Article
Chemistry, Applied
K. J. Anjaly, G. Avudaiappan, G. Smitha, K. Sreekumar
Summary: Three novel multifunctional polyether grafted dendritic solid supports were developed for organic synthesis via single step, grafting from, and hypergrafting strategies. Het-PG, with high functional group capacity and increased accessibility of functional sites, was found to be a versatile solid support for organic synthesis.
REACTIVE & FUNCTIONAL POLYMERS
(2021)
Article
Engineering, Chemical
Yun Zhao, Xiaogang Yu, Xin Wen, Yong Luo, Zhonghua Xiang, Jian-feng Chen
Summary: The scale-up synthesis of covalent organic frameworks (COFs) with uniform structure and properties is achieved using high-gravity intensified synthesis. The formation of COFBTC is improved synergically by alcoholic solvent and basic catalyst. High concentration and reaction temperature are beneficial for high production. The intensified mass and heat transfer at high-gravity promotes the scaling-up of COFBTC with homogeneous structures and properties.
Article
Chemistry, Applied
Yangjuan An, Junmin Wang, Sichang Jiang, Min Li, Shuofeng Li, Qianqian Wang, Lin Hao, Chun Wang, Zhi Wang, Junhong Zhou, Qiuhua Wu
Summary: PA-MOP, a magnetic nanoporous organic polymer based on natural proanthocyanidin, was synthesized and used for extracting neonicotinoid insecticides from various samples. The extraction mechanism is attributed to multiple interactions between PA-MOP and neonicotinoids, with hydrogen bonding, 7C-7C stacking, and electrostatic interactions playing major roles.
Article
Chemistry, Analytical
Dominika Kolodziej, Lukasz Sobczak, Krzysztof Gorynski
Summary: Polyamide noncoated device for adsorption-based microextraction (PANDA microextraction) is a new, easy to prepare, environmentally friendly, inexpensive, and efficient sample preparation method created entirely with the use of 3D printing. The method utilizes the extractive properties of unmodified polyamide and carbon fiber blends and is compared to thin-film microextraction (TFME). The results show that 3D printed supports can be successfully used as a cost-saving, environmentally friendly solution for TFME devices, with similar extraction yield and sometimes even better extraction efficacy.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Wenqian Kang, Sheng Chen, Xiong Wang, Guangquan Li, Xiaoyu Han, Minfeng Da
Summary: In this study, ionic liquid-modified porous organic polymers (IL-POPs) were successfully synthesized and used to immobilize metallocene catalysts for olefin polymerization. The prepared IL-POPs exhibited a wide range of pore characteristics, and the supported catalysts showed high activity and narrow molecular weight distribution. The resulting polyethylene had a high melting point and similar chemical composition distribution.
Article
Chemistry, Physical
Karolina Wieszczycka, Irmina Wojciechowska, Kinga Filipowiak, Tomasz Buchwald, Marek Nowicki, Patrycja Dudzinska, Beata Strzemiecka, Adam Voelkel
Summary: In this study, novel bifunctional iminepyridinium-silicas were fabricated for the effective removal of toxic metals from waste water. The synthesized materials showed high adsorption capacity for Pb(II), Cd(II) and Cu(II) and demonstrated excellent performance in terms of pH, contact time, and ability to withstand the presence of coexisting ions. Among the materials, MBr-D4IA exhibited the highest adsorption capacity for Pb(II) and Cd(II), while also co-extracting Cu(II) from synthetic waste solutions at a rate of 79%. These findings indicate the potential of these novel adsorbents for the treatment of wastewater contaminated with toxic metals.
APPLIED SURFACE SCIENCE
(2022)
Article
Chemistry, Multidisciplinary
Jet Yeo, Ludmila Peeva, Seoyeon Chung, Piers Gaffney, Daeok Kim, Carla Luciani, Sergey Tsukanov, Kevin Seibert, Michael Kopach, Fernando Albericio, Andrew Livingston
Summary: A one-pot liquid phase peptide synthesis was reported, which involved iterative addition of amino acids to a nanostar support and isolation of the growing peptide using organic solvent nanofiltration (OSN) after each synthesis cycle. The use of a three-armed and monodisperse nanostar support enabled efficient nanofiltration and real-time monitoring of each process cycle. This method allowed for more efficient peptide synthesis while maintaining the benefits of liquid phase synthesis.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Inorganic & Nuclear
Navneet Kaur, Randeep Kaur, Ranjeet Kaur, Shweta Rana
Summary: A novel benzothiazole-based compound was synthesized to fabricate fluorescent and redox active organic nanoparticles through nano re-precipitation method. The resulting nanoparticles, acting as a selective and sensitive sensor for Fe3+ ions in dual transduction mode, showed quenching of fluorescence intensity and an amplified stripping current response in the presence of Fe3+, making them suitable for in-field analysis.
INORGANIC CHEMISTRY COMMUNICATIONS
(2021)
Article
Chemistry, Analytical
Yuanfei Liu, Sunqi Shang, Wanjiao Wei, Yuefei Zhang, Wei Chen, Sheng Tang
Summary: In this study, an IL modified COF bonded silica composite material (IL-COF@SiO2) was successfully synthesized using a deep eutectic solvent as the reaction medium instead of organic solvent. The IL-COF@SiO2 composite material combines the separation ability of COF and the mass transfer function of porous silica. The introduction of IL provides better separation performance, demonstrating potential as a versatile liquid chromatographic separation material.
ANALYTICA CHIMICA ACTA
(2023)
Article
Environmental Sciences
Aparna Satsangi, Ankita Mangal, Awni Agarwal, Anita Lakhani, K. Maharaj Kumari
Summary: This study investigates the mechanism and chemistry of winter haze formation, focusing on aerosol composition and meteorological parameters during two consecutive winter seasons. The findings show that during haze episodes, there is a significant increase in PM2.5 concentrations, with carbonaceous aerosols and secondary inorganic aerosols playing a key role in the haze formation process.
ATMOSPHERIC POLLUTION RESEARCH
(2021)
Article
Energy & Fuels
Mariana Myriam Campos Fraga, Jonas Vogt, Bruno Lacerda de Oliveira Campos, Caroline Carriel Schmitt, Klaus Raffelt, Nicolaus Dahmen
Summary: This study evaluated the impact of different Nb2O5 polymorphs on the upgrading of pyrolysis oil and concluded that un- or low-temperature treated polymorphs showed higher activity and potential as catalyst supports. Furthermore, the nanostructured TT-Nb2O5 exhibited remarkable activity towards hydrogenation and hydrogenolysis, resulting in improved oil quality.
Article
Environmental Sciences
Frances Pauelsen, Sven Huppertsberg, Thomas P. Knepper, Daniel Zahn
Summary: Water-soluble polymers (WSPs) such as polyethylene oxide (PEO) are widely used and released into the aquatic environment, but there is a lack of analytical methods to study their occurrence. This study developed a method using size exclusion chromatography and mass spectrometry to quantify PEO and its derivatives in wastewater treatment plants (WWTPs) and surface water. The concentrations of PEO detected were relatively high, indicating potential risks in the aquatic environment. This method can help assess the burden and risk of high production volume chemicals like PEO.
SCIENCE OF THE TOTAL ENVIRONMENT
(2023)
Article
Chemistry, Multidisciplinary
Dmitry B. Eremin, Valery V. Fokin
Summary: Water significantly impacts organic reactions by speeding them up or altering their selectivity. Performing reactions on-water provides a unique opportunity to influence chemical reactivity in complex environments. The on-water switch in the formation of triazoles controlled by the dual spray shows a change in chemoselectivity.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2021)
Article
Biochemistry & Molecular Biology
Dahbia Yatoui, Philipp O. Tsvetkov, Romain La Rocca, Viktoriia E. Baksheeva, Diane Allegro, Gilles Breuzard, Geraldine Ferracci, Deborah Byrne, Francois Devred
Summary: Researchers have identified three zinc binding sites on Tau protein and found that zinc binding to these sites plays an important role in aggregation. Particularly, lack of zinc binding to the high affinity site in the repeat region prevents Tau protein from aggregating.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Sichang Jiang, Xufeng Meng, Mingming Xu, Min Li, Shuofeng Li, Qianqian Wang, Weihua Liu, Lin Hao, Junmin Wang, Chun Wang, Zhi Wang, Qiuhua Wu
Summary: A hydroxyl-functional magnetic porous organic polymer (Rut-MOP) was synthesized using natural rutin as a green monomer, and it exhibited high extraction capability for neonicotinoid insecticides. This Rut-MOP based method combined with high performance liquid chromatography was successfully applied for the sensitive determination of neonicotinoids in lemon juice and honey samples.
Article
Chemistry, Organic
Songhai Huang, Xiazhen Bao, Ying Fu, Yongxin Zhang, Zhengjun Quan, Congde Huo
ASIAN JOURNAL OF ORGANIC CHEMISTRY
(2020)
Article
Chemistry, Organic
Menghui Song, Hongyan Zhou, Ganggang Wang, Ben Ma, Yajing Jiang, Jingya Yang, Congde Huo, Xi-Cun Wang
Summary: A new visible-light-promoted transfer hydrogenation of azobenzenes has been developed, with the reactions proceeding smoothly in methanol at ambient temperature in the presence of B(2)pin(2). Azobenzenes with diverse functional groups were reduced to hydrazobenzenes with a high yield of up to 96%. Preliminary mechanistic studies suggest that the hydrogen atom comes from the solvent and the transformation occurs via a radical pathway.
JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Agriculture, Multidisciplinary
Xiazhen Bao, Xuehui Cao, Yong Yuan, Bo Zhou, Congde Huo
Summary: A highly efficient fluorescence probe CMQ was developed for the detection of sulfur dioxide in foods and biological systems, showing ultrafast response and low detection limit. Additionally, it was successfully applied for imaging in living cells and zebrafish.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2021)
Article
Chemistry, Organic
Jun Li, Yong Yuan, Xiazhen Bao, Tongzhi Sang, Jie Yang, Congde Huo
Summary: An intermolecular vicinal O-N difunctionalization reaction of olefins with oxime esters has been developed using energy transfer catalysis.
Article
Chemistry, Organic
Guozhe Guo, Yong Yuan, Xiazhen Bao, Xuehui Cao, Tongzhi Sang, Jiayuan Wang, Congde Huo
Summary: The study presents a novel visible-light induced redox-neutral decarboxylative cross coupling reaction, which successfully synthesized a variety of symmetrical and unsymmetrical 3,3'-bisindolylmethane derivatives from indole-3-acetic acid NHPI esters and indoles. Additionally, the reaction can be easily adapted for the preparation of a wide range of diarylmethane derivatives.
Article
Chemistry, Organic
Jiayuan Wang, Youwan Ye, Tongzhi Sang, Chenxing Zhou, Xiazhen Bao, Yong Yuan, Congde Huo
Summary: A general C(sp3)-H/C(sp3)-H dehydrogenative coupling strategy for the preparation of various natural or unnatural amino acids from readily available glycine derivatives and hydrocarbons is reported, which involves a combination of SET and HAT process.
Article
Chemistry, Applied
Lanlan Ou, Tongzhi Sang, Congde Huo
Summary: We presented a method to access quinoline-oxadiazole heterobiaryls. This method involves the oxidative (4+2)-cyclization/aromatization tandem reaction of N-aryl heteroaryl methanamines with alkenes or alkynes, catalyzed by copper under aerobic condition.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Organic
Tongzhi Sang, Chenxing Zhou, Jun Li, Xincong Liu, Yong Yuan, Xiazhen Bao, Xiaolong Zhao, Congde Huo
Summary: We report a visible-light-promoted approach for the anti-Markovnikov hydrooxygenation of unactivated alkenes. The protocol uses a cost-effective, bench-stable, and easy-to-handle oxime ester as the reagent, enabled by energy-transfer catalysis. This methodology exhibits excellent functional group tolerance and mild reaction conditions, making it suitable for the hydroesterification of pharmaceutically relevant molecule-derived alkenes.
Article
Chemistry, Organic
Tongzhi Sang, Jia Liang, Songhai Huang, Guozhe Guo, Jie Yang, Xiazhen Bao, Congde Huo
Summary: A facile and efficient aerobic oxidative (4 + 2)-cyclization/aromatization/lactonizationtandem reaction of N-aryl glycine esters with propargylalcohols to access quinoline-fused lactones is reported. The reactioncan be extended to homopropargylic alcohols too. The transformationis straightforward to perform under mild conditions and scalable,and both reaction components are readily available.
JOURNAL OF ORGANIC CHEMISTRY
(2023)
Article
Chemistry, Organic
Chengxian Hu, Dan Mou, Xi Zhang, Ying Fu, Congde Huo, Zhengyin Du
Summary: A Pd-catalyzed annulation method has been developed for the synthesis of 10H-indolo[1,2-a]indol-10-one derivatives via C-H bond activation and difluorocarbene transfer. The method features high reactivity and moderate to high yields.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2022)
Article
Chemistry, Organic
Guozhe Guo, Yong Yuan, Shuocheng Wan, Xuehui Cao, Yali Sun, Congde Huo
Summary: This study demonstrated for the first time that K2S2O8 promoted dehydrative cross-coupling reaction can synthesize a wide range of allyl sulfides, with broad substrate scopes and tolerance to various substrates, possibly involving a radical addition process.
ORGANIC CHEMISTRY FRONTIERS
(2021)
Article
Chemistry, Multidisciplinary
Jia Liang, Ying Fu, Xiazhen Bao, Lanlan Ou, Tongzhi Sang, Yong Yuan, Congde Huo
Summary: A new method for preparing alpha-cyano glycine derivatives through catalytic oxidative reaction using a copper catalyst and NFSI oxidant was reported, with broad substrate scope and mild reaction conditions. CuCl acted as a one-electron reductant and transition-metal catalyst, while NFSI served as a one-electron oxidant generating a N-centered radical as a H-abstractor.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Jiayuan Wang, Yingpeng Su, Zhengjun Quan, Jun Li, Jie Yang, Yong Yuan, Congde Huo
Summary: This method utilizes a visible-light-mediated aerobic alpha-alkylation reaction of glycine derivatives with alkyl boronic acids in the presence of a Ru/Cu catalyst system to efficiently produce a wide range of complex unnatural alpha-amino-acid derivatives. It features mild reaction conditions and broad substrate scope.
CHEMICAL COMMUNICATIONS
(2021)
Article
Chemistry, Multidisciplinary
Pengfei Niu, Jingya Yang, Yong Yuan, Yongxin Zhang, Chenxing Zhou, Xiazhen Bao, Congde Huo
Summary: In this study, a redox-neutral decarboxylative coupling reaction of heteroaryl methylamines with NHPI esters derived from aliphatic carboxylic acids has been developed. By employing a copper complex as a photocatalyst with blue LED irradiation, NHPI esters underwent one-electron reduction and heteroaryl methenamine derivatives underwent one-electron oxidation in one photo-redox catalytic cycle to form radical intermediates, respectively, followed by the recombination of these two radicals to form new C-C bonds. The methodology allows for the transformation of different kinds of heteroaromatic compounds as well as primary, secondary and tertiary alkyl carboxylic acids, and can be scaled up, with NHPI being recoverable and the reaction being conducted in a one-pot in situ activation manner.
Article
Chemistry, Organic
Jingya Yang, Ganggang Wang, Hongyan Zhou, Zhifeng Li, Ben Ma, Menghui Song, Rongxia Sun, Congde Huo
Summary: The visible-light-promoted O-H insertion reaction between 2-pyridones and alpha-aryldiazoacetates proceeds smoothly under mild and catalyst-free conditions, leading to a wide scope of O-alkylated 2-pyridones with perfect selectivity and good functional group tolerance, likely attributed to a photoinduced radical process.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2021)
Review
Chemistry, Multidisciplinary
Yikuan Liu, Xiaona Liu, An Su, Chengtao Gong, Shenwei Chen, Liwei Xia, Chengwei Zhang, Xiaohuan Tao, Yue Li, Yonghe Li, Tulai Sun, Mengru Bu, Wei Shao, Jia Zhao, Xiaonian Li, Yongwu Peng, Peng Guo, Yu Han, Yihan Zhu
Summary: Covalent organic frameworks are crystalline porous materials with designable structures and functions, which can acquire multifunctionalities and have versatile applications in gas separation/storage, catalysis, and optoelectronic devices.
CHEMICAL SOCIETY REVIEWS
(2024)
Review
Chemistry, Multidisciplinary
Heyang Zhang, Jo Vandesompele, Kevin Braeckmans, Stefaan C. De Smedt, Katrien Remaut
Summary: Gene therapy has the potential to revolutionize the treatment of inherited and acquired diseases, but its success rate is currently limited. This review focuses on the obstacles faced by gene therapies in the human body, such as nucleic acid degradation by abundant nucleases, and discusses strategies to reduce degradation and methods to assess nucleic acid integrity.
CHEMICAL SOCIETY REVIEWS
(2024)
Review
Chemistry, Multidisciplinary
Chenxi Duan, Chunming Cui
Summary: Low valent group 14 compounds with diazaborolyl substituents exhibit unique structures and reactivity due to the combination of sigma-electron donation and steric hindrance. The modulation of the HOMO-LUMO gap by the diazaborolyl substituents results in novel reaction patterns in the activation of small molecules and inert chemical bonds.
CHEMICAL SOCIETY REVIEWS
(2024)
Review
Chemistry, Multidisciplinary
David E. Salazar Marcano, Nada D. Savic, Kilian Declerck, Shorok A. M. Abdelhameed, Tatjana N. Parac-Vogt
Summary: Metal-oxo clusters have great potential in various fields and can react with biomolecules, making them promising for applications in disease treatment and energy development. They can also be used in the development of inorganic drugs and bioanalytical tools.
CHEMICAL SOCIETY REVIEWS
(2024)
Review
Chemistry, Multidisciplinary
Lana K. Moree, Logan A. V. Faulkner, James D. Crowley
Summary: In this tutorial review, the general methods for synthesizing heterometallic metallosupramolecular architectures (MSAs), specifically heterometallic cages, are examined. The intrinsic properties and potential applications of these cages as host-guest systems and reaction catalysts are discussed.
CHEMICAL SOCIETY REVIEWS
(2024)