Roles of palmitoylation and the KIKK membrane-targeting motif in leukemogenesis by oncogenic KRAS4A

KRAS as a Therapeutic Target

(2015) F. McCormick   CLINICAL CANCER RESEARCH

Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?

(2015) A. D. Cox et al.   CLINICAL CANCER RESEARCH

Mechanisms of Membrane Binding of Small GTPase K-Ras4B Farnesylated Hypervariable Region

(2015) Hyunbum Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

K-Ras4A splice variant is widely expressed in cancer and uses a hybrid membrane-targeting motif

(2015) Frederick D. Tsai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strategies for modern biomarker and drug development in oncology

(2014) Alan D Smith et al.   Journal of Hematology & Oncology

MicroRNA-mediated regulation of KRAS in cancer

(2014) Minlee Kim et al.   Journal of Hematology & Oncology

Drugging the undruggable RAS: Mission Possible?

(2014) Adrienne D. Cox et al.   NATURE REVIEWS DRUG DISCOVERY

Mixed lineage kinases activate MEK independently of RAF to mediate resistance to RAF inhibitors

(2014) Anna A. Marusiak et al.   Nature Communications

A Genome-Wide Aberrant RNA Splicing in Patients with Acute Myeloid Leukemia Identifies Novel Potential Disease Markers and Therapeutic Targets

(2013) Sophia Adamia et al.   CLINICAL CANCER RESEARCH

Alternative Splicing in Chronic Myeloid Leukemia (CML): A Novel Therapeutic Target?

(2013) Sophia Adamia et al.   CURRENT CANCER DRUG TARGETS

Phosphatidylinositol 3-kinase (PI3K) inhibitors as cancer therapeutics

(2013) Akintunde Akinleye et al.   Journal of Hematology & Oncology

MEK and the inhibitors: from bench to bedside

(2013) Akintunde Akinleye et al.   Journal of Hematology & Oncology

B-Raf and the inhibitors: from bench to bedside

(2013) Tiangui Huang et al.   Journal of Hematology & Oncology

Palmitoylation of oncogenic NRAS is essential for leukemogenesis

(2010) B. Cuiffo et al.   BLOOD

Raf-independent, PP2A-dependent MEK activation in response to ERK silencing

(2009) Dongsoon Bae et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Palmitoylation and localisation of RAS isoforms are modulated by the hypervariable linker domain

(2008) Alex J. Laude et al.   JOURNAL OF CELL SCIENCE

Kras regulatory elements and exon 4A determine mutation specificity in lung cancer

(2008) Minh D To et al.   NATURE GENETICS

Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis

(2007) Charles E. Patek et al.   EXPERIMENTAL CELL RESEARCH