Article
Chemistry, Multidisciplinary
Xinlei Yao, Maxime Vonesch, Maiwenn Combes, Jean Weiss, Xiaonan Sun, Jean-Christophe Lacroix
Summary: This study demonstrates the preparation of highly stable single-molecule junctions using diazonium grafting approach. The conductance of porphyrin oligomers is relatively efficient and influenced by the presence of cobalt center, showing a long stability around 10 seconds. Random telegraph signals easily record on/off states of SMJs, indicating the potential applications of this approach in constructing stable molecular junctions.
Article
Chemistry, Multidisciplinary
Woojung Lee, Shayan Louie, Austin M. Evans, Nicholas M. Orchanian, Ilana B. Stone, Boyuan Zhang, Yujing Wei, Xavier Roy, Colin Nuckolls, Latha Venkataraman
Summary: This study demonstrates that dynamic molecular structures lead to temperature-dependent conductance in molecular wires. Thermally activated dihedral rotations increase the probability of molecular wires being in a planar conformation, enhancing tunneling probability. Longer molecular wires with more rotational pivot points exhibit larger temperature dependence on conductance.
Article
Chemistry, Multidisciplinary
Stepanka Novakova Lachmanova, Viliam Kolivoska, Jakub Sebera, Jindrich Gasior, Gabor Meszaros, Gregory Dupeyre, Philippe P. Laine, Magdalena Hromadova
Summary: This study demonstrates environmental control over the formation and conductance of expanded pyridinium molecules in single-molecule junctions, with more stable and conductive structures formed in a water environment compared to non-solvating conditions. Theoretical calculations accurately model single-molecule conductance values, taking into account the experimental junction length. The concept of tuning conductance through molecule-electrode interactions in solvent-driven junctions can potentially be applied in the development of new molecular electronic devices.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Kai Qu, Ping Duan, Jin-Yun Wang, Bochao Zhang, Qian-Chong Zhang, Wenjing Hong, Zhong-Ning Chen
Summary: This study successfully identified the internal rotation of three crank-shaped molecules using scanning tunneling microscope break junction technique and theoretical simulation. Theoretical computational study demonstrated that the orbital energy changes with the conformational flipping, affecting the single-molecule conductance.
Article
Chemistry, Multidisciplinary
Haipeng B. Li, Yan-Feng Xi, Ze-Wen Hong, Jingxian Yu, Xiao-Xia Li, Wen-Xia Liu, Lucas Domulevicz, Shan Jin, Xiao-Shun Zhou, Joshua Hihath
Summary: By studying a series of rigid, planar furan oligomers, we found that tunneling transport can change with temperature. Analyzing the correlation between molecular orbital energy offset and the Fermi level, we conclude that thermally assisted tunneling is the main cause for the temperature-dependent conductance in these systems.
Article
Materials Science, Multidisciplinary
Huanyan Fu, Cong Zhao, Jie Cheng, Shuyao Zhou, Peizhen Peng, Jie Hao, Zhirong Liu, Xike Gao, Chuancheng Jia, Xuefeng Guo
Summary: This study designs an azulene-based single-molecule FET with ambipolar characteristics and improved gate controllability using ionic liquid gating. Experimental and theoretical research show that the inherent dipole moment of azulene is crucial for achieving high-efficiency gate control.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)
Article
Chemistry, Multidisciplinary
Ryuto Yasui, Daiki Shimizu, Kenji Matsuda
Summary: The single-molecular conductance between two pi-conjugated wires with and without a radical substituent has been compared. The study found that the radical-substituted wire has significantly higher conductance than the methyl-substituted reference, despite the fact that only a small portion of the radical is distributed on the wire. This study demonstrates the potential of radical substituents in achieving high conductivity in molecular wires.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Editorial Material
Chemistry, Multidisciplinary
Ryuto Yasui, Daiki Shimizu, Kenji Matsuda
Summary: This study compares the single-molecular conductance between pi-conjugated wires with and without a radical substituent. The results show that the radical-substituted wire has 3.2 times higher conductance than the methyl-substituted reference. This study demonstrates the potential of radical substituents to achieve high conductivity in molecular wires.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Ana M. Ortuno, Pablo Reine, Luis alvarez de Cienfuegos, Irene R. Marquez, Wynand Dednam, Enrico B. Lombardi, Juan J. Palacios, Edmund Leary, Giovanna Longhi, Vladimiro Mujica, Alba Millan, M. Teresa Gonzalez, Linda A. Zotti, Delia Miguel, Juan M. Cuerva
Summary: We report on the chemical design of chiral molecular junctions with stress-dependent conductance, whose helicity is maintained during the stretching of a single molecule junction due to the stapling of both ends of the inner helix. The conductance values and plateau-length distributions of the reported compounds show different pathways and conformations of the helical structures. Density Functional Theory calculations demonstrate the large chiro-optical responses and potential use of these molecules as unimolecular spin filters with ab-initio estimation of CISS-originating spin polarization for a realistic molecular system.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Chemistry, Multidisciplinary
Yuxin Yang, Tao Jiang, Ye Tian, Biaofeng Zeng, Longhua Tang
Summary: Electrical tunneling sensors have great potential in single-molecule measurement and sequencing technologies due to their high sensitivity and spatial resolution. However, correlating signal transformations with molecular processes remains challenging. By combining intelligent machine learning with tunneling electrical signals and using clustering methods and customized statistical algorithms, meaningful information can be extracted from the data for more effective analysis.
CHINESE JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Bintian Zhang, Eathen Ryan, Xu Wang, Weisi Song, Stuart Lindsay
Summary: DNA molecular wires have been extensively studied, while the same is not true for proteins. In this study, a series of consensus tetratricopeptide repeat (CTPR) proteins were synthesized and studied, and it was found that their conductance exceeded that of the canonical molecular wire oligo(phenylene-ethylenene). The decay of conductance with length in the protein followed an exponential pattern, characteristic of quantum tunneling, and a square-law dependence on length, characteristic of weakly driven hopping. Measurements of the energy dependence of the decay length ruled out the quantum tunneling case, and a resonance in the carrier injection energy showed alignment with the Fermi energy of the electrodes.
Article
Chemistry, Multidisciplinary
Shaoqing Du, Yoshifumi Hashikawa, Haruka Ito, Katsushi Hashimoto, Yasujiro Murata, Yoshiro Hirayama, Kazuhiko Hirakawa
Summary: In this study, electron transport through H2O@C-60 single molecule transistors (SMTs) was investigated, revealing the presence of multiple tunneling-induced excited states below 30 meV. Terahertz (THz) photocurrent spectroscopy on H2O@C-60 SMTs confirmed the same excitations, with quantum rotational excitations of the water molecule observed below 10 meV. The simultaneous observation of quantum rotational excitations of both para- and ortho-water molecule for a single water molecule suggests a rapid fluctuation between the two states due to interaction with conducting electrons.
Review
Chemistry, Physical
Zixiao Wang, Bo Jiang, Hui Wang, Wei Wang
Summary: The relationship between electrochemical electron transfer and charge transport processes in chemical and biological molecule junctions is investigated by analyzing the switching events of electrical current from single molecule bridge tuning by electrochemical gating.
CURRENT OPINION IN ELECTROCHEMISTRY
(2022)
Review
Biochemistry & Molecular Biology
Mong-Wen Gu, Chun-hsien Chen
Summary: The contact between molecules and electrodes is crucial for electron transport in molecule-based devices. The electrode-molecule-electrode configuration is used as a testbed to quantitatively study the underlying physical chemistry. This review focuses on examples of electrode materials and introduces basic concepts and experimental techniques.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Physical
Abdalghani Daaoub, Luca Ornago, David Vogel, Pablo Bastante, Sara Sangtarash, Matteo Parmeggiani, Jerry Kamer, Hatef Sadeghi, Herre van der Zant, Marcel Mayor, Nicolas Agrait
Summary: This study investigates the influence of side groups on charge transport through single molecules and demonstrates the ability of side groups to modulate the energy levels of transport orbitals. A novel statistical method to predict the electrical conductance of molecular junctions is also proposed.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2022)
Review
Chemistry, Physical
Shiqiang Zhao, Hang Chen, Qiaozan Qian, Hewei Zhang, Yang Yang, Wenjing Hong
Summary: This review discusses the fabrication methods and construction routes of non-covalent interaction-based molecular electronic devices with graphene electrodes, as well as the recent progress in designing new-type molecular devices based on graphene and graphene-like 2D materials. The review also provides a prospect on the challenges and opportunities of non-covalent interaction-based molecular electronics.
Article
Chemistry, Multidisciplinary
Caiyun Wei, Jingyao Ye, Yuming Su, Jueting Zheng, Siqiang Xiao, Jiawei Chen, Saisai Yuan, Chengyang Zhang, Jie Bai, Han Xu, Jia Shi, Jiale Huang, Wenjing Hong
Summary: Due to the coverage of bulky ligands, coupling between electrode and noble metal clusters has been challenging. Using scanning tunneling microscopy break junction technique, we developed a direct contact method for fabrication and investigation of charge transport through single-cluster junctions of AgCu bimetallic metal clusters with different halide anchors. Experiments and calculations show that halide anchors provide efficient coupling between the cluster and the electrode, resulting in enhanced electron transport and improved transmission probability.
Article
Engineering, Aerospace
Jiahao Xing, Lichen Su, Wenjing Hong, Lu Tong, Renli Lyu, Wenbo Du
Summary: The collaborative routing of drones and trucks is important for flexible logistics services, especially when considering time constraints. This study proposes a Vehicle Routing Problem with Drones under Time constraints (VRPD-T) and develops a mixed-integer linear programming model and a hybrid heuristic-based algorithm to effectively solve large-scale complex problems. The numerical results validate the effectiveness of the proposed algorithm.
CHINESE JOURNAL OF AERONAUTICS
(2023)
Article
Chemistry, Analytical
Xuejun Dong, Ziyun Tang, Hua Zhang, Yong Hu, Zhiyi Yao, Ruiyun Huang, Jie Bai, Yang Yang, Wenjing Hong
Summary: In this study, a highly sensitive acetylcholinesterase sensor based on 3,3',5,5'-tetramethylbenzidine(TMB) and scanning tunneling microscopy break junction (STM-BJ) was developed for the detection of organophosphorus pesticides (OPs) in environmental samples. By utilizing the enzyme inhibition kinetics of OPs and a customized spectral clustering analysis method, the sensor achieved the detection of methamidophos (MTMP) with a limit of 10 aM (10(-17) mol/L) and improved selectivity for mixed OPs. The sensor also demonstrated high reproducibility, stability, and recovery when applied to natural lake waters. This work opens up a new avenue for the application of single-molecule conductance characterizations in biochemical analysis and environmental monitoring.
ANALYTICAL CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Iain A. A. Wright, Marc K. K. Etherington, Andrei S. S. Batsanov, Andrew P. P. Monkman, Martin R. R. Bryce
Summary: Heterocyclic dimers composed of butterfly-shaped phenothiazine and its oxidized form have been synthesized and studied. The presence of certain substituents induces a twist in the dimers. Various analytical techniques, including X-ray crystallography and optical spectroscopy, have been used to understand the relationship between oxidation state, conformational restriction, and emission mechanisms. The mixed dimer exhibits both thermally activated delayed fluorescence and room temperature phosphorescence.
CHEMISTRY-A EUROPEAN JOURNAL
(2023)
Article
Multidisciplinary Sciences
Jinxin Wang, Yongjie Zhao, Shumu Li, Lingyun Shen, Hao Zhang, Caijun Ding, Chang Wei, Yanfang Wang, Yongfang Li, Wenjing Hong, Mao Li
Summary: Understanding the charge transport in sequence-controlled molecules has been a challenge due to the need for controlled synthesis and orientation. We demonstrate a general strategy of electrically driven simultaneous synthesis and crystallization to study the conductance of composition and sequence-controlled monolayers. By synthesizing monolayers uniformly between electrodes, structural disorder and conductance variations are minimized, enabling reproducible measurements on the micrometer scale. These monolayers exhibit tunable current density, on/off ratios, multistate behavior, and negative differential resistance effects.
Article
Multidisciplinary Sciences
Yu-Ling Zou, Qing-Man Liang, Taige Lu, Yao-Guang Li, Shiqiang Zhao, Jian Gao, Zi-Xian Yang, Anni Feng, Jia Shi, Wenjing Hong, Zhong-Qun Tian, Yang Yang
Summary: Single-molecule electronics enable miniaturization of electronic devices, but current experiments are limited to traditional molecular structures. We developed layer-by-layer single-molecule heterojunctions using single-layer graphene electrodes, called single-molecule two-dimensional van der Waals heterojunctions (M-2D-vdWHs), which can be defined by the thickness of the molecule. By controlling the electric field, we demonstrated reversible switching behavior of the M-2D-vdWHs. These results show that stacked M-2D-vdWHs, composed of single-layer 2D materials and a single molecule, can respond to electric field stimulus, offering potential for unprecedentedly small single-molecule devices.
Article
Chemistry, Physical
Aihui Zhang, Xiaoyan Zhuang, Jia Liu, Jiacheng Huang, Luchun Lin, Yongxiang Tang, Shiqiang Zhao, Ruihao Li, Binju Wang, Baishan Fang, Wenjing Hong
Summary: Using the scanning tunnelling microscope break-junction technique, different reaction states in the catalytic cycle of formate dehydrogenase were identified and conductance was used as a marker to monitor the catalytic mechanism. With multiscale simulations, it was demonstrated that NADH converts directly to NAD(+) via a hydride-transfer reaction during the catalytic cycle. This work provides insight into the mechanism of formate dehydrogenase and highlights the potential of the single-molecule technique in studying NADH/NAD(+)-dependent oxidoreductases.
Article
Nanoscience & Nanotechnology
Liping Zhang, Ya-chao Wang, Yuqi Liao, Qian Zhang, Xia Liu, Dongxia Zhu, Haixing Feng, Martin R. Bryce, Lijie Ren
Summary: This study presents a novel approach for the treatment of ischemic stroke using BDP-4/Cur-CL nanoparticles. These nanoparticles can release visible light signals for real-time monitoring of the progression of ischemia reperfusion brain injury, while also releasing curcumin for safe treatment. The experimental results demonstrate excellent anti-apoptotic and anti-inflammatory effects of this method, effectively improving the cognitive abilities of stroke mice.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Review
Chemistry, Multidisciplinary
Haoran Wang, Qiyao Li, Parvej Alam, Haotian Bai, Vandana Bhalla, Martin R. Bryce, Mingyue Cao, Chao Chen, Sijie Chen, Xirui Chen, Yuncong Chen, Zhijun Chen, Dongfeng Dang, Dan Ding, Siyang Ding, Yanhong Duo, Meng Gao, Wei He, Xuewen He, Xuechuan Hong, Yuning Hong, Jing-Jing Hu, Rong Hu, Xiaolin Huang, Tony D. James, Xingyu Jiang, Gen-ichi Konishi, Ryan T. K. Kwok, Jacky W. Y. Lam, Chunbin Li, Haidong Li, Kai Li, Nan Li, Wei-Jian Li, Ying Li, Xing-Jie Liang, Yongye Liang, Bin Liu, Guozhen Liu, Xingang Liu, Xiaoding Lou, Xin-Yue Lou, Liang Luo, Paul R. McGonigal, Zong-Wan Mao, Guangle Niu, Tze Cin Owyong, Andrea Pucci, Jun Qian, Anjun Qin, Zijie Qiu, Andrey L. Rogach, Bo Situ, Kazuo Tanaka, Youhong Tang, Bingnan Wang, Dong Wang, Jianguo Wang, Wei Wang, Wen-Xiong Wang, Wen-Jin Wang, Xinyuan Wang, Yi-Feng Wang, Shuizhu Wu, Yifan Wu, Yonghua Xiong, Ruohan Xu, Chenxu Yan, Saisai Yan, Hai-Bo Yang, Lin-Lin Yang, Mingwang Yang, Ying-Wei Yang, Juyoung Yoon, Shuang-Quan Zang, Jiangjiang Zhang, Pengfei Zhang, Tianfu Zhang, Xin Zhang, Xin Zhang, Na Zhao, Zheng Zhao, Jie Zheng, Lei Zheng, Zheng Zheng, Ming-Qiang Zhu, Wei-Hong Zhu, Hang Zou, Ben Zhong Tang
Summary: This review provides a comprehensive summary of the applications of aggregation-induced emission (AIE) luminogens in biological imaging, dynamic physiological processes, disease diagnosis and treatment, and specific analyte detection and monitoring. The review also discusses critical issues and future directions, aiming to promote the development of AIE in the fields of life and health.
Article
Chemistry, Inorganic & Nuclear
Ahmed M'hamedi, Andrei S. Batsanov, Mark A. Fox, Juan A. Aguilar, Martin R. Bryce
Summary: Six new diiridium complexes with 2-methyl-6-phenylpyridyl as the cyclometalating ligand and mu(2)-oxamidato or mu(2)-dithioxamidato as the bridging ligand have been synthesized. The presence of multiple isomers in these complexes was confirmed by NMR and X-ray crystallography, and computational calculations supported the experimental findings. The emission spectra of these complexes were attributed to mixed metal-ligand to ligand charge transfer excited states.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY
(2023)
Article
Chemistry, Physical
Rebecca J. Salthouse, Juan Hurtado-Gallego, Iain M. Grace, Ross Davidson, Ohud Alshammari, Nicolas Agrait, Colin J. Lambert, Martin R. Bryce
Summary: We studied a series of thiomethyl anchored cross-conjugated molecules and their skipped-conjugated alcohol derivatives using experimental and theoretical methods. The conductance values of the cross-conjugated molecules and their skipped-conjugated partners were found to be similar. Theoretical studies revealed that the conductance of the alcohol series of compounds varied more with the tilt angle. Thermopower measurements showed that the cross-conjugated ketone molecules had a higher Seebeck coefficient compared to the alcohol derivatives, with a particularly high value for the biphenyl derivative 3a.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Computer Science, Information Systems
Chengdong Ma, Jianan Liu, Saichao He, Wenjing Hong, Jia Shi
Summary: The core technique of unmanned vehicle systems is autonomous maneuvering decision-making, which determines the applications and is a critical technique being developed globally. This paper proposes a novel progressive deep reinforcement learning algorithm for policy optimization in unmanned autonomous decision-making systems.
Article
Chemistry, Inorganic & Nuclear
Shi-Nuo Xu, Yan Zheng, Jing-Yao Ye, Zhong-Yang Chen, Jian-Feng Yan, Yan-Hou Geng, Wenjing Hong, Yao-Feng Yuan
Summary: Here, we present the synthesis, structure, and single-molecule conductance of three o-carborane-based molecular wires with multiple conduction channels. Through experimental and theoretical studies, we found that o-carborane-based wires have a unique three-dimensional structure that facilitates through-space transmission paths and stable molecular junction formation compared to phenyl-centered wires. The significant difference in conductance is attributed to the combination of multiple conduction channels and quantum interference. Understanding the impact of different bridging groups and anchor group substitution patterns provides valuable insights for designing multichannel molecular wires based on o-carboranes.
DALTON TRANSACTIONS
(2023)
Review
Chemistry, Multidisciplinary
Haoran Wang, Qiyao Li, Parvej Alam, Haotian Bai, Vandana Bhalla, Martin R. Bryce, Mingyue Cao, Chao Chen, Sijie Chen, Xirui Chen, Yuncong Chen, Zhijun Chen, Dongfeng Dang, Dan Ding, Siyang Ding, Yanhong Duo, Meng Gao, Wei He, Xuewen He, Xuechuan Hong, Yuning Hong, Jing-Jing Hu, Rong Hu, Xiaolin Huang, Tony D. James, Xingyu Jiang, Gen-ichi Konishi, Ryan T. K. Kwok, Jacky W. Y. Lam, Chunbin Li, Haidong Li, Kai Li, Nan Li, Wei-Jian Li, Ying Li, Xing-Jie Liang, Yongye Liang, Bin Liu, Guozhen Liu, Xingang Liu, Xiaoding Lou, Xin-Yue Lou, Liang Luo, Paul R. McGonigal, Zong-Wan Mao, Guangle Niu, Tze Cin Owyong, Andrea Pucci, Jun Qian, Anjun Qin, Zijie Qiu, Andrey L. Rogach, Bo Situ, Kazuo Tanaka, Youhong Tang, Bingnan Wang, Dong Wang, Jianguo Wang, Wei Wang, Wen-Xiong Wang, Wen-Jin Wang, Xinyuan Wang, Yi-Feng Wang, Shuizhu Wu, Yifan Wu, Yonghua Xiong, Ruohan Xu, Chenxu Yan, Saisai Yan, Hai-Bo Yang, Lin-Lin Yang, Mingwang Yang, Ying-Wei Yang, Juyoung Yoon, Shuang-Quan Zang, Jiangjiang Zhang, Pengfei Zhang, Tianfu Zhang, Xin Zhang, Xin Zhang, Na Zhao, Zheng Zhao, Jie Zheng, Lei Zheng, Zheng Zheng, Ming-Qiang Zhu, Wei-Hong Zhu, Hang Zou, Ben Zhong Tang
Summary: This review provides a comprehensive summary of the advantages and applications of aggregation-induced emission (AIE) luminogens in imaging of biological structure, dynamic physiological processes, disease diagnosis and treatment, as well as detection and monitoring of specific analytes. It also discusses future directions to promote research and development in the fields of life and health.
