Identification of plasma microRNA profiles for primary resistance to EGFR-TKIs in advanced non-small cell lung cancer (NSCLC) patients with EGFR activating mutation

Strategies for modern biomarker and drug development in oncology

(2014) Alan D Smith et al.   Journal of Hematology & Oncology

Functions of lncRNA HOTAIR in lung cancer

(2014) Gregory Loewen et al.   Journal of Hematology & Oncology

Circulating miRNAs in cancer: from detection to therapy

(2014) Wen-Tao Wang et al.   Journal of Hematology & Oncology

Notch signaling and EMT in non-small cell lung cancer: biological significance and therapeutic application

(2014) Xun Yuan et al.   Journal of Hematology & Oncology

Effectiveness of Gefitinib against Non–Small-Cell Lung Cancer with the Uncommon EGFR Mutations G719X and L861Q

(2014) Satoshi Watanabe et al.   Journal of Thoracic Oncology

AZD9291, an Irreversible EGFR TKI, Overcomes T790M-Mediated Resistance to EGFR Inhibitors in Lung Cancer

(2014) D. A. E. Cross et al.   Cancer Discovery

Primary resistance to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in patients with non-small-cell lung cancer harboring TKI-sensitive EGFR mutations: an exploratory study

(2013) J. K. Lee et al.   ANNALS OF ONCOLOGY

EGFR-TKI Resistance Due to BIM Polymorphism Can Be Circumvented in Combination with HDAC Inhibition

(2013) T. Nakagawa et al.   CANCER RESEARCH

Induction of long intergenic non-coding RNA HOTAIR in lung cancer cells by type I collagen

(2013) Yan Zhuang et al.   Journal of Hematology & Oncology

Long non-coding RNA: a new player in cancer

(2013) Hua Zhang et al.   Journal of Hematology & Oncology

Inhibition of Hedgehog signaling sensitizes NSCLC cells to standard therapies through modulation of EMT-regulating miRNAs

(2013) Aamir Ahmad et al.   Journal of Hematology & Oncology

MiR-21 overexpression is associated with acquired resistance of EGFR-TKI in non-small cell lung cancer

(2013) Bing Li et al.   LUNG CANCER

The prognostic impact of microRNA sequence polymorphisms on the recurrence of patients with completely resected non–small cell lung cancer

(2012) Kyong-Ah Yoon et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Correction: Serum microRNA Biomarkers for Detection of Non-Small Cell Lung Cancer

(2012) Patrick T. Hennessey et al.   PLoS One

Crizotinib-Resistant Mutants of EML4-ALK Identified Through an Accelerated Mutagenesis Screen

(2011) Sen Zhang et al.   Chemical Biology & Drug Design

A serum circulating miRNA diagnostic test to identify asymptomatic high-risk individuals with early stage lung cancer

(2011) Fabrizio Bianchi et al.   EMBO Molecular Medicine

Erlotinib versus chemotherapy as first-line treatment for patients with advanced EGFR mutation-positive non-small-cell lung cancer (OPTIMAL, CTONG-0802): a multicentre, open-label, randomised, phase 3 study

(2011) Caicun Zhou et al.   LANCET ONCOLOGY

MicroRNA signatures in tissues and plasma predict development and prognosis of computed tomography detected lung cancer

(2011) Mattia Boeri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of microRNA-21 in mediating chemo-resistance to docetaxel in androgen-independent prostate cancer PC3 cells

(2010) Guo-hai Shi et al.   ACTA PHARMACOLOGICA SINICA

MicroRNA-21 inhibitor sensitizes human glioblastoma cells U251 (PTEN-mutant) and LN229 (PTEN-wild type) to taxol

(2010) Yu Ren et al.   BMC CANCER

MiR-21 protected human glioblastoma U87MG cells from chemotherapeutic drug temozolomide induced apoptosis by decreasing Bax/Bcl-2 ratio and caspase-3 activity

(2010) Lei Shi et al.   BRAIN RESEARCH

MicroRNA-21 in Pancreatic Cancer: Correlation with Clinical Outcome and Pharmacologic Aspects Underlying Its Role in the Modulation of Gemcitabine Activity

(2010) Elisa Giovannetti et al.   CANCER RESEARCH

Plasma microRNAs as potential biomarkers for non-small-cell lung cancer

(2010) Jun Shen et al.   LABORATORY INVESTIGATION

miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation

(2009) Michela Garofalo et al.   CANCER CELL

Clinical Features and Outcome of Patients With Non–Small-Cell Lung Cancer Who Harbor EML4-ALK

(2009) Alice T. Shaw et al.   JOURNAL OF CLINICAL ONCOLOGY

Epidermal Growth Factor Receptor Mutations in Plasma DNA Samples Predict Tumor Response in Chinese Patients With Stages IIIB to IV Non–Small-Cell Lung Cancer

(2009) Hua Bai et al.   JOURNAL OF CLINICAL ONCOLOGY

Gefitinib or Carboplatin–Paclitaxel in Pulmonary Adenocarcinoma

(2009) Tony S. Mok et al.   NEW ENGLAND JOURNAL OF MEDICINE

MiR-21 is an EGFR-regulated anti-apoptotic factor in lung cancer in never-smokers

(2009) M. Seike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)

(2008) E.A. Eisenhauer et al.   EUROPEAN JOURNAL OF CANCER