Anthropogenic reaction parameters – the missing link between chemical intuition and the available chemical space

Novel Process Windows for Enabling, Accelerating, and Uplifting Flow Chemistry

(2013) Volker Hessel et al.   ChemSusChem

A Forensic Analysis of Drug Targets From 2000 Through 2012

(2013) B Munos   CLINICAL PHARMACOLOGY & THERAPEUTICS

Fragment-based hit identification: thinking in 3D

(2013) Andrew D. Morley et al.   DRUG DISCOVERY TODAY

Exploring Chemical Space for Drug Discovery Using the Chemical Universe Database

(2012) Jean-Louis Reymond et al.   ACS Chemical Neuroscience

ChemBioServer: a web-based pipeline for filtering, clustering and visualization of chemical compounds used in drug discovery

(2012) E. Athanasiadis et al.   BIOINFORMATICS

Enumeration of 166 Billion Organic Small Molecules in the Chemical Universe Database GDB-17

(2012) Lars Ruddigkeit et al.   Journal of Chemical Information and Modeling

Continuous Flow Synthesis. A Pharma Perspective

(2012) Laia Malet-Sanz et al.   JOURNAL OF MEDICINAL CHEMISTRY

Chemical intuition or chemical institution?

(2012) Bruce C. Gibb   Nature Chemistry

Highly Parallel Translation of DNA Sequences into Small Molecules

(2012) Rebecca M. Weisinger et al.   PLoS One

Inside the Mind of a Medicinal Chemist: The Role of Human Bias in Compound Prioritization during Drug Discovery

(2012) Peter S. Kutchukian et al.   PLoS One

Palladium-Catalyzed Direct Arylation of Heteroaromatic Compounds: Improved Conditions Utilizing Controlled Microwave Heating

(2011) Mostafa Baghbanzadeh et al.   JOURNAL OF ORGANIC CHEMISTRY

Too many roads not taken

(2011) Aled M. Edwards et al.   NATURE

Design of frustrated Lewis pair catalysts for metal-free and selective hydrogenation

(2011) Tibor Soós   PURE AND APPLIED CHEMISTRY

Discovery of an  -Amino C-H Arylation Reaction Using the Strategy of Accelerated Serendipity

(2011) A. McNally et al.   SCIENCE

Synthesis of 5-Substituted 1H-Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High-Temperature Microreactor Approach

(2010) Bernhard Gutmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Homogeneous Gold Catalysis Beyond Assumptions and Proposals-Characterized Intermediates

(2010) A. Stephen K. Hashmi   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding the Scope of Metal-Free Catalytic Hydrogenation through Frustrated Lewis Pair Design

(2010) Gábor Erős et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel process windows – Concept, proposition and evaluation methodology, and intensified superheated processing

(2010) Volker Hessel et al.   CHEMICAL ENGINEERING SCIENCE

The (un)targeted cancer kinome

(2010) Oleg Fedorov et al.   Nature Chemical Biology

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

The rate of growth in scientific publication and the decline in coverage provided by Science Citation Index

(2010) Peder Olesen Larsen et al.   SCIENTOMETRICS

Frustrated Lewis Pairs: Metal-free Hydrogen Activation and More

(2009) Douglas W. Stephan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microwave Chemistry in Silicon Carbide Reaction Vials: Separating Thermal from Nonthermal Effects

(2009) David Obermayer et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Heuristic thinking makes a chemist smart

(2009) Nicole Graulich et al.   CHEMICAL SOCIETY REVIEWS

Drug and Drug Candidate Building Block Analysis

(2009) Junmei Wang et al.   Journal of Chemical Information and Modeling

Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success

(2009) Frank Lovering et al.   JOURNAL OF MEDICINAL CHEMISTRY

970 Million Druglike Small Molecules for Virtual Screening in the Chemical Universe Database GDB-13

(2009) Lorenz C. Blum et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Translating High-Temperature Microwave Chemistry to Scalable Continuous Flow Processes

(2009) Markus Damm et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Gold-Catalyzed Organic Transformations

(2008) Zigang Li et al.   CHEMICAL REVIEWS

Alternative Synthetic Methods through New Developments in Catalysis by Gold

(2008) Antonio Arcadi   CHEMICAL REVIEWS

The Changing Face of Organic Synthesis

(2008) Steven V. Ley et al.   CHIMIA

Structural Diversity of Organic Chemistry. A Scaffold Analysis of the CAS Registry

(2008) Alan H. Lipkus et al.   JOURNAL OF ORGANIC CHEMISTRY

Tuning of Chemo- and Regioselectivities in Multicomponent Condensations of 5-Aminopyrazoles, Dimedone, and Aldehydes

(2008) Valentin A. Chebanov et al.   JOURNAL OF ORGANIC CHEMISTRY

Kinase requirements in human cells: I. Comparing kinase requirements across various cell types

(2008) D. A. Grueneberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA