期刊
CHEMISTRY LETTERS
卷 41, 期 3, 页码 262-263出版社
CHEMICAL SOC JAPAN
DOI: 10.1246/cl.2012.262
关键词
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资金
- Japan Science and Technology Agency
- Grants-in-Aid for Scientific Research [23310157, 23500511] Funding Source: KAKEN
Organelle-selective oxygen probe BTP-Mito was designed and synthesized to selectively target mitochondria. BTP-Mito, which is an iridium complex bearing a triphenylphosphonium cation, exhibited selective mitochondria localization in HeLa cells. The phosphorescence of BTP-Mito was significantly quenched by molecular oxygen in living cells, demonstrating that BTP-Mito can be used as mitochondria-specific oxygen sensor.
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