期刊
CHEMICAL PHYSICS LETTERS
卷 489, 期 1-3, 页码 121-126出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.cplett.2010.02.053
关键词
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资金
- NSF [IIS-0514361]
- National MASINT Management Office (NMMO)
- NIH [GM072897]
We used surface-enhanced Raman spectroscopy (SERS) to detect binding events between streptavidin and biotinylated lipid bilayers. The binding events took place at the surface between micro-fluidic channels and anodized aluminum oxide (AAO) with the latter serving as substrates. The bilayers were incorporated in the substrate pores. It was revealed that non-bound molecules were easily washed away and that large suspended cells (Salmonella enterica) are less likely to interfere with the monitoring process: when focusing to the lower surface of the channel, one may resolve mostly the bound molecules. (C) 2010 Elsevier B.V. All rights reserved.
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