A general overview of the organocatalytic intramolecular aza-Michael reaction

Enantioselective Synthesis of Azaflavanones Using Organocatalytic 6-endoAza-Michael Addition

(2014) Shuanghua Cheng et al.   ADVANCED SYNTHESIS & CATALYSIS

A gram-scale route to phlegmarine alkaloids: rapid total synthesis of (−)-cermizine B

(2014) Ben Bradshaw et al.   CHEMICAL COMMUNICATIONS

Ruthenium(II)/Chiral Brønsted Acid Co-Catalyzed Enantioselective Four-Component Reaction/Cascade Aza-Michael Addition for Efficient Construction of 1,3,4-Tetrasubstituted Tetrahydroisoquinolines

(2014) Jun Jiang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of 1,3-Oxazolidines via Intramolecular Aza-Michael Addition by Bifunctional Organocatalysts

(2013) Yukihiro Fukata et al.   CHEMISTRY LETTERS

Organocatalytic Asymmetric Synthesis of Tetracyclic Pyridocarbazole Derivatives by Using a Diels-Alder/aza-Michael/Aldol Condensation Domino Reaction

(2013) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthetic and DFT Studies Towards a Unified Approach to Phlegmarine Alkaloids: Aza-Michael Intramolecular Processes Leading to 5-Oxodecahydroquinolines

(2013) Ben Bradshaw et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Approach to Quinolizidines: Total Synthesis of Cermizine D and Formal Syntheses of Senepodine G and Cermizine C

(2013) Nagarathanam Veerasamy et al.   JOURNAL OF ORGANIC CHEMISTRY

A Mechanistic Rationale for the 9-Amino(9-deoxy)epi Cinchona Alkaloids Catalyzed Asymmetric Reactions via Iminium Ion Activation of Enones

(2013) Antonio Moran et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Recent contributions from the asymmetric aza-Michael reaction to alkaloids total synthesis

(2013) Zacharias Amara et al.   NATURAL PRODUCT REPORTS

Asymmetric Indoline Synthesis via Intramolecular Aza-Michael Addition Mediated by Bifunctional Organocatalysts

(2013) Ryota Miyaji et al.   ORGANIC LETTERS

Organocatalyzed Asymmetric Synthesis of Morphans

(2013) Ben Bradshaw et al.   ORGANIC LETTERS

Enantioselective [4 + 2] Cycloaddition of Cyclic N-Sulfimines and Acyclic Enones or Ynones: A Concise Route to Sulfamidate-Fused 2,6-Disubstituted Piperidin-4-ones

(2013) Yong Liu et al.   ORGANIC LETTERS

A Highly Diastereoselective and Enantioselective Synthesis of Polysubstituted Pyrrolidines via an Organocatalytic Dynamic Kinetic Resolution Cascade

(2013) Tao Cheng et al.   ORGANIC LETTERS

Recent Developments in Asymmetric Organocatalytic Domino Reactions

(2012) Hélène Pellissier   ADVANCED SYNTHESIS & CATALYSIS

Cinchona-based Primary Amine Catalysis in the Asymmetric Functionalization of Carbonyl Compounds

(2012) Paolo Melchiorre   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Advances and Applications in Organocatalytic Asymmetric aza-Michael Addition

(2012) Jun Wang et al.   ChemCatChem

Kinetics and mechanism of organocatalytic aza-Michael additions: direct observation of enamine intermediates

(2012) Sami Lakhdar et al.   CHEMICAL COMMUNICATIONS

Quadruple Domino Organocatalysis: An Asymmetric Aza-Michael/Michael/Michael/Aldol Reaction Sequence Leading to Tetracyclic Indole Structures with Six Stereocenters

(2012) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Synthesis of 2,3-Dihydroquinolin-4-one Derivatives Catalyzed by a Chiral Bisguanidium Salt

(2012) Xiao Xiao et al.   CHEMISTRY-A EUROPEAN JOURNAL

Organocatalytic Enantioselective aza-Michael Reactions

(2012) Efraim Reyes et al.   CURRENT ORGANIC CHEMISTRY

Tandem Sequence of Phenol Oxidation and Intramolecular Addition as a Method in Building Heterocycles

(2012) Maxim O. Ratnikov et al.   JOURNAL OF ORGANIC CHEMISTRY

Expedient Enantioselective Synthesis of Cermizine D

(2012) Nagarathanam Veerasamy et al.   ORGANIC LETTERS

cis-Decahydroquinolines via Asymmetric Organocatalysis: Application to the Total Synthesis of Lycoposerramine Z

(2012) Ben Bradshaw et al.   ORGANIC LETTERS

Enantioselective synthesis of 2-substituted pyrrolidinesvia domino cross metathesis/intramolecular aza-Michael addition

(2012) Hanbin Liu et al.   RSC Advances

Asymmetric Organocatalytic Intramolecular Aza-Michael Addition of Enone Carbamates: Catalytic Enantioselective Access to Functionalized 2-Substituted Piperidines

(2011) Jian-Dong Liu et al.   ADVANCED SYNTHESIS & CATALYSIS

A Simple Recipe for Sophisticated Cocktails: Organocatalytic One-Pot Reactions-Concept, Nomenclature, and Future Perspectives

(2011) Łukasz Albrecht et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Microwave-Assisted Organocatalytic Enantioselective Intramolecular aza-Michael Reaction with α,β-Unsaturated Ketones

(2011) Santos Fustero  et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Organocatalytic α-Fluorination of Cyclic Ketones

(2011) Piotr Kwiatkowski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective Synthesis of 2,6-cis- and 2,6-trans-Piperidines through Organocatalytic Aza-Michael Reactions: A Facile Synthesis of (+)-Myrtine and (−)-Epimyrtine

(2011) Yongcheng Ying et al.   ORGANIC LETTERS

Organocatalytic enantioselective synthesis of quinolizidine alkaloids (+)-myrtine, (−)-lupinine, and (+)-epiepiquinamide

(2011) Santos Fustero et al.   TETRAHEDRON

Desymmetrization of cyclohexadienones via cinchonine derived thiourea-catalyzed enantioselective aza-Michael reaction and total synthesis of (-)-Mesembrine

(2011) Qing Gu et al.   Chemical Science

Asymmetric Synthesis of Polyfunctionalized Pyrrolidines via a Thiourea Catalyzed Domino Mannich/Aza-Michael Reaction

(2010) Dieter Enders et al.   ADVANCED SYNTHESIS & CATALYSIS

Enantioselective Intramolecular Aza-Michael Additions of Indoles Catalyzed by Chiral Phosphoric Acids

(2010) Quan Cai et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Synthesis of Isoindolines: An Organocatalyzed Domino Process Based On the aza-Morita-Baylis-Hillman Reaction

(2010) Shinobu Takizawa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Phase-Transfer-Catalyzed Intramolecular N-Alkylation of Indoles and Pyrroles: A Combined Experimental and Theoretical Investigation

(2010) Marco Bandini et al.   CHEMISTRY-A EUROPEAN JOURNAL

Discovery of the Michael Reaction

(2010) Takashi Tokoroyama   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Formal Syntheses of Dihydrocorynantheine and Isorhynchophylline via Proline Catalyzed Mannich-Michael Reaction

(2010) Takashi Itoh et al.   HETEROCYCLES

Enantioselective Synthesis of 2-Aryl-2,3-dihydro-4-quinolones by Chiral Brønsted Acid Catalyzed Intramolecular Aza-Michael Addition Reaction

(2010) Shu-Li You et al.   HETEROCYCLES

Organocatalytic cascade reactions as a new tool in total synthesis

(2010) Christoph Grondal et al.   Nature Chemistry

Asymmetric Synthesis of 2-Aryl-2,3-dihydro-4-quinolones via Bifunctional Thiourea-Mediated Intramolecular Cyclization

(2010) Xiaoqian Liu et al.   ORGANIC LETTERS

Organocatalytic Asymmetric Aza-Michael Additions

(2009) Dieter Enders et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Construction of Nitrogen-Containing [2.2.2] Bicyclic Scaffolds UsingN-(p-Dodecylphenylsulfonyl)-2-pyrrolidinecarboxamide

(2009) Hua Yang et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Phase-Transfer-Catalyzed Intramolecular Aza-Michael Reaction: Effective Route to Pyrazino-Indole Compounds

(2008) Marco Bandini et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Aza-Michael Reactions of α,β-Unsaturated Ketones with Bifunctional Organic Catalysts

(2008) Xiaojie Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric α-Aminoxylation/Aza-Michael Reactions for the Synthesis of Functionalized Tetrahydro-1,2-oxazines

(2008) Min Lu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Brønsted Acid Catalyzed Isoindoline Synthesis: Enhancement of Enantiomeric Ratio by Stereoablative Kinetic Resolution

(2008) Dieter Enders et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Asymmetric Aziridination of Enones

(2008) Fabio Pesciaioli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Approach to Benzofused Nitrogen-Containing Heterocycles: Enantioselective Total Synthesis of (+)-Angustureine

(2008) Santos Fustero et al.   CHEMISTRY-A EUROPEAN JOURNAL

Improved Protocol for Asymmetric, Intramolecular Heteroatom Michael Addition Using Organocatalysis: Enantioselective Syntheses of Homoproline, Pelletierine, and Homopipecolic Acid

(2008) Erik C. Carlson et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective Formal Synthesis of (+)-Dihydrocorynantheine and (−)-Dihydrocorynantheol†

(2008) Mercedes Amat et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly Enantioselective Aldol Reactions Catalyzed by a Recyclable Fluorous (S) Pyrrolidine Sulfonamide on Water

(2008) Liansuo Zu et al.   ORGANIC LETTERS