Review
Nutrition & Dietetics
Yabin Zhou, Jin Hua, Zhiguo Huang
Summary: Non-alcoholic fatty liver disease (NAFLD) is a common cause of chronic liver disease, affecting approximately 24% of the global population. This study aims to evaluate the effects of alcoholic beverages, including beer, wine, and Chinese baijiu, on NAFLD and hepatic lipid metabolism. While there is some evidence suggesting potential beneficial effects, such as antioxidative properties, inconsistent data exist and further research is needed. Specifically, the effects of baijiu on NAFLD are understudied, and it remains unclear whether the antioxidative effects of bioactive flavor compounds can outweigh the oxidative stress and toxic effects of the ethanol component.
FRONTIERS IN NUTRITION
(2023)
Review
Chemistry, Analytical
Daniel Schorn-Garcia, Julieta Cavaglia, Barbara Giussani, Olga Busto, Laura Acena, Montserrat Mestres, Ricard Boque
Summary: This article guides readers on monitoring fermentation using ATR-MIR spectroscopy and chemometric techniques, emphasizing the importance of sampling for modeling, providing methods for setting parameter for good signal quality, and explaining data preparation and calculations. The modeling strategies utilizing basic chemometric tools are effective and affordable for both experts and non-experts.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Vanpaseuth Phouthavong, Hayato Inoue, Kesiny Phomkeona, Vanseng Chounlamany
Summary: This work utilized a membraneless vaporization unit for the colorimetric determination of ethanol in alcoholic beverages, providing a simple and accurate method for quantifying ethanol content.
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2022)
Article
Chemistry, Analytical
Vanpaseuth Phouthavong, Hayato Inoue, Kesiny Phomkeona, Vanseng Chounlamany
Summary: This study utilized a membraneless vaporization unit for the colorimetric determination of ethanol in alcoholic beverages. The method is simple, accurate, and has good applicability to different types of beverages.
JOURNAL OF ANALYTICAL METHODS IN CHEMISTRY
(2022)
Article
Food Science & Technology
Agnieszka Micek, Justyna Godos, Achille Cernigliaro, Raffaele Ivan Cincione, Silvio Buscemi, Massimo Libra, Fabio Galvano, Giuseppe Grosso
Summary: The intake of polyphenol-rich beverages is associated with metabolic status, with individuals consuming more of these beverages less likely to have hypertension, type 2 diabetes, and dyslipidemia, particularly with a significant association with hypertension. Current scientific evidence suggests that such beverages may have a positive impact on cardio-metabolic risk factors.
Article
Chemistry, Applied
Olga Wachelko, Pawel Szpot, Marcin Zawadzki
Summary: The study focused on the determination of ethyl alcohol concentration in alcoholic beverages, confirming the accuracy and reliability of headspace gas chromatography. Trace quantities of volatile compounds and fusel alcohols were found in the majority of alcoholic beverages.
Article
Chemistry, Applied
A. C. C. Fulgencio, Glaucimar Alex Passos Resende, Marden Claret Fontoura Teixeira, Bruno Gonsalves Botelho, Marcelo Martins Sena
Summary: In this study, a rapid detection method for DEG in beer samples was developed using portable near-infrared spectroscopy combined with partial least squares discriminant analysis (PLS-DA). The method was validated and shown to be effective and feasible.
Article
Food Science & Technology
Agnieszka Micek, Ali A. Alshatwi, Nadia Paladino, Ida Guerrera, Giuseppe Grosso, Sabrina Castellano, Justyna Godos
Summary: Research suggests that consuming plant-based foods and beverages rich in (poly)phenols may play a role in preventing cognitive disorders. This study examined the association between the consumption of (poly)phenol-rich beverages, such as wine and beer, resveratrol intake, and cognitive status in older adults. The findings showed that higher consumption of red wine was associated with lower odds of cognitive impairment, while only the highest intake of white wine was linked to lower odds of cognitive impairment. No significant results were found for beer intake. Higher resveratrol intake was also associated with lower odds of cognitive impairment. In conclusion, consuming (poly)phenol-rich beverages may have a positive impact on cognition in older adults.
INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
(2023)
Article
Chemistry, Applied
Juliana Milheiro, Fernanda Cosme, Luis Filipe-Ribeiro, Fernando M. Nunes
Summary: A simple, fast, and robust method was developed for determining pyruvic acid, acetaldehyde, and alpha-ketobutyric acid in Port wines, dry table wines, and wine spirits. The method involves reductive amination of aldehyde 2,4-dinitrophenylhydrazones using cyanoborohydride followed by HPLC-DAD analysis. The method showed good performance in several parameters and enables simultaneous quantification of these carbonyl compounds in Port wines for the first time.
Article
Food Science & Technology
Ana Carolina da Costa Fulgencio, Glaucimar Alex Passos Resende, Marden Claret Fontoura Teixeira, Bruno Goncalves Botelho, Marcelo Martins Sena
Summary: This study proposed and validated a new rapid and direct multivariate method for determining alcohol content in beers using a portable NIR spectrometer and PLS regression. The method was demonstrated to be accurate and applicable to a variety of beers from different styles, brands, and breweries.
FOOD ANALYTICAL METHODS
(2022)
Article
Chemistry, Analytical
Chaoqi Wang, Yitao Lv, Xueyin Hu, Zhifei Chen, Juxiu Li, Min Zhang
Summary: This study developed a two-step assay using non-advanced materials for the detection of methylglyoxal (MGO). The effect of electrode electro-activation on the composition changes of the GCE surface and MGO detection was investigated. The MGO detection signal was enhanced through background subtraction and pH adjustment.
ANALYTICA CHIMICA ACTA
(2022)
Article
Biochemical Research Methods
P. Layton Ashmore, Florentino Valdez, James F. Harbertson, Roger B. Boulton, Thomas S. Collins
Summary: A novel method using CE-UV/vis was developed for the determination of free SO2 in wine and cider. The CE method showed significant differences with conventional methods, especially in the presence of anthocyanins. The CE method was found to be rapid, sensitive, robust, and repeatable, overcoming the issue of over-reporting free SO2 in pigmented samples.
JOURNAL OF CHROMATOGRAPHY A
(2023)
Article
Chemistry, Analytical
M. Asuncion Alonso-Lomillo, Olga Dominguez-Renedo
Summary: This work presents a molecularly imprinted (MIP) sensor for the determination of ethanethiol. The MIP/GCE sensor showed a linear range of 6.1-32.4 mg L-1 with good detection capability and reproducibility. The sensitivity of the sensor was enhanced by incorporating gold nano-particles. The sensor was successfully applied to determine ethanethiol in spiked wine samples.
Article
Chemistry, Analytical
Shan Chen, Jinli Fu, Shu Zhou, Xiaodan Wu, Sisi Tang, Pengfei Zhao, Zhaohui Zhang
Summary: An eco-friendly molecularly imprinted fluorescence sensor utilizing novel NIR fluorescence carbon dots and metal-organic frameworks was developed for the rapid determination of trypsin. The sensor showed improved sensitivity and response speed with the introduction of zeolite imidazolate framework-8. The sensor exhibited a linear relationship between fluorescence quenching and trypsin concentration with a detection limit of 8.8 pg/L, providing a viable method for sensitive detection in complex samples.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Phennapa Khanaaekwichaporn, Chongdee Thammakhet-Buranachai, Warawut Sangsudcha, Panote Thavarungkul, Proespichaya Kanatharana, Itthipon Jeerapan
Summary: This study reports the application of copper-based nanoparticles synthesized via green synthesis and their integration with a wearable electrode for designing a flexible catalytic electrode on a glove. The developed lab-on-a-finger sensor enables fast electroanalysis of paraquat within 10 seconds, with a wide range of detection from 0.50 to 1000 μM and a low detection limit of 0.31 μM. The wearable glove sensor allows direct touch and analysis of samples for on-site analysis of food contamination and environments.
Review
Substance Abuse
Juergen Rehm, Maria Neufeld, Robin Room, Bundit Sornpaisarn, Mindaugas Stelemekas, Monica H. Swahn, Dirk W. Lachenmeier
Summary: This study examines whether increases in taxation have led to increases in consumption of unrecorded alcohol and highlights that the level of unrecorded consumption depends on various factors. Mitigation strategies to reduce unrecorded alcohol use are also outlined.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2022)
Article
Food Science & Technology
Hannah Draeger, Ines Barthlott, Patricia Golombek, Stephan G. Walch, Dirk W. Lachenmeier
Summary: This article provides an overview of the THC content in hemp food products in Germany in recent years. Hemp beverages and seeds typically do not contain amounts of THC that can exceed toxicological thresholds, while hemp food supplements, such as CBD products, can contain high levels of THC. The THC content of hemp food supplements showed a significant linear decrease between 2018 and 2021. Tea based on flowers emerged as a problematic food group, leading to an increase in overall THC levels. Regulating low-THC products within the framework of controlled distribution of cannabis for recreational use appears to be advisable.
Article
Food Science & Technology
Dirk W. Lachenmeier, Paula A. Oliveira, Agata Urszula Fabiszewska, Cristina Maria Dias Soares, Jong H. Kim
Summary: This article summarizes a conference session that aimed to bring together international experts in food toxicology and food safety to share scientific knowledge. The presentations covered a wide range of interdisciplinary issues, including the impact of diet on health outcomes, methods for microbial oil extraction, food processing and its effects on safety and health, avoiding mycotoxin contamination, and the safety of cannabidiol in food supplements. Conclusions from the presentations showed that food choices can affect the risk of non-communicable diseases, food processing can have both positive and negative effects on health, and research on novel compounds is important for prevention and health.
Review
Food Science & Technology
Sabine Guth, Matthias Baum, Alexander T. Cartus, Patrick Diel, Karl-Heinz Engel, Barbara Engeli, Bernd Epe, Tilman Grune, Dirk Haller, Volker Heinz, Michael Hellwig, Jan G. Hengstler, Thomas Henle, Hans-Ulrich Humpf, Henry Jaeger, Hans-Georg Joost, Sabine E. Kulling, Dirk W. Lachenmeier, Alfonso Lampen, Marcel Leist, Angela Mally, Doris Marko, Ute Noethlings, Elke Roehrdanz, Angelika Roth, Joachim Spranger, Richard Stadler, Pablo Steinberg, Stefan Vieths, Wim Waetjen, Gerhard Eisenbrand
Summary: This opinion from the SKLM presents arguments for an updated risk assessment of acrylamide (AA) exposure in diet, based on a critical review of relevant scientific evidence. The SKLM concludes that as long as exposure limits for AA are not exceeded, genotoxic effects leading to carcinogenicity are unlikely to occur. Considering the totality of evidence, the SKLM deems it scientifically justified to establish a tolerable daily intake (TDI) as a health-based guidance value.
FOOD AND CHEMICAL TOXICOLOGY
(2023)
Review
Biochemistry & Molecular Biology
Nick Konstantinidis, Heike Franke, Steffen Schwarz, Dirk W. Lachenmeier
Summary: Trigonelline is a bioactive pyridine alkaloid found in high concentrations in coffee and coffee by-products. The use of coffee by-products as food has gained interest due to their economic and nutritional value and environmental benefits. This review aimed to assess the risk of acute and chronic exposure to trigonelline from coffee and coffee by-products on human health. Limited toxicological knowledge and a lack of human data make it difficult to draw conclusions. However, trigonelline ingested as part of coffee and coffee by-products appears to be safe based on their traditional use.
Article
Food Science & Technology
Sydney Schorb, Katharina Gleiss, Roland Wedekind, Eero Suonio, Ann-Kathrin Kull, Marcel Kuntz, Stephan G. Walch, Dirk W. Lachenmeier
Summary: This study analyzes the presence of the artificial sweetener aspartame (E951) in German foods and beverages from 2000 to 2022. Among 53,116 samples, aspartame was detected in 14% and further evaluated in nine major food groups. Aspartame was most commonly found in powdered drink bases, flavored milk drinks, chewing gum, and diet soft drinks. The levels of aspartame detected generally comply with the legal limits set by the European Union.
Review
Food Science & Technology
Constanze Sproll, Stephan G. Walch, Dirk W. Lachenmeier
Summary: The precautionary principle is an important concept in EU law, particularly in relation to food control. However, it has not received enough attention in practice. This article examines the application of the precautionary principle in the context of products containing CBD, and concludes that authorities can take additional protective measures based on this principle.
JOURNAL OF CONSUMER PROTECTION AND FOOD SAFETY
(2023)
News Item
Oncology
Elio Riboli, Frederick A. Beland, Dirk W. Lachenmeier, M. Matilde Marques, David H. Phillips, Eva Schernhammer, Abdul Afghan, Ricardo Assuncao, Giovanna Caderni, J. Christopher Corton, Gisela de Aragao Umbuzeiro, Daphne de Jong, Melanie Deschasaux- Tanguy, Allison Hodge, Junko Ishihara, Dan D. Levy, Daniele Mandrioli, Marjorie L. Mccullough, Sarah A. Mcnaughton, Takeshi Morita, Anne P. Nugent, Kumiko Ogawa, Arun R. Pandiri, Consolato M. Sergi, Mathilde Touvier, Luoping Zhang, Lamia Benbrahim- Tallaa, Shirisha Chittiboyina, Danila Cuomo, Nathan L. Debono, Charlotte Debras, Aline de Conti, Fatiha El Ghissassi, Emma Fontvieille, Rhea Harewood, John Kaldor, Heidi Mattock, Elisa Pasqual, Gabrielle Rigutto, Hannah Simba, Eero Suonio, Susana Viegas, Roland Wedekind, Mary K. Schubauer-Berigan, Federica Madia
Review
Food Science & Technology
Alexander Cartus, Dirk Lachenmeier, Sabine Guth, Angelika Roth, Matthias Baum, Patrick Diel, Gerhard Eisenbrand, Barbara Engeli, Michael Hellwig, Hans-Ulrich Humpf, Hans-Georg Joost, Sabine Kulling, Alfonso Lampen, Doris Marko, Pablo Steinberg, Wim Waetjen, Jan Hengstler, Angela Mally
Summary: The Senate Commission on Food Safety has found that the use of acetaldehyde as a flavoring substance in foods may pose health risks due to its genotoxic potential. However, there is a lack of sufficient data to determine its genotoxic effects in vivo after oral exposure. Therefore, the commission recommends reassessing the safety of using acetaldehyde as a food flavoring.
MOLECULAR NUTRITION & FOOD RESEARCH
(2023)
Review
Biochemistry & Molecular Biology
Sascha Behne, Heike Franke, Steffen Schwarz, Dirk W. Lachenmeier
Summary: Chlorogenic and isochlorogenic acids, found in plants, fruits, vegetables, coffee, and coffee by-products, are natural antioxidant compounds. This review aimed to assess the potential health risks of consuming coffee by-products containing these acids. Literature research revealed the major chlorogenic acids in coffee by-products. Studies on animals and humans indicated no significant toxic effects following acute exposure, suggesting long-term consumption of chlorogenic and isochlorogenic acids from coffee by-products is not a health risk.
Review
Biochemistry & Molecular Biology
Patricia Fels, Dirk W. Lachenmeier, Pascal Hindelang, Stephan G. Walch, Birgit Gutsche
Summary: This literature review focuses on the analysis of organic and inorganic contaminants in tattoo inks prior to the implementation of the REACH regulation in 2022. Polycyclic aromatic hydrocarbons (PAHs) and primary aromatic amines (PAAs) were found to be the most common contaminants, with the presence of heavy metals such as lead and chromium(VI) detected in almost all tattoo inks. However, the limited quantitative data on contaminants in tattoo inks and the potential changes in ink composition due to the implementation of REACH pose limitations to the results of this review.
Review
Chemistry, Analytical
Thomas Kuballa, Katja H. Kaltenbach, Jan Teipel, Dirk W. Lachenmeier
Summary: This review assesses the current state of implementing liquid NMR in the food, cosmetics, and pharmaceutical industries, highlighting its transformation from a structural elucidation tool to a widely recognized multi-analytical method that incorporates multivariate techniques.
Article
Chemistry, Applied
Vera Gottstein, Dirk W. Lachenmeier, Thomas Kuballa, Mirko Bunzel
Summary: A comprehensive study utilizing NMR fingerprinting and multivariate data analysis was conducted on 603 roasted arabica coffee samples. The results showed that the coffee samples could be differentiated based on their geographical origin, but differentiation between organically and conventionally produced coffee samples was not achieved.
Meeting Abstract
Toxicology
C. Kalisch, M. Reiter, M. Krieger, L. Wuest, B. Saenger, R. Dekant, D. W. Lachenmeier, O. Scherf-Clavel, A. Mally
TOXICOLOGY LETTERS
(2023)
Article
Chemistry, Multidisciplinary
Jan Teipel, Vera Gottstein, Eva Hoelzle, Katja Kaltenbach, Dirk W. Lachenmeier, Thomas Kuballa
Summary: Highly reactive decomposition products of deuterated chloroform can cause irreversible impact on samples dissolved in this commonly used solvent for NMR spectroscopy, resulting in inaccurate results for non-targeted analysis methods. To prevent this, chlorine, phosgene and hydrochloric acid should be eliminated from deuterated chloroform before use. Another purification method tested is washing the deuterated chloroform with concentrated disodium carbonate solution and subsequent desiccation.
CHEMISTRY-SWITZERLAND
(2022)