Exploring the Role of Chirality in Nucleic Acid Recognition

Correction: Anti-Inflammatory Thalidomide Improves Islet Grafts Survival and Functions in a Xenogenic Environment

(2014) Chunguang Chen et al.   PLoS One

microRNAs: Master Regulators as Potential Therapeutics in Cancer

(2011) Michela Garofalo et al.   Annual Review of Pharmacology and Toxicology

Synthesis and Properties of the Simplified Nucleic Acid Glycol Nucleic Acid

(2010) Eric Meggers et al.   ACCOUNTS OF CHEMICAL RESEARCH

The Crystal Structure of D-Ribose-At Last!

(2010) Dubravka Šišak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

On the Origin of Primitive Cells: From Nutrient Intake to Elongation of Encapsulated Nucleotides

(2010) Uwe J. Meierhenrich et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Efficient asymmetric organocatalytic formation of erythrose and threose under aqueous conditions

(2010) Laurence Burroughs et al.   CHEMICAL COMMUNICATIONS

From Anionic to Cationicα-Anomeric Oligodeoxynucleotides

(2010) François Morvan et al.   CHEMISTRY & BIODIVERSITY

The Resurgence of Acyclic Nucleic Acids

(2010) Su Zhang et al.   CHEMISTRY & BIODIVERSITY

Nucleic Acids with a Six-Membered ‘Carbohydrate’ Mimic in the Backbone

(2010) Piet Herdewijn   CHEMISTRY & BIODIVERSITY

Oligonucleotides with Sugars Other Than Ribo- and 2′-Deoxyribofuranose in the Backbone: the Solution Structures Determined by NMR in the Context of the ‘Etiology of Nucleic Acids’ Project of Albert Eschenmoser

(2010) Marc-Olivier Ebert et al.   CHEMISTRY & BIODIVERSITY

Crystallographic Studies of Chemically Modified Nucleic Acids: A Backward Glance

(2010) Martin Egli et al.   CHEMISTRY & BIODIVERSITY

Locked Nucleic Acids: Promising Nucleic Acid Analogs for Therapeutic Applications

(2010) Rakesh N. Veedu et al.   CHEMISTRY & BIODIVERSITY

Peptide Nucleic Acids (PNA) in Chemical Biology and Drug Discovery

(2010) Peter E. Nielsen   CHEMISTRY & BIODIVERSITY

Naturstoff-Strukturen hinterfragen

(2010) Albert Eschenmoser   HELVETICA CHIMICA ACTA

Bridged Nucleic Acids: Development, Synthesis and Properties

(2010) Satoshi Obika et al.   HETEROCYCLES

Towardl-Homo-DNA: Stereoselective de Novo Synthesis of β-l-erythro-Hexopyranosyl Nucleosides

(2010) Daniele D’Alonzo et al.   JOURNAL OF ORGANIC CHEMISTRY

Free-Radical Ring Closure to Conformationally Locked α-l-Carba-LNAs and Synthesis of Their Oligos: Nuclease Stability, Target RNA Specificity, and Elicitation of RNase H

(2010) Qing Li et al.   JOURNAL OF ORGANIC CHEMISTRY

Unexpectedly Stable Artificial Duplex from Flexible Acyclic Threoninol

(2010) Hiroyuki Asanuma et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Aptamers as therapeutics

(2010) Anthony D. Keefe et al.   NATURE REVIEWS DRUG DISCOVERY

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Invader LNA: Efficient targeting of short double stranded DNA

(2010) Sujay P. Sau et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Influence of Montmorillonite on Nucleotide Oligomerization Reactions: A Molecular Dynamics Study

(2010) Damien C. Mathew et al.   ORIGINS OF LIFE AND EVOLUTION OF BIOSPHERES

L-amino acids catalyze the formation of an excess of D-glyceraldehyde, and thus of other D sugars, under credible prebiotic conditions

(2010) R. Breslow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Locked nucleic acid as a novel class of therapeutic agents

(2010) Rakesh N. Veedu et al.   RNA Biology

Comment on "The Silicate-Mediated Formose Reaction: Bottom-Up Synthesis of Sugar Silicates"

(2010) H.-J. Kim et al.   SCIENCE

The Silicate-Mediated Formose Reaction: Bottom-Up Synthesis of Sugar Silicates

(2010) J. B. Lambert et al.   SCIENCE

The Organic Composition of Carbonaceous Meteorites: The Evolutionary Story Ahead of Biochemistry

(2010) S. Pizzarello et al.   Cold Spring Harbor Perspectives in Biology

The Origins of Cellular Life

(2010) J. P. Schrum et al.   Cold Spring Harbor Perspectives in Biology

Ribonucleotides

(2010) J. D. Sutherland   Cold Spring Harbor Perspectives in Biology

The Origin of Biological Homochirality

(2010) D. G. Blackmond   Cold Spring Harbor Perspectives in Biology

Insight into the High Duplex Stability of the Simplified Nucleic Acid GNA

(2009) Mark K. Schlegel et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

RNA Interference: From Basic Research to Therapeutic Applications

(2009) Jens Kurreck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

FRET-based kinetic analysis of highly reactive heterochiral DNA toward EcoRI endonuclease

(2009) Hidehito Urata et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Parallel RNA-strand recognition by 2′-amino-β-l-LNA

(2009) T. Santhosh Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Non-B DNA structure-induced genetic instability and evolution

(2009) Junhua Zhao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Atomic resolution duplex structure of the simplified nucleic acidGNA

(2009) Mark K. Schlegel et al.   CHEMICAL COMMUNICATIONS

Toward Safe Genetically Modified Organisms through the Chemical Diversification of Nucleic Acids

(2009) Piet Herdewijn et al.   CHEMISTRY & BIODIVERSITY

Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic Polymers

(2009) Yevgeny Brudno et al.   CHEMISTRY & BIOLOGY

Synthesis and Base Pairing Properties of 1′,5′-Anhydro-L-Hexitol Nucleic Acids (L-HNA)

(2009) Daniele D'Alonzo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Non-natural nucleic acids for synthetic biology

(2009) Daniel H Appella   CURRENT OPINION IN CHEMICAL BIOLOGY

Recent Advances in Monosaccharide Synthesis: A Journey into L-Hexose World

(2009) Daniele D'Alonzo et al.   CURRENT ORGANIC CHEMISTRY

Exploring Chemical Space with Aptamers

(2009) Michael Famulok   JOURNAL OF MEDICINAL CHEMISTRY

N2′→P3′ Phosphoramidate Glycerol Nucleic Acid as a Potential Alternative Genetic System

(2009) Jesse J. Chen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Helical Structure of Xylose-DNA

(2009) Amutha Ramaswamy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mirror image phage display—a method to generate d-peptide ligands for use in diagnostic or therapeutical applications

(2009) Susanne Aileen Funke et al.   Molecular BioSystems

Darwinian chemistry: towards the synthesis of a simple cell

(2009) David Loakes et al.   Molecular BioSystems

Synthesis of activated pyrimidine ribonucleotides in prebiotically plausible conditions

(2009) Matthew W. Powner et al.   NATURE

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Late Onset of Ccl2 Blockade with the Spiegelmer mNOX-E36–3′PEG Prevents Glomerulosclerosis and Improves Glomerular Filtration Rate in db/db Mice

(2008) Volha Ninichuk et al.   AMERICAN JOURNAL OF PATHOLOGY

An86Y-Labeled Mirror-Image Oligonucleotide: Influence of Y-DOTA Isomers on the Biodistribution in Rats†

(2008) Joern Schlesinger et al.   BIOCONJUGATE CHEMISTRY

Triplex Formation by Pyrene-Labelled Probes for Nucleic Acid Detection in Fluorescence Assays

(2008) Ineke Van Daele et al.   CHEMBIOCHEM

Genotyping by allele-specific l-DNA-tagged PCR

(2008) G HAYASHI et al.   JOURNAL OF BIOTECHNOLOGY

Functionalized 2′-Amino-α-L-LNA: Directed Positioning of Intercalators for DNA Targeting

(2008) T. Santhosh Kumar et al.   JOURNAL OF ORGANIC CHEMISTRY

Ccl2/Mcp-1 blockade reduces glomerular and interstitial macrophages but does not ameliorate renal pathology incollagen4A3-deficient mice with autosomal recessive Alport nephropathy

(2008) Sebastian Clauss et al.   JOURNAL OF PATHOLOGY

Anti-Ccl2 Spiegelmer Permits 75% Dose Reduction of Cyclophosphamide to Control Diffuse Proliferative Lupus Nephritis and Pneumonitis in MRL-Fas(lpr) Mice

(2008) O. Kulkarni et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The Structure of a TNA−TNA Complex in Solution: NMR Study of the Octamer Duplex Derived from α-(l)-Threofuranosyl-(3′-2′)-CGAATTCG

(2008) Marc-Olivier Ebert et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Structure of the Fully Modified Left-Handed Cyclohexene Nucleic Acid Sequence GTGTACAC

(2008) Koen Robeyns et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mirror Image DNA Nanostructures for Chiral Supramolecular Assemblies

(2008) Chenxiang Lin et al.   NANO LETTERS

Template-directed synthesis of a genetic polymer in a model protocell

(2008) Sheref S. Mansy et al.   NATURE

De novo approach to l-anhydrohexitol nucleosides as building blocks for the synthesis of l-hexitol nucleic acids (l-HNA)

(2008) Daniele D’Alonzo et al.   TETRAHEDRON LETTERS

Cell penetrating peptide conjugates of steric block oligonucleotides

(2007) Bernard Lebleu et al.   ADVANCED DRUG DELIVERY REVIEWS

A Pre-RNA Candidate Revisited:  Both Enantiomers of Flexible Nucleoside Triphosphates are DNA Polymerase Substrates

(2007) Benjamin D. Heuberger et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibition of stimulated meningeal blood flow by a calcitonin gene-related peptide binding mirror-image RNA oligonucleotide

(2006) Thomas Denekas et al.   BRITISH JOURNAL OF PHARMACOLOGY