α-Amidobenzylation of Aryl and Alkenyl Halides via Palladium-catalyzed Suzuki-Miyaura Coupling with α-(Acylamino)benzylboronic Esters

The Suzuki-Miyaura coupling of alpha-(acetylatnino)benzyl-boronic esters with aryl and alkenyl halides has been achieved using a Pd/P(t-Bu)(3) catalyst with KF and H2O in 1,4-dioxane, giving a-substituted benzylamines in high yields.