Review
Chemistry, Multidisciplinary
Thomas Wloka, Michael Gottschaldt, Ulrich S. Schubert
Summary: This review focuses on the class of two-photon photo initiators (2PI) used for radical polymerization in two-photon polymerization (2PP) technique. It summarizes the absorption behavior, two-photon cross sections, and polymerization efficiency of different 2PIs. Different design approaches are explored to improve the efficiency of 2PIs.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Review
Optics
V. Harinarayana, Y. C. Shin
Summary: With the introduction of femtosecond lasers in the early 1990s, ultrafast laser processing has become crucial for micro/nano machining, with Two-photon lithography (TPL) being a unique technique that has revolutionized laser material processing. This paper provides an overview of TPL, including its working principle, experimental setup, and materials, as well as techniques to improve resolution and pave the way for industrialization. The paper also thoroughly reviews TPL for microfabrication, with an emphasis on metamaterials.
OPTICS AND LASER TECHNOLOGY
(2021)
Article
Materials Science, Multidisciplinary
Egle Ezerskyte, Mikas Vengris, Karolis Gineitis, Greta Merkininkaite, Bettina Leber, Rokas Vargalis, Philipp Stiegler, Peter Schemmer, Simas Sakirzanovas, Aiste Kielaite-Gulla, Kestutis Strupas, Linas Jonusauskas
Summary: Femtosecond laser-based two-photon polymerization is popular in biofabrication for its ability to use various materials to produce biology-oriented structures. This study compares the structurability and biocompatibility of popular pre-polymers, such as SZ2080, SU8, and GelMA, using different photoinitiators and wavelengths. Two-photon absorption measurement provides insights into the efficiency of the photopolymerization process. Surprisingly, there are small differences in biocompatibility among the tested materials.
OPTICAL MATERIALS EXPRESS
(2022)
Review
Biotechnology & Applied Microbiology
Xian Jing, Hongxun Fu, Baojun Yu, Meiyan Sun, Liye Wang
Summary: The use of two-photon polymerization (TPP) as an advanced manufacturing technique for complex 3D biomedical scaffold fabrication is discussed in this review. TPP has the ability to fabricate structures with high resolution and mimic the microenvironment of natural extracellular matrix, making it suitable for cell culture and tissue engineering. The review covers various perspectives and principles from physics, materials science, chemistry, biomedicine, and mechanical engineering.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Polymer Science
Shixiong Chen, Chun Cao, Xiaoming Shen, Yiwei Qiu, Cuifang Kuang, Decheng Wan, Ming Jin
Summary: Three sulfonium salt photoinitiators based on 1,3,5-triphenyl-2-pyrazoline were synthesized, and their molecular structures, photophysical and photochemical properties under one/two-photon irradiation were investigated. The study revealed their potential applications in LED photocuring and two-photon 3D microfabrication.
EUROPEAN POLYMER JOURNAL
(2021)
Article
Engineering, Manufacturing
Federico Cantoni, Daniel Maher, Eugenia Bosler, Stefan Kuhne, Laurent Barbe, Dirk Oberschmidt, Christophe Marquette, Rafael Taboryski, Maria Tenje, Ada- Ioana Bunea
Summary: Since its introduction in the 1980s, 3D printing has developed as a versatile and reliable tool with applications in different fields. Among these, two-photon polymerization is considered one of the most promising technologies due to its ability to achieve high precision printing down to submicron scale and free-form structure design. Recent advancements in faster laser scanning strategies and new photoresists have further enhanced this technology, leading to a wider range of applications. This study aims to provide an overview of the technology capability by comparing three commercial systems in a round-robin test.
ADDITIVE MANUFACTURING
(2023)
Article
Polymer Science
Martyna Durko-Maciag, Gilles Ulrich, Julien Massue, Jaroslaw Mysliwiec, Konrad Cyprych
Summary: This work demonstrates the successful application of Excited-State Intramolecular Proton Transfer (ESIPT) fluorophores as photoinitiators for microfabrication. The influence of chemical structure on this application was investigated, followed by analysis of two-photon polymerization. The study determined the quality of fabricated structures and polymerization thresholds, with one of the chromophores having an impressively low value of 11 nJ.
EUROPEAN POLYMER JOURNAL
(2023)
Article
Optics
Jason E. Johnson, Yijie Chen, Xianfan Xu
Summary: A mathematical model is developed to describe the photochemical processes in two-photon nanolithography. The model provides insights into the dominant factors and sensitivities of the process parameters, such as diffusion of photoinitiators and oxygen inhibitors, and the effect of self-deactivation on the effective nonlinearity in two-photon nanolithography.
Article
Chemistry, Multidisciplinary
Frank Marco den Hoed, Andrea Ottomaniello, Omar Tricinci, Luca Ceseracciu, Marco Carlotti, Patrizio Raffa, Virgilio Mattoli
Summary: This study presents a novel technique for the realization of 3D micro-structures on complex surfaces with high conformability. The method involves two-photon polymerization of micro-structures on polymeric nano-membranes, which can be efficiently transferred to a target surface. Ultra-thin polymeric films are used as support to suspend and transfer the printed micro-structures. The technique offers flexibility in choice of structures, materials, transfer procedures, and substrate geometries.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Seyyedhossien Mckee, Adrian Lutey, Corrado Sciancalepore, Federica Poli, Stefano Selleri, Annamaria Cucinotta
Summary: This paper presents the development of 3D solid microneedle arrays as a novel transdermal drug delivery system using two-photon polymerization. Through experiments and simulations, the influence of fabrication parameters on the structural resolution of microneedles and the deformation of human skin is studied.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
(2022)
Article
Chemistry, Multidisciplinary
Brandon J. Furey, Benjamin J. Stacy, Tushti Shah, Rodrigo M. Barba-Barba, Ramon Carriles, Alan Bernal, Bernardo S. Mendoza, Brian A. Korgel, Michael C. Downer
Summary: Colloidal nanocrystalline silicon quantum dots (nc-SiQDs) excited by two-photon in the near-infrared (NIR) range have potential applications in deep biological imaging. The two-photon absorption (2PA) cross section of colloidal nc-SiQDs is measured, and it is found to be smaller for smaller diameter nanocrystals. The efficiencies of nc-SiQDs for bioimaging using two-photon excited photoluminescence (2PE-PL) are compared to other quantum dots and molecular fluorophores and found to be comparable or superior at greater depths.
Article
Materials Science, Multidisciplinary
Dingdong Zhang, Guillermo Lopez-Quesada, Samuel Bergdolt, Stefan Hengsbach, Klaus Bade, Stephane Colin, Marcos Rojas-Cardenas
Summary: The two-photon-polymerization (TPP) fabrication technique was used to create three-dimensional micro-structures for rarefied gas flows. The geometry of the micro-tubes was characterized using various measurement techniques. Experimental measurements of nitrogen gas flow rates were compared to theoretical values, and the results showed good agreement. This study demonstrates the feasibility of using TPP fabrication technique to create well controlled 3D microsystems for rarefied gas flows applications.
Article
Chemistry, Physical
Xinyue Wang, Di Wang, Jia Li, Meixia Zhang, Peng Song
Summary: The theoretical study investigated the photoinduced charge transfer process of D-D-pi-A molecules, showing red shift in absorption spectrum and increased absorption intensity due to donor insertion. Visualization method was used to observe charge transfer in one- and two-photon absorption processes, with the thiazolo[5,4-d]thiazole donor insertion showing the largest TPA cross-section. This work contributes to understanding D-D-pi-A molecules and designing molecules with large cross-section TPA properties.
Article
Engineering, Manufacturing
Caroline Arnoux, Luis A. Perez-Covarrubias, Alexandre Khaldi, Quentin Carlier, Patrice L. Baldeck, Kevin Heggarty, Akos Banyasz, Cyrille Monnereau
Summary: This paper investigates the proximity effects in additive manufacturing and proposes a parallel write approach to overcome the limitations caused by these effects. Through experiments and computer simulations, the authors successfully model the effects and demonstrate the effectiveness of the parallel write approach in fabricating structures with submicronic inter-object distances.
ADDITIVE MANUFACTURING
(2022)
Article
Materials Science, Multidisciplinary
Teng Chi, Paul Somers, Daniel A. Wilcox, Ashley J. Schuman, Jason E. Johnson, Zihao Liang, Liang Pan, Xianfan Xu, Bryan W. Boudouris
Summary: ITX is a common photoinitiator in DLW polymerization processes due to its high-efficiency photoinitiating abilities. However, improved photoinitiating materials are required for advanced high-throughput nanomanufacturing techniques. Thioxanthone-based photoinitiators with tailored optical and charge transfer properties were designed and synthesized to demonstrate enhanced two-photon polymerization DLW for superresolution properties.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Chemistry, Physical
Adrien Bourdolle, Anthony D'Aleo, Cecile Philippot, Patrice L. Baldeck, Yannick Guyot, Fabien Dubois, Alain Ibanez, Chantal Andraud, Sophie Brasselet, Olivier Maury
Article
Chemistry, Analytical
Chih-Lang Lin, Yu-Sheng Lin, Patrice L. Baldeck
Article
Materials Science, Multidisciplinary
Monica Focsan, Ana Maria Craciun, Simion Astilean, Patrice L. Baldeck
OPTICAL MATERIALS EXPRESS
(2016)
Article
Materials Science, Multidisciplinary
Martin Ipuy, Yuan-Yuan Liao, Erwann Jeanneau, Patrice L. Baldeck, Yann Bretonniere, Chantal Andraud
JOURNAL OF MATERIALS CHEMISTRY C
(2016)
Article
Nanoscience & Nanotechnology
Yi-Jui Liu, Juin-Yi Yang, Yung-Mau Nie, Chun-Hung Lu, Eric Dowkon Huang, Chow-Shing Shin, Patrice Baldeck, Chih-Lang Lin
MICROFLUIDICS AND NANOFLUIDICS
(2015)
Article
Engineering, Chemical
Chow-Shing Shin, Patrice L. Baldeck, Yung-Mau Nie, Yi-Hsiung Lee, Zheng-Da Lin, Chia-Chin Chiang, Chih-Lang Lin
Summary: A single 3D multi-manifold micromixer composed of a double Archimedes screw was developed for rapidly mixing within a short distance; Numerical simulations showed satisfactory mixing efficiency can be achieved at a distance of approximately twice the microchannel width; Experimental demonstration by an ASM fabricated by two-photon stereolithography showed good agreement with simulation findings.
JOURNAL OF THE TAIWAN INSTITUTE OF CHEMICAL ENGINEERS
(2021)
Article
Chemistry, Multidisciplinary
Anne Desponds, Akos Banyasz, Denis Chateau, Azeddine Tellal, Amandine Venier, Sylvain Meille, Gilles Montagnac, Jerome Chevalier, Chantal Andraud, Patrice L. Baldeck, Stephane Parola
Summary: An original approach based on a composite resin incorporating ultrasmall zirconia nanoparticles is proposed to process 3D zirconia microstructures with high spatial resolution, limiting the shrinkage issue during debinding/sintering. The nanoparticles act as seeds for controlling crystallographic phase formation and as structural stabilizing agents, resulting in stable 3D microstructures of cubic zirconia with reduced weight and volume loss. The technology also allows for the creation of microfocusing and microlens array with high diffraction efficiency.
Article
Engineering, Manufacturing
Caroline Arnoux, Luis A. Perez-Covarrubias, Alexandre Khaldi, Quentin Carlier, Patrice L. Baldeck, Kevin Heggarty, Akos Banyasz, Cyrille Monnereau
Summary: This paper investigates the proximity effects in additive manufacturing and proposes a parallel write approach to overcome the limitations caused by these effects. Through experiments and computer simulations, the authors successfully model the effects and demonstrate the effectiveness of the parallel write approach in fabricating structures with submicronic inter-object distances.
ADDITIVE MANUFACTURING
(2022)
Article
Chemistry, Analytical
Chih-Lang Lin, Shyang-Guang Wang, Meng-Tsung Tien, Chung-Han Chiang, Yi-Chieh Lee, Patrice L. Baldeck, Chow-Shing Shin
Summary: This paper presents a novel methodology for detecting variations in cell surface antigens through optical cell-tearing and dilution regulations. The study found that higher dilution required lower power to tear off the cell binding, indicating antigenic variation. The proposed relative-quantitative analysis theory can provide an intuitive estimation of antigenic variation.
Article
Optics
Azeddine Tellal, Omar Ziane, Patrice L. Baldeck
CHINESE OPTICS LETTERS
(2019)
Article
Nanoscience & Nanotechnology
Azeddine Tellal, Omar Ziane, Safi Jradi, Olivier Stephan, Patrice L. Baldeck
Proceedings Paper
Engineering, Biomedical
Chih-Lang Lin, Yi-Jui Liu, Zheng-Da Lin, Bo-Long Wu, Yi-Hsiung Lee, Chow-Shing Shin, Patrice L. Baldeck
MICROFLUIDICS, BIOMEMS, AND MEDICAL MICROSYSTEMS XIII
(2015)
Proceedings Paper
Nanoscience & Nanotechnology
Chih-Lang Lin, Ming-Jeng Pan, Hai-Wen Chen, Che-Kuan Lin, Chuen-Fu Lin, Patrice L. Baldeck
FRONTIERS IN BIOLOGICAL DETECTION: FROM NANOSENSORS TO SYSTEMS VII
(2015)
Proceedings Paper
Engineering, Electrical & Electronic
Taghrid Mhalla, Patrice L. Baldeck
LASER-BASED MICRO- AND NANOPROCESSING VIII
(2014)
Proceedings Paper
Nanoscience & Nanotechnology
P. L. Baldeck, J. Navarro, G. Micouin, A-M Gabudean, F. Lerouge, C. Monnerau, F. Chaput, C. Andraud, S. Parola
REPORTERS, MARKERS, DYES, NANOPARTICLES, AND MOLECULAR PROBES FOR BIOMEDICAL APPLICATIONS VI
(2014)