Hybrid lipid oligonucleotide conjugates: synthesis, self-assemblies and biomedical applications

Programmable Shape-Shifting Micelles

(2010) Miao-Ping Chien et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Properties of Double-Stranded Oligonucleotides Modified with Lipophilic Substituents

(2010) Brian M. Laing et al.   BIOCONJUGATE CHEMISTRY

Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2′-deoxyuridines

(2010) Sun Min Park et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

DNA-Based Micelles: Synthesis, Micellar Properties and Size-Dependent Cell Permeability

(2010) Haipeng Liu et al.   CHEMISTRY-A EUROPEAN JOURNAL

Lipophilic siRNAs mediate efficient gene silencing in oligodendrocytes with direct CNS delivery

(2010) Qingmin Chen et al.   JOURNAL OF CONTROLLED RELEASE

Modulation of Density and Orientation of Amphiphilic DNA on Phospholipid Membranes. II. Vesicles

(2010) Martina Banchelli et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Modulation of Density and Orientation of Amphiphilic DNA Anchored to Phospholipid Membranes. I. Supported Lipid Bilayers

(2010) Filippo Gambinossi et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Cooperative Melting in Caged Dimers with Only Two DNA Duplexes

(2010) Ibrahim Eryazici et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Virus-like Particles Templated by DNA Micelles: A General Method for Loading Virus Nanocarriers

(2010) Minseok Kwak et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Lipid Domain Specific Recruitment of Lipophilic Nucleic Acids: A Key for Switchable Functionalization of Membranes

(2010) Martin Loew et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Vesicles Tethered to Microbubbles by Hybridized DNA Oligonucleotides: Flow Cytometry Analysis of This New Drug Delivery Vehicle Design

(2010) Monica M. Lozano et al.   LANGMUIR

Covalent Attachment of Lipid Vesicles to a Fluid-Supported Bilayer Allows Observation of DNA-Mediated Vesicle Interactions

(2010) Bettina van Lengerich et al.   LANGMUIR

Smart Lipids for Programmable Nanomaterials

(2010) Matthew P. Thompson et al.   NANO LETTERS

Liposome-Based Chemical Barcodes for Single Molecule DNA Detection Using Imaging Mass Spectrometry

(2010) Anders Gunnarsson et al.   NANO LETTERS

Therapeutic silencing of miR-10b inhibits metastasis in a mouse mammary tumor model

(2010) Li Ma et al.   NATURE BIOTECHNOLOGY

Targeting microRNAs in cancer: rationale, strategies and challenges

(2010) Ramiro Garzon et al.   NATURE REVIEWS DRUG DISCOVERY

Fluorocarbon oligonucleotide conjugates for nucleic acids delivery

(2010) Guilhem Godeau et al.   MedChemComm

Small silencing RNAs: State-of-the-art

(2009) Dirk Grimm   ADVANCED DRUG DELIVERY REVIEWS

Solid-Phase Synthesis of Oligonucleotide Conjugates Useful for Delivery and Targeting of Potential Nucleic Acid Therapeutics

(2009) Harri Lönnberg   BIOCONJUGATE CHEMISTRY

Lipid-anchored DNA mediates vesicle fusion as observed by lipid and content mixing

(2009) Yee-Hung M. Chan et al.   Biointerphases

DNA as Membrane-Bound Ligand-Receptor Pairs: Duplex Stability Is Tuned by Intermembrane Forces

(2009) Paul A. Beales et al.   BIOPHYSICAL JOURNAL

Partitioning of Membrane-Anchored DNA between Coexisting Lipid Phases†

(2009) Paul A. Beales et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Lipid Membranes Carrying Lipophilic Cholesterol-Based Oligonucleotides—Characterization and Application on Layer-by-Layer Coated Particles

(2009) Andreas Bunge et al.   JOURNAL OF PHYSICAL CHEMISTRY B

DNA modification of live cell surface

(2009) Grigory G. Borisenko et al.   NUCLEIC ACIDS RESEARCH

Kinetic and thermodynamic characterization of single-mismatch discrimination using single-molecule imaging

(2009) Anders Gunnarsson et al.   NUCLEIC ACIDS RESEARCH

Programmed assembly of 3-dimensional microtissues with defined cellular connectivity

(2009) Z. J. Gartner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Effects of linker sequences on vesicle fusion mediated by lipid-anchored DNA oligonucleotides

(2009) Y.-H. M. Chan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DNA aptamer-micelle as an efficient detection/delivery vehicle toward cancer cells

(2009) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Controlled Assembly of Vesicle-Based Nanocontainers on Layer-by-Layer Particles via DNA Hybridization

(2009) Martin Loew et al.   Small

Closed nanoconstructs assembled by step-by-step ss-DNA coupling assisted by phospholipid membranes

(2009) Francesca Baldelli Bombelli et al.   Soft Matter

Synthesis and silencing properties of siRNAs possessing lipophilic groups at their 3′-termini

(2008) Yoshihito Ueno et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Sensitive liposomes encoded with oligonucleotide amphiphiles: a biocompatible switch

(2008) Arnaud Gissot et al.   CHEMICAL COMMUNICATIONS

Directed aggregation and fusion of lipid vesicles induced by DNA-surfactants

(2008) Tatsuo Maruyama et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Lipid-Conjugated Oligonucleotides via “Click Chemistry” Efficiently Inhibit Hepatitis C Virus Translation

(2008) Guilhem Godeau et al.   JOURNAL OF MEDICINAL CHEMISTRY

Determinants for Membrane Fusion Induced by Cholesterol-Modified DNA Zippers

(2008) Gudrun Stengel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Phospholipid Membranes Decorated by Cholesterol-Based Oligonucleotides as Soft Hybrid Nanostructures

(2008) Martina Banchelli et al.   JOURNAL OF PHYSICAL CHEMISTRY B

“Three-Dimensional Hybridization” with Polyvalent DNA−Gold Nanoparticle Conjugates

(2008) Sarah J. Hurst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

DNA-Controlled Assembly of Soft Nanoparticles

(2008) Ulla Jakobsen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Efficient In Vivo Delivery of siRNA to the Liver by Conjugation of α-Tocopherol

(2008) Kazutaka Nishina et al.   MOLECULAR THERAPY

Direct CNS Delivery of siRNA Mediates Robust Silencing in Oligodendrocytes

(2008) William Querbes et al.   OLIGONUCLEOTIDES

Nucleoside, nucleotide and oligonucleotide based amphiphiles: a successful marriage of nucleic acids with lipids

(2008) Arnaud Gissot et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

2′-Lipid-modified oligonucleotides via a ‘Staudinger–Vilarrasa’ reaction

(2008) Hubert Chapuis et al.   TETRAHEDRON LETTERS

Single-Molecule Detection and Mismatch Discrimination of Unlabeled DNA Targets

(2007) Anders Gunnarsson et al.   NANO LETTERS

Flexible macromolecules attached to lipid bilayers: impact on fluidity, curvature, permeability and stability of the membranes

(2007) Christophe Tribet et al.   Soft Matter