Enantioseparation on Helical Poly(phenylacetylene)s Bearing Cinchona Alkaloid Pendants as Chiral Stationary Phases for HPLC

A series of optically active helical poly(phenylacetylene)s bearing cinchona alkaloid pendant groups was coated on macroporous silica gel to obtain novel chiral packing materials for high-performance liquid chromatography, which could resolve diverse racemic compounds into enantiomers whose chiral recognition abilities were significantly influenced by the macromolecular helicity induced by the alkaloid pendants.