole transport layer, resulting in higher efficiency and longer lifetime.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Chengzhao Luo, Zhishuai Zheng, Yanhui Ding, Zhenwei Ren, Hengfei Shi, Huifeng Ji, Xin Zhou, Yu Chen
Summary: In this study, a strategy of electrostatic force-induced deposition (EF-ID) is proposed to improve the pixel accuracy and transmittance of quantum dot light-emitting diodes (QLEDs). By introducing alternating polyethyleneimine (PEI) and fluorosilane patterns, the resolution and transparency of QD patterns are synergistically improved. High-performance QLEDs with high resolution and efficiency, as well as transparent QLEDs with the highest transmittance, are achieved.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xiaotong Fan, Shuli Wang, Xiao Yang, Chenming Zhong, Guolong Chen, Changzhi Yu, Yihang Chen, Tingzhu Wu, Hao-Chung Kuo, Yue Lin, Zhong Chen
Summary: This study proposes a bicomponent perovskite nanocomposite (BPNC) for color conversion layers in micro-light-emitting-diode (micro-LED) arrays, which significantly enhances the photoluminescence intensity through the built-in Forster resonance energy transfer (FRET) from the core CsPbBr3 to the shell gamma-CsPbI3. The FRET is conducted through a pair of combined quasi-degenerate energy levels in the blue spectra region, resulting in high excitation wavelength selectivity. The BPNC exhibits the brightest single-peak red photoluminescence with near 100% quantum yield and is adaptable to a wide range of emission wavelengths when used as color downconversion layers in a blue micro-LED array.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Physical
Shiori Yamazaki, Eunkeu Oh, Kimihiro Susumu, Igor L. Medintz, Amy M. Scott
Summary: Gold nanoclusters (AuNCs) are a new class of photoluminescent nanomaterials with potential applications in chemistry and biology. Functionalized AuNCs can act as energy-transfer acceptors with long-lived lifetimes, and their interaction with semiconductor quantum dots (QDs) has been studied using femtosecond and nanosecond spectroscopy techniques. The results show complex energy transfer processes and coherent vibrations in aqueous AuNC solutions.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Physical
Okhil K. Nag, Megan E. Muroski, Lauren D. Field, Michael H. Stewart, Eunkeu Oh, Kimihiro Susumu, Joseph R. Spangler, Scott A. Walper, James B. Delehanty
Summary: The study introduces a novel approach utilizing nanoparticle bioconjugates to activate channelrhodopsin C1V1 (ChR-C1V1) in HEK 293T/17 cell membranes. It demonstrates the specific activation of ChR-C1V1 channels through laser-induced opening with photoexcited quantum dots as an energy donor. This work represents a new hybrid system for controlling ion channel activity by interfacing quantum dots with living cells.
PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION
(2021)
Article
Nanoscience & Nanotechnology
David A. Hastman, Parth Chaturvedi, Eunkeu Oh, Joseph S. Melinger, Igor L. Medintz, Lela Vukovic, Sebastian A. Diaz
Summary: This study investigates the impact of local temperature changes on the dehybridization of double-stranded DNA. By varying the distance between DNA and nanoparticles as well as the energy fluence of laser pulses, the researchers achieve control over the dehybridization rate and release of DNA.
ACS APPLIED MATERIALS & INTERFACES
(2022)
Article
Nanoscience & Nanotechnology
Shelby Hooe, Joyce Breger, Scott Dean, Kimihiro Susumu, Eunkeu Oh, Scott Walper, Gregory A. Ellis, Igor L. Medintz
Summary: Cell-free enzymatic cascades are efficient, selective, and environmentally sustainable strategies for synthesizing complex organic molecules. Immobilizing enzymes onto nanoparticle surfaces can enhance catalytic rate and enzymatic efficiency, and enable substrate channeling in coupled activity.
ACS APPLIED NANO MATERIALS
(2022)
Article
Biochemical Research Methods
Katherine E. Rogers, Okhil K. Nag, Kimihiro Susumu, Eunkeu Oh, James B. Delehanty
Summary: In mammalian cells, the plasma membrane potential is controlled by a network of membrane-resident ion channels. Previous work has utilized spherical gold nanoparticles (AuNS) to induce membrane depolarization. In this study, new anisotropic-shaped gold nanoflowers (AuNFs) with absorption in the near-infrared range were used to effectively depolarize cells.
BIOCONJUGATE CHEMISTRY
(2023)
Article
Chemistry, Physical
Ajmeeta Sangtani, Kwahun Lee, Okhil K. Nag, Kimihiro Susumu, R. Joseph Weiblen, Mijin Kim, Igor Vurgaftman, Sz-Chian Liou, James B. Delehanty, Eunkeu Oh
Summary: Thiol-based ligands are commonly used for surface modification of metal nanoparticles, but the direct synthesis of non-spherical gold nanoparticles has been limited. In this study, we developed a one-step method to synthesize multipod-shaped gold nanoparticles by controlling the reducing power, acidity, and reagent stoichiometry. The physicochemical properties of these gold nanoparticles can be modulated by modifying the terminal groups and length of the ligands.
CHEMISTRY OF MATERIALS
(2022)
Article
Biochemical Research Methods
Divita Mathur, Meghna Thakur, Sebastian A. Diaz, Kimihiro Susumu, Michael H. Stewart, Eunkeu Oh, Scott A. Walper, Igor L. Medintz
Summary: Cell-free synthetic biology is a valuable tool for developing portable biosensors. By using a modular quantum dot-based reporter platform, it is possible to detect multiple analytes simultaneously.
ACS SYNTHETIC BIOLOGY
(2022)
Article
Multidisciplinary Sciences
Joyce C. C. Breger, James N. N. Vranish, Eunkeu Oh, Michael H. H. Stewart, Kimihiro Susumu, Guillermo Lasarte-Aragone's, Gregory A. A. Ellis, Scott A. A. Walper, Sebastian A. Diaz, Shelby L. L. Hooe, William P. P. Klein, Meghna Thakur, Mario G. G. Ancona, Igor L. L. Medintz
Summary: Enzymes in multistep cascades can self-assemble with nanoparticles into nanoclusters, allowing for directed substrate transport and significant improvement in catalytic flux. Efficiency of the channeling can be enhanced by optimizing enzymatic stoichiometry, using two-dimensional nanoplatelets, and ordering the enzyme assembly. Detailed analyses confirm the formation of the assembly and clarify the structure-function properties, verifying the generalized applicability of these self-assembled biocatalytic nanoclusters.
NATURE COMMUNICATIONS
(2023)
Article
Chemistry, Multidisciplinary
David A. Hastman, Eunkeu Oh, Joseph S. Melinger, Christopher M. Green, Aaron J. P. Thielemann, Igor L. Medintz, Sebastian A. Diaz
Summary: This study investigates the effect of plasmonic gold nanoparticle (AuNP) size on the rate of thermal release of single-stranded oligonucleotides under femtosecond (fs)-pulsed laser irradiation. Contrary to theoretical predictions, smaller AuNP diameters lead to faster DNA denaturation rates. Controlling for other factors yields the same result, suggesting that direct energy transfer may play a significant role as AuNPs decrease in size.
Article
Chemistry, Multidisciplinary
Joyce C. Breger, Ellen R. Goldman, Kimihiro Susumu, Eunkeu Oh, Christopher M. Green, Shelby L. Hooe, Meghna Thakur, Igor L. Medintz, Gregory A. Ellis
Summary: Enzyme activity can be greatly enhanced when displayed on nanoparticles, and this phenomenon can also improve the efficiency of coupled enzymatic processes. In this study, glucose dehydrogenase (GDH) displayed on nanocrystalline semiconductor quantum dots (QDs) showed a 5-fold increase in the reduction of nicotinamide adenine dinucleotide (NAD(+) -> NADH). By coupling GDH with lactate dehydrogenase (LDH) on QD-based nanoclusters, the rate of lactate to pyruvate conversion was also increased by a similar amount.
Article
Biochemical Research Methods
Katherine E. Rogers, Okhil K. Nag, Michael H. Stewart, Kimihiro Susumu, Eunkeu Oh, James B. Delehanty
Summary: In mammalian cells, growth factor-induced intracellular signaling and protein synthesis are crucial for cellular physiology and homeostasis. Researchers have developed a method using semiconductor quantum dots to enhance the expression of AQPN-4 in human astrocytes, resulting in improved water transport and increased signaling activity. This study demonstrates the potential of nanoparticle bioconjugates for modulating cellular signaling and understanding glymphatic system function.
BIOCONJUGATE CHEMISTRY
(2023)
Review
Pharmacology & Pharmacy
Okhil K. Nag, Kwahun Lee, Michael H. Stewart, Eunkeu Oh, James B. Delehanty
Summary: This review summarizes the progress made over the past 5 years in the use of various nanoparticle bioconjugates for the therapeutic delivery of nitric oxide. The advantages and challenges of using these materials for controlled nitric oxide delivery are discussed. Nitric oxide plays critical roles in cellular health and disease, but its physicochemical properties present challenges for specific and efficient delivery. Recent research has focused on utilizing nanoparticle carriers to enhance nitric oxide delivery.
THERAPEUTIC DELIVERY
(2022)