Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
出版年份 2010 全文链接
标题
Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy
作者
关键词
-
出版物
CHEMICAL SOCIETY REVIEWS
Volume 40, Issue 1, Pages 387-426
出版商
Royal Society of Chemistry (RSC)
发表日期
2010-08-17
DOI
10.1039/b906712b
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Responsive MRI Agents for Sensing Metabolismin Vivo
- (2009) Luis M. De Leon-Rodriguez et al. ACCOUNTS OF CHEMICAL RESEARCH
- Cellular imaging with secondary ion mass spectrometry
- (2009) John S. Fletcher ANALYST
- Mass spectrometry tools and metabolite-specific databases for molecular identification in metabolomics
- (2009) M. Brown et al. ANALYST
- Metabonomics studies of intact hepatic and renal cortical tissues from diabetic db/db mice using high-resolution magic-angle spinning 1H NMR spectroscopy
- (2009) Jingjing Xu et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Investigation of Human Blood Plasma Sample Preparation for Performing Metabolomics Using Ultrahigh Performance Liquid Chromatography/Mass Spectrometry
- (2009) Stephen J. Bruce et al. ANALYTICAL CHEMISTRY
- Variable Selection Using Iterative Reformulation of Training Set Models for Discrimination of Samples: Application to Gas Chromatography/Mass Spectrometry of Mouse Urinary Metabolites
- (2009) Kanet Wongravee et al. ANALYTICAL CHEMISTRY
- MetAlign: Interface-Driven, Versatile Metabolomics Tool for Hyphenated Full-Scan Mass Spectrometry Data Preprocessing
- (2009) Arjen Lommen ANALYTICAL CHEMISTRY
- Automated Principal Component-Based Orthogonal Signal Correction Applied to Fused Near Infrared−Mid-Infrared Spectra of French Olive Oils
- (2009) Peter de B. Harrington et al. ANALYTICAL CHEMISTRY
- Development and Performance of a Gas Chromatography−Time-of-Flight Mass Spectrometry Analysis for Large-Scale Nontargeted Metabolomic Studies of Human Serum
- (2009) Paul Begley et al. ANALYTICAL CHEMISTRY
- Development of a Robust and Repeatable UPLC−MS Method for the Long-Term Metabolomic Study of Human Serum
- (2009) Eva Zelena et al. ANALYTICAL CHEMISTRY
- FiehnLib: Mass Spectral and Retention Index Libraries for Metabolomics Based on Quadrupole and Time-of-Flight Gas Chromatography/Mass Spectrometry
- (2009) Tobias Kind et al. ANALYTICAL CHEMISTRY
- Pitfalls of supervised feature selection
- (2009) Pawel Smialowski et al. BIOINFORMATICS
- Metabolite signal identification in accurate mass metabolomics data with MZedDB, an interactive m/z annotation tool utilising predicted ionisation behaviour 'rules'
- (2009) John Draper et al. BMC BIOINFORMATICS
- Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
- (2009) Douglas B Kell BMC Medical Genomics
- Biomarkers of Dietary Energy Restriction in Women at Increased Risk of Breast Cancer
- (2009) K. R. Ong et al. Cancer Prevention Research
- A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance
- (2009) Christopher B. Newgard et al. Cell Metabolism
- Effects of Mainstream Cigarette Smoke on the Global Metabolome of Human Lung Epithelial Cells
- (2009) Suryanarayana V. Vulimiri et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Metallomics: the concept and methodology
- (2009) Sandra Mounicou et al. CHEMICAL SOCIETY REVIEWS
- Metabolomic Profiling Reveals Distinct Patterns of Myocardial Substrate Use in Humans With Coronary Artery Disease or Left Ventricular Dysfunction During Surgical Ischemia/Reperfusion
- (2009) Aslan T. Turer et al. CIRCULATION
- Biomarkers of primary and evolving damage in traumatic and ischemic brain injury: diagnosis, prognosis, probing mechanisms, and therapeutic decision making
- (2009) Patrick M Kochanek et al. Current Opinion in Critical Care
- Novel biological insights through metabolomics and 13C-flux analysis
- (2009) Nicola Zamboni et al. CURRENT OPINION IN MICROBIOLOGY
- Adaptation and failure of pancreatic cells in murine models with different degrees of metabolic syndrome
- (2009) G. Medina-Gomez et al. Disease Models & Mechanisms
- Prospects for clinical cancer metabolomics using stable isotope tracers
- (2009) Andrew N. Lane et al. EXPERIMENTAL AND MOLECULAR PATHOLOGY
- Real-time assessment of Krebs cycle metabolism using hyperpolarized 13C magnetic resonance spectroscopy
- (2009) Marie A. Schroeder et al. FASEB JOURNAL
- Measurement of dietary exposure: a challenging problem which may be overcome thanks to metabolomics?
- (2009) Gaëlle Favé et al. Genes and Nutrition
- Biomarkers in nutritional epidemiology: applications, needs and new horizons
- (2009) Mazda Jenab et al. HUMAN GENETICS
- Analytical strategies in lipidomics and applications in disease biomarker discovery
- (2009) Chunxiu Hu et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Identification of double bond position in lipids: From GC to OzID
- (2009) Todd W. Mitchell et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Enhanced modification of cardiolipin during ischemia in the aged heart
- (2009) Edward J. Lesnefsky et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Database Resources in Metabolomics: An Overview
- (2009) Eden P. Go Journal of Neuroimmune Pharmacology
- Analytical Error Reduction Using Single Point Calibration for Accurate and Precise Metabolomic Phenotyping
- (2009) Frans M. van der Kloet et al. JOURNAL OF PROTEOME RESEARCH
- Response and Recovery in the Plasma Metabolome Tracks the Acute LCMV-Induced Immune Response
- (2009) William R. Wikoff et al. JOURNAL OF PROTEOME RESEARCH
- UPLC-MS-Based Analysis of Human Plasma for Metabonomics Using Solvent Precipitation or Solid Phase Extraction
- (2009) Filippos Michopoulos et al. JOURNAL OF PROTEOME RESEARCH
- Detection of Metabolic Alterations in Non-tumor Gastrointestinal Tissue of theApcMin/+Mouse by1H MAS NMR Spectroscopy
- (2009) Alexandra Backshall et al. JOURNAL OF PROTEOME RESEARCH
- Application of Ultra Performance Liquid Chromatography−Mass Spectrometry to Profiling Rat and Dog Bile
- (2009) Robert S. Plumb et al. JOURNAL OF PROTEOME RESEARCH
- Altered regulation of metabolic pathways in human lung cancer discerned by 13C stable isotope-resolved metabolomics (SIRM)
- (2009) Teresa WM Fan et al. Molecular Cancer
- Metabolomics and its application for non-invasive embryo assessment in IVF
- (2009) L. Botros et al. MOLECULAR HUMAN REPRODUCTION
- Predicting metabolic biomarkers of human inborn errors of metabolism
- (2009) Tomer Shlomi et al. Molecular Systems Biology
- Metabolomics of the interaction between PPAR-α and age in the PPAR-α-null mouse
- (2009) Helen J Atherton et al. Molecular Systems Biology
- Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression
- (2009) Arun Sreekumar et al. NATURE
- 13C-based metabolic flux analysis
- (2009) Nicola Zamboni et al. Nature Protocols
- Understanding the human salivary metabolome
- (2009) Ienaka Takeda et al. NMR IN BIOMEDICINE
- SMPDB: The Small Molecule Pathway Database
- (2009) Alex Frolkis et al. NUCLEIC ACIDS RESEARCH
- An introduction to liquid chromatographyâmass spectrometry instrumentation applied in plant metabolomic analyses
- (2009) J. William Allwood et al. PHYTOCHEMICAL ANALYSIS
- Changes in the Metabolic Footprint of Placental Explant-Conditioned Culture Medium Identifies Metabolic Disturbances Related to Hypoxia and Pre-Eclampsia
- (2009) W.B. Dunn et al. PLACENTA
- Natural Product Analysis over the Last Decades
- (2009) Andrew Marston et al. PLANTA MEDICA
- Acid-base-driven matrix-assisted mass spectrometry for targeted metabolomics
- (2009) R. Shroff et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Bioinformatic methods in NMR-based metabolic profiling
- (2009) Timothy M.D. Ebbels et al. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
- From lipid analysis towards lipidomics, a new challenge for the analytical chemistry of the 21st century. Part I: Modern lipid analysis
- (2009) Alegría Carrasco-Pancorbo et al. TRAC-TRENDS IN ANALYTICAL CHEMISTRY
- Bridging the gap between systems biology and medicine
- (2009) Gilles Clermont et al. Genome Medicine
- Coordinated Concentration Changes of Transcripts and Metabolites in Saccharomyces cerevisiae
- (2009) Patrick H. Bradley et al. PLoS Computational Biology
- Evaluation of the Potential Excess of Statistically Significant Findings in Published Genetic Association Studies: Application to Alzheimer's Disease
- (2008) Fotini K. Kavvoura et al. AMERICAN JOURNAL OF EPIDEMIOLOGY
- Spectral relative standard deviation: a practical benchmark in metabolomics
- (2008) Helen M. Parsons et al. ANALYST
- GC-MS with ethyl chloroformate derivatization for comprehensive analysis of metabolites in serum and its application to human uremia
- (2008) Xiumei Tao et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Capillary Electrophoresis-Fourier Transform Ion Cyclotron Resonance Mass Spectrometry for the Identification of Cationic Metabolites via a pH-Mediated Stacking-Transient Isotachophoretic Method
- (2008) Edward E. K. Baidoo et al. ANALYTICAL CHEMISTRY
- Global Metabolic Profiling ofEscherichia coliCultures: an Evaluation of Methods for Quenching and Extraction of Intracellular Metabolites
- (2008) Catherine L. Winder et al. ANALYTICAL CHEMISTRY
- Self-Consistent Metabolic Mixture Analysis by Heteronuclear NMR. Application to a Human Cancer Cell Line
- (2008) Fengli Zhang et al. ANALYTICAL CHEMISTRY
- Effective Quenching Processes for Physiologically Valid Metabolite Profiling of Suspension Cultured Mammalian Cells
- (2008) Christopher A. Sellick et al. ANALYTICAL CHEMISTRY
- Live Single-cell Metabolomics of Tryptophan and Histidine Metabolites in a Rat Basophil Leukemia Cell
- (2008) Hajime MIZUNO et al. ANALYTICAL SCIENCES
- Genetic algorithms for simultaneous variable and sample selection in metabonomics
- (2008) Rachel Cavill et al. BIOINFORMATICS
- Probabilistic assignment of formulas to mass peaks in metabolomics experiments
- (2008) Simon Rogers et al. BIOINFORMATICS
- Towards de novo identification of metabolites by analyzing tandem mass spectra
- (2008) S. Bocker et al. BIOINFORMATICS
- MetaFIND: A feature analysis tool for metabolomics data
- (2008) Kenneth Bryan et al. BMC BIOINFORMATICS
- MetaboMiner – semi-automated identification of metabolites from 2D NMR spectra of complex biofluids
- (2008) Jianguo Xia et al. BMC BIOINFORMATICS
- The genome-scale metabolic model iIN800 of Saccharomyces cerevisiae and its validation: a scaffold to query lipid metabolism
- (2008) Intawat Nookaew et al. BMC Systems Biology
- Metabolomic profiling to develop blood biomarkers for Parkinson's disease
- (2008) M. Bogdanov et al. BRAIN
- Cardiolipin, the heart of mitochondrial metabolism
- (2008) R. H. Houtkooper et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- NMR-Based Metabolic Profiling and Metabonomic Approaches to Problems in Molecular Toxicology
- (2008) Muireann Coen et al. CHEMICAL RESEARCH IN TOXICOLOGY
- Bioinformatics and computational approaches applicable to lipidomics
- (2008) Matej Orešič EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY
- Riboswitch RNAs: using RNA to sense cellular metabolism
- (2008) T. M. Henkin GENES & DEVELOPMENT
- A GC-TOF-MS study of the stability of serum and urine metabolomes during the UK Biobank sample collection and preparation protocols
- (2008) W. B Dunn et al. INTERNATIONAL JOURNAL OF EPIDEMIOLOGY
- BioMagResBank (BMRB) as a partner in the Worldwide Protein Data Bank (wwPDB): new policies affecting biomolecular NMR depositions
- (2008) John L. Markley et al. JOURNAL OF BIOMOLECULAR NMR
- New insights into cardiovascular and lipid metabolomics
- (2008) Alfonso Giovane et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- Novel, fully automatic hydrophilic interaction/reversed-phase column-switching high-performance liquid chromatographic system for the complementary analysis of polar and apolar compounds in complex samples
- (2008) Yuan Wang et al. JOURNAL OF CHROMATOGRAPHY A
- High temperature-ultra performance liquid chromatography–mass spectrometry for the metabonomic analysis of Zucker rat urine
- (2008) Helen G. Gika et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Global metabolic profiling analysis on human urine by UPLC–TOFMS: Issues and method validation in nutritional metabolomics
- (2008) Philippe A. Guy et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- A matter of fat: An introduction to lipidomic profiling methods
- (2008) Lee D. Roberts et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Analytical strategies for LC–MS-based targeted metabolomics
- (2008) Wenyun Lu et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Cross-platform Q-TOF validation of global exo-metabolomic analysis: Application to human glioblastoma cells treated with the standard PI 3-Kinase inhibitor LY294002☆
- (2008) R. Pandher et al. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES
- Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury
- (2008) Gregory D. Lewis et al. JOURNAL OF CLINICAL INVESTIGATION
- Multiparametric analysis of amino acids and organic acids in rat brain tissues using GC/MS
- (2008) Jingchao Lin et al. JOURNAL OF SEPARATION SCIENCE
- Hydrophilic interaction and reversed-phase ultra-performance liquid chromatography TOF-MS for metabonomic analysis of Zucker rat urine
- (2008) Helen G. Gika et al. JOURNAL OF SEPARATION SCIENCE
- Assessment of PLSDA cross validation
- (2008) Johan A. Westerhuis et al. Metabolomics
- Metabolite profiling of human colon carcinoma – deregulation of TCA cycle and amino acid turnover
- (2008) Carsten Denkert et al. Molecular Cancer
- Systems biology: Metabonomics
- (2008) Jeremy K. Nicholson et al. NATURE
- Metabolite identification via the Madison Metabolomics Consortium Database
- (2008) Qiu Cui et al. NATURE BIOTECHNOLOGY
- Systems-level metabolic flux profiling identifies fatty acid synthesis as a target for antiviral therapy
- (2008) Joshua Munger et al. NATURE BIOTECHNOLOGY
- A consensus yeast metabolic network reconstruction obtained from a community approach to systems biology
- (2008) Markus J Herrgård et al. NATURE BIOTECHNOLOGY
- Explanatory signal interpretation and metabolite identification strategies for nominal mass FIE-MS metabolite fingerprints
- (2008) David P Overy et al. Nature Protocols
- Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
- (2008) Deborah M. Muoio et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Metabolite profiling of fecal water extracts from human colorectal cancer
- (2008) Daniel Monleón et al. NMR IN BIOMEDICINE
- HMDB: a knowledgebase for the human metabolome
- (2008) D. S. Wishart et al. NUCLEIC ACIDS RESEARCH
- Analysis of the adult human plasma metabolome
- (2008) Kay A Lawton et al. PHARMACOGENOMICS
- Analysis of the hibernation cycle using LC-MS-based metabolomics in ground squirrel liver
- (2008) Clark J. Nelson et al. PHYSIOLOGICAL GENOMICS
- Analysis of the Metabolic Footprint and Tissue Metabolome of Placental Villous Explants Cultured at Different Oxygen Tensions Reveals Novel Redox Biomarkers
- (2008) A.E.P. Heazell et al. PLACENTA
- Characterization of the ABA-regulated global responses to dehydration in Arabidopsis by metabolomics
- (2008) Kaoru Urano et al. PLANT JOURNAL
- A general framework for multiple testing dependence
- (2008) J. T. Leek et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Higher criticism thresholding: Optimal feature selection when useful features are rare and weak
- (2008) D. Donoho et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-resolution magic angle spinning (HR MAS) MR spectroscopy in metabolic characterization of human cancer
- (2008) Beathe Sitter et al. PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY
- Cluster TOF-SIMS imaging: A new light for in situ metabolomics?
- (2008) Sebastian Mas et al. PROTEOMICS
- Exploring the role of BRCA1, BRCA2 and RAD51 as biomarkers for breast cancer
- (2008) D. Ziogas et al. RADIOTHERAPY AND ONCOLOGY
- Metabolomic profiling using Orbitrap Fourier transform mass spectrometry with hydrophilic interaction chromatography: a method with wide applicability to analysis of biomolecules
- (2008) A. Kamleh et al. RAPID COMMUNICATIONS IN MASS SPECTROMETRY
- Detection and Identification of Novel Metabolomic Biomarkers in Preeclampsia
- (2008) Louise C. Kenny et al. Reproductive Sciences
- Genetics Meets Metabolomics: A Genome-Wide Association Study of Metabolite Profiles in Human Serum
- (2008) Christian Gieger et al. PLoS Genetics
- Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity
- (2008) Kirsi H Pietiläinen et al. PLOS MEDICINE
- Evaluation of a protocol for metabolic profiling studies on human blood plasma by combined ultra-performance liquid chromatography/mass spectrometry: From extraction to data analysis
- (2007) Stephen J. Bruce et al. ANALYTICAL BIOCHEMISTRY
- High-throughput tissue extraction protocol for NMR- and MS-based metabolomics
- (2007) Huifeng Wu et al. ANALYTICAL BIOCHEMISTRY
- Critical evaluation of 1H NMR metabonomics of serum as a methodology for disease risk assessment and diagnostics
- (2007) Mika Ala-Korpela CLINICAL CHEMISTRY AND LABORATORY MEDICINE
- Higher mass loadability in comprehensive two-dimensional gas chromatography–mass spectrometry for improved analytical performance in metabolomics analysis
- (2007) Maud M. Koek et al. JOURNAL OF CHROMATOGRAPHY A
- Recent advancements in comprehensive two-dimensional separations with chemometrics
- (2007) Karisa M. Pierce et al. JOURNAL OF CHROMATOGRAPHY A
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation