Differences between amyloid-β aggregation in solution and on the membrane: insights into elucidation of the mechanistic details of Alzheimer's disease

2D 1H/1H RFDR and NOESY NMR Experiments on a Membrane-Bound Antimicrobial Peptide Under Magic Angle Spinning

(2013) Ayyalusamy Ramamoorthy et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Alzheimer's disease: which type of amyloid-preventing drug agents to employ?

(2013) Hyunbum Jang et al.   PHYSICAL CHEMISTRY CHEMICAL PHYSICS

On the subject of rigor in the study of amyloid β-protein assembly

(2013) David B Teplow   Alzheimers Research & Therapy

Probing Structural Features of Alzheimer’s Amyloid-β Pores in Bilayers Using Site-Specific Amino Acid Substitutions

(2012) Ricardo Capone et al.   BIOCHEMISTRY

Phosphatidylethanolamine Enhances Amyloid Fiber-Dependent Membrane Fragmentation

(2012) Michele F. M. Sciacca et al.   BIOCHEMISTRY

Two-Step Mechanism of Membrane Disruption by Aβ through Membrane Fragmentation and Pore Formation

(2012) Michele F.M. Sciacca et al.   BIOPHYSICAL JOURNAL

Conformational Differences between Two Amyloid β Oligomers of Similar Size and Dissimilar Toxicity

(2012) Ali Reza A. Ladiwala et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Zn2+-Aβ40 Complexes Form Metastable Quasi-spherical Oligomers That Are Cytotoxic to Cultured Hippocampal Neurons

(2012) Inna Solomonov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

All-d-Enantiomer of β-Amyloid Peptide Forms Ion Channels in Lipid Bilayers

(2012) Ricardo Capone et al.   Journal of Chemical Theory and Computation

The Polyphenol EGCG Inhibits Amyloid Formation Less Efficiently at Phospholipid Interfaces than in Bulk Solution

(2012) Maarten F. M. Engel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

The toxic Aβ oligomer and Alzheimer's disease: an emperor in need of clothes

(2012) Iryna Benilova et al.   NATURE NEUROSCIENCE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Multivariate Analyses of Amyloid-Beta Oligomer Populations Indicate a Connection between Pore Formation and Cytotoxicity

(2012) Panchika Prangkio et al.   PLoS One

Membrane Disruption and Early Events in the Aggregation of the Diabetes Related Peptide IAPP from a Molecular Perspective

(2011) Jeffrey R. Brender et al.   ACCOUNTS OF CHEMICAL RESEARCH

A partially folded structure of amyloid-beta(1–40) in an aqueous environment

(2011) Subramanian Vivekanandan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mechanism of Amyloid β-Protein Aggregation Mediated by GM1 Ganglioside Clusters

(2011) Keisuke Ikeda et al.   BIOCHEMISTRY

Biphasic Effects of Insulin on Islet Amyloid Polypeptide Membrane Disruption

(2011) Jeffrey R. Brender et al.   BIOPHYSICAL JOURNAL

Misfolded proteins in Alzheimer's disease and type II diabetes

(2011) Alaina S. DeToma et al.   CHEMICAL SOCIETY REVIEWS

Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems

(2010) Sara M. Butterfield et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Aβ polymerization through interaction with membrane gangliosides

(2010) Katsumi Matsuzaki et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Transformation of amyloid β(1–40) oligomers into fibrils is characterized by a major change in secondary structure

(2010) Rabia Sarroukh et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

NMR characterization of the interactions between lyso-GM1 aqueous micelles and amyloid β

(2010) Maho Yagi-Utsumi et al.   FEBS LETTERS

Aβ42 Neurotoxicity Is Mediated by Ongoing Nucleated Polymerization Process Rather than by Discrete Aβ42 Species

(2010) Asad Jan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers

(2010) Sarah D. Cady et al.   NATURE

Structural conversion of neurotoxic amyloid-β1–42 oligomers to fibrils

(2010) Mahiuddin Ahmed et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Antiparallel β-sheet: a signature structure of the oligomeric amyloid β-peptide

(2009) Emilie Cerf et al.   BIOCHEMICAL JOURNAL

Structural Characterization of a Soluble Amyloid β-Peptide Oligomer

(2009) Liping Yu et al.   BIOCHEMISTRY

Structure-neurotoxicity relationships of amyloid  -protein oligomers

(2009) K. Ono et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Small molecule blockers of the Alzheimer A  calcium channel potently protect neurons from A  cytotoxicity

(2009) J. C. Diaz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Up-and-down topological mode of amyloid β-peptide lying on hydrophilic/hydrophobic interface of ganglioside clusters

(2008) Maho Utsumi et al.   GLYCOCONJUGATE JOURNAL

Annular Protofibrils Are a Structurally and Functionally Distinct Type of Amyloid Oligomer

(2008) Rakez Kayed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

New structures help the modeling of toxic amyloidß ion channels

(2008) Hyunbum Jang et al.   TRENDS IN BIOCHEMICAL SCIENCES