Article
Engineering, Chemical
Nicolin Govender, Rafal Kobylka, Johannes Khinast
Summary: The blending of granular materials with different morphologies in industrial processes is unpredictable. Discrete element method simulations using polyhedral particles were used to study the effect of cohesion and particle shape in a rotating drum. Results showed that symmetric polyhedral shapes had the best mixing, while irregular shapes had the worst. Mixing improved with increasing cohesive particle size. Equipment geometry and rotation speed also significantly affected mixing.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Engineering, Chemical
Marv J. Khala, Colin Hare, Chuan-Yu Wu, Navin Venugopal, Martin J. Murtagh, Tim Freeman
Summary: The study investigates mixing and segregation of binary mixtures of glass beads and/or resin particles based on density and size differences using a new FT4 methodology. Results show that the mixing index increases with density and size ratio, with flow energy and torque variation related to mixture components' mixing and segregation. DEM numerical analysis reveals that mixing and segregation occur differently in non-cohesive and cohesive systems under various stress conditions.
Article
Computer Science, Software Engineering
Vasyl Skorych, Maksym Dosta
Summary: The efficiency of simulations using the discrete element method (DEM) has been significantly improved with a novel computational strategy that focuses on parallel execution on both CPU and GPU, resulting in decreased computational time and more efficient utilization of available resources. Furthermore, the overall energy requirement for this strategy does not exceed that of conventional sequential CPU-GPU computations.
CONCURRENCY AND COMPUTATION-PRACTICE & EXPERIENCE
(2022)
Article
Chemistry, Analytical
Ernesto Fontana, Dario Lodi Rizzini
Summary: This paper presents an efficient variant of the ARS algorithm called Cud-ARS for 2D registration. It utilizes parallel computation on GPUs to speed up the execution time and introduces a global branch-and-bound method for translation estimation. Experimental results demonstrate that this method enables faster and more accurate localization and mapping, particularly in rotation estimation.
Review
Computer Science, Interdisciplinary Applications
Yashwanth Kumar Gujjala, Hyung-Mok Kim, Dong-Woo Ryu
Summary: This study summarizes the research on solving geotechnical problems using general-purpose computing of graphical processing units and identifies the combination of GPU-based discrete element method and combined finite discrete element method as the most popular techniques.
ARCHIVES OF COMPUTATIONAL METHODS IN ENGINEERING
(2023)
Article
Engineering, Chemical
Chao Zheng, Liang Li, Bernardus Joseph Nitert, Nicolin Govender, Thomas Chamberlain, Ling Zhang, Chuan-Yu Wu
Summary: The study uses GPU-enhanced DEM to analyze granular dynamics in a continuous blender. Results show most powder distributes in the middle and lower regions, higher impeller speed leads to smaller hold-up mass and shorter residence time, and maximum blade passes are achieved at intermediate speed.
Article
Computer Science, Software Engineering
Yuxuan Hou, Zhong Ren, Qiming Hou, Yubo Tao, Yankai Jiang, Wei Chen
Summary: Neuron tracing, or reconstruction, is crucial for studying neuronal circuits and brain mechanisms. We present InstantTrace, a novel framework that utilizes parallel tracing on GPUs and achieves a more than 20x speed boost compared to state-of-the-art methods, while maintaining comparable reconstruction quality. The framework takes advantage of the sparse feature and tree structure of the neuron image and parallelizes all stages of the tracing pipeline on GPU. A test on a whole mouse brain OM Image demonstrated that our framework can achieve a preliminary reconstruction within 1 hour on a single GPU, which is an order of magnitude faster than existing methods. This framework has the potential to significantly improve the efficiency of the neuron tracing process and provide instant preliminary results for manual verification and refinement.
Article
Computer Science, Interdisciplinary Applications
Yu Zhang, Shaohao Hou, Shengjie Di, Zaobao Liu, Yifan Xu
Summary: A high-performance DEM-SPH coupling method based on GPU parallel acceleration technique is proposed for landslide surge simulation. The accuracy and efficiency of the method are validated through simulation experiments, and the effects of different particle diameters and surge climb heights on the simulation results are analyzed.
COMPUTERS AND GEOTECHNICS
(2023)
Article
Engineering, Chemical
Reddi Kamesh, Shiva Vaddagani, C. Sumana, Srikanth R. Gopireddy, Nora A. Urbanetz, K. Yamuna Rani
Summary: In this study, a six-directional sampling method (SDSM) and corresponding mixing indices (SDS-mMI) based on SDSM were proposed for assessing solids blending performance in DEM simulations. The proposed method divided the blender into small grids and accumulated the mass and mass contributions of each particle type by moving in six different directions. The evaluation of the proposed approach was conducted on two typical blenders and compared with other indices.
Article
Chemistry, Analytical
Gaogao Liu, Wenbo Yang, Peng Li, Guodong Qin, Jingjing Cai, Youming Wang, Shuai Wang, Ning Yue, Dongjie Huang
Summary: This paper focuses on the time division signal processing flow for MIMO radar and proposes an improved algorithm to enhance its processing speed. A parallel simulation system based on CPU/GPU architecture is introduced, which performs significantly faster than serial computing equipment and achieves satisfactory acceleration effects.
Article
Nuclear Science & Technology
J. M. S. Mendes, A. Heimlich, A. M. M. De Lima, F. C. Silva
Summary: An algorithm for solving the constitutive equations of the fourth-order Nodal Expansion Method (NEM) in parallel using GPU with quadratic transverse leakage has been proposed. The algorithm, implemented in CUDA language, showed comparable accuracy and reduced execution time compared to the CNFR code. This algorithm and the developed program have potential use in the optimization process of nuclear fuel reload patterns.
NUCLEAR ENGINEERING AND DESIGN
(2024)
Article
Engineering, Chemical
Nicolin Govender
Summary: This paper utilizes the advances in GPU computing via the Blaze-DEM code to study the effect of particle shape on heat transfer in a rotating drum. The results show that shape irregularity has the greatest impact on heat conduction, with non-symmetric shapes exhibiting better heat transfer performance. Furthermore, there is a linear trend of system temperature with both RPM and fill level.
CHEMICAL ENGINEERING SCIENCE
(2022)
Article
Computer Science, Artificial Intelligence
Narcis Coll, Marta Fort, Moises Saus
Summary: This study presents a system for determining the optimal locations for k disk-like services to maximize the coverage of a demand region. The study focuses on the facility location field and addresses the challenge of locating multiple services efficiently. The proposed system utilizes a parallel simulated annealing optimization technique to provide good enough solutions within reasonable running times.
EXPERT SYSTEMS WITH APPLICATIONS
(2022)
Article
Engineering, Chemical
C. Hare, M. Ghadiri, Chuan-Yu Wu
Summary: The study compared two DEM-PBM approaches, one direct and one indirect, for predicting the size distribution of granules after dry compaction and milling. It was found that the direct approach showed reasonable agreement with experimental data, while accounting for material strength and loading conditions of fragments in the mill.
Article
Computer Science, Theory & Methods
Xin He, Yapeng Yao, Zhiwen Chen, Jianhua Sun, Hao Chen
Summary: This paper proposes a parallel A* search algorithm DA* based on a multi-GPU architecture, which efficiently accelerates the A* algorithm through effective graph partitioning and data communication strategies. The use of multiple priority queues enables parallel computation on multiple GPUs.
FUTURE GENERATION COMPUTER SYSTEMS-THE INTERNATIONAL JOURNAL OF ESCIENCE
(2021)
Article
Chemistry, Medicinal
Eva Faulhammer, Julia Kruisz, Otto Scheibelhofer, Jakob Rehrl, Andreas Witschnigg, Johannes G. Khinast
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2020)
Article
Chemistry, Applied
Manuel Zettl, Manuel Kreimer, Isabella Aigner, Thomas Mannschott, Peter van der Wel, Johannes Khinast, Markus Krumme
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2020)
Article
Engineering, Chemical
Luca Orefice, Johannes G. Khinast
Article
Engineering, Chemical
Otto Scheibelhofer, Julia Kruisz, Jakob Rehrl, Eva Faulhammer, Andreas Witschnigg, Johannes G. Khinast
Article
Pharmacology & Pharmacy
Jakob Rehrl, Stephan Sacher, Martin Horn, Johannes Khinast
Article
Engineering, Chemical
Sara Fathollahi, Eva Faulhammer, Benjamin J. Glasser, Johannes G. Khinast
ADVANCED POWDER TECHNOLOGY
(2020)
Article
Biochemistry & Molecular Biology
Wajiha Farha Faqar-Uz-Zaman, Katrin G. Schmidt, Dominique Thomas, Josef M. Pfeilschifter, Heinfried H. Radeke, Anja Schwiebs
Summary: The study suggests that by interfering with SGPL1 expression, colorectal cancer cells can be induced to partially redifferentiate towards normal colon epithelial cells, reducing their malignant potential.
Article
Multidisciplinary Sciences
Valeska Helfinger, Florian Freiherr von Gall, Nina Henke, Michael M. Kunze, Tobias Schmid, Flavia Rezende, Juliana Heidler, Ilka Wittig, Heinfried H. Radeke, Viola Marschall, Karen Anderson, Ajay M. Shah, Simone Fulda, Bernhard Bruene, Ralf P. Brandes, Katrin Schroeder
Summary: Reactive oxygen species (ROS) have dual effects in cells, causing cellular damage while also maintaining cell homeostasis. Nox4 plays a crucial role in cell differentiation and inflammation prevention by producing low levels of H2O2 continuously. The absence of Nox4 promotes tumor formation and impairs DNA damage recognition, highlighting the importance of moderate ROS production in preventing cancer initiation.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Biochemistry & Molecular Biology
Anja Schwiebs, Farha Faqar-Uz-Zaman, Martina Herrero San Juan, Heinfried H. Radeke
Summary: SGPL1 knockout mice showed absence of anti-Ki-67 staining in the stem cell niche under disease conditions, along with increased FOXO3 and decreased CDK2 activity. SGPL1(-/-M.Ex1) cells exhibited a similar increase in FOXO3 but no proliferation arrest, albeit with suppressed PDK1/AKT signaling pathway, prolonged G1-phase, and reduced stem cell markers. This suggests a new function of SGPL1 in stemness during colorectal cancer progression.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2021)
Article
Immunology
Tobias Burkard, Caroline Dreis, Martina Herrero San Juan, Meik Huhn, Andreas Weigert, Josef M. Pfeilschifter, Heinfried H. Radeke
Summary: The immune response to cancer can be disrupted by an immunosuppressive tumor microenvironment, including infiltrating regulatory T lymphocytes and metabolic stress. Molecules like IL-33 and S1P play a role in controlling T lymphocyte differentiation and migration. Nutrient deprivation can promote CD8(Low) T lymphocytes and limit cytotoxic effector functions.
FRONTIERS IN IMMUNOLOGY
(2021)
Letter
Gastroenterology & Hepatology
Heinfried H. Radeke, Juergen Stein
ALIMENTARY PHARMACOLOGY & THERAPEUTICS
(2022)
Article
Environmental Sciences
Annkatrin Weber, Anja Schwiebs, Helene Solhaug, Jorgen Stenvik, Asbjorn M. Nilsen, Martin Wagner, Borna Relja, Heinfried H. Radeke
Summary: Exposure to nanoplastics can induce inflammatory responses in human immune cells, with specific polymers and particle shapes having significant effects.
ENVIRONMENT INTERNATIONAL
(2022)
Article
Pharmacology & Pharmacy
Larisa Bora, Tobias Burkard, Martina Herrero San Juan, Heinfried H. Radeke, Ana Maria Mut, Lavinia Lia Vlaia, Ioana Zinuca Magyari-Pavel, Zorita Diaconeasa, Sonia Socaci, Florin Borcan, Brigitta Kis, Delia Muntean, Cristina Adriana Dehelean, Corina Danciu
Summary: This study presents the phytochemical and biological evaluation of Origanum vulgare L. essential oil (OEO) formulated as polymeric micelles for the management of skin tags. The results showed that the OEO-loaded poloxamer-based binary hydrogel (OEO-PbH) exhibited skin compatibility and inhibited migration and proliferation of HaCaT cells. Furthermore, OEO-PbH did not have a harmful effect on the viability of dendritic cells.
Article
Oncology
Tobias Burkard, Martina Herrero San Juan, Caroline Dreis, Anastasiia Kiprina, Dmitry Namgaladze, Kai Siebenbrodt, Sebastian Luger, Christian Foerch, Josef M. Pfeilschifter, Andreas Weigert, Heinfried H. Radeke
Summary: Functionally distinct cytotoxic T lymphocytes can be identified based on their expression of CD8, playing opposing roles in the tumor microenvironment and autoimmune diseases such as multiple sclerosis. The presence of CD8(Low) T cells correlated with poor prognosis and enhanced cancer progression, while a reduced frequency of these cells was found in relapse multiple sclerosis patients compared to healthy subjects during immune cell starvation in vitro.
CLINICAL AND TRANSLATIONAL MEDICINE
(2022)
Article
Integrative & Complementary Medicine
Brigitta Kis, Ioana Zinuca Pavel, Stefana Avram, Elena Alina Moaca, Martina Herrero San Juan, Anja Schwiebs, Heinfried H. Radeke, Delia Muntean, Zorita Diaconeasa, Daliana Minda, Camelia Oprean, Florina Bojin, Cristina Adriana Dehelean, Codruta Soica, Corina Danciu
Summary: This study evaluates the antioxidant potential, antimicrobial activity, in vitro anticancer effect, antiangiogenic effect, and immunomodulatory potential of Populus nigra L. bud extract collected from the western part of Romania. The results show that the extract has significant antioxidant and antimicrobial activity, inhibits tumor cell viability, suppresses angiogenesis, and modulates immune response.
BMC COMPLEMENTARY MEDICINE AND THERAPIES
(2022)
Article
Engineering, Chemical
Qing Han, Mengqing Shi, Linkai Han, Di Liu, Mingwei Tong, Yuxin Xie, Zhonghua Xiang
Summary: Developing highly efficient bifunctional oxygen electrocatalysts is crucial for zinc-air flow batteries. Metal-organic frameworks (MOFs) and covalent organic polymers (COPs) have emerged as promising alternatives due to their designable and controllable atomic-level structures. However, their catalytic performances are limited by conductivity and catalytic activity. In this study, nanosheet FeNi-MOF and iron phthalocyanine rich COP hybrid materials are assembled through the pi-pi stacking effect to create highly efficient bifunctional electrocatalysts. The resulting catalyst exhibits superior catalytic performance and stability, making it a promising candidate for zinc-air flow batteries.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Daria Grigorash, Dmytro Mihrin, Rene Wugt Larsen, Erling H. Stenby, Wei Yan
Summary: The article introduces a new approach to describe the cross-association between molecules, allowing for the simulation of weakly bound molecular complexes with different conformations in mixtures. By incorporating this approach into the equation of state, accurate predictions of vapor-liquid equilibrium and liquid-liquid equilibrium can be made. The new method is validated through experiments on alcohol and acid mixtures, with the results compared to experimental data, demonstrating its accuracy and reliability.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Mohammed Al-Sharabi, Daniel Markl, Vincenzino Vivacqua, Prince Bawuah, Natalie Maclean, Andrew P. E. York, Axel Zeitler
Summary: This study used terahertz pulsed imaging to investigate the transport process of different solvents into ceramic catalytic materials. The results showed that the heating rate of the samples influenced the water transport rate, while the viscosity of 1-octanol slowed down its transport.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Chukwunonso Anyaoku, Sati Bhattacharya, Rajarathinam Parthasarathy
Summary: This study aimed to enhance understanding of settling dynamics in viscoelastic fluids by developing a semi-empirical correlation and a dimensionless ratio, which accurately described the characteristics of settling suspensions.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Antti I. Koponen, Janika Viitala, Atsushi Tanaka, Baranivignesh Prakash, Olli-Ville Laukkanen, Ari Jasberg
Summary: This study focuses on the development of foam application chemicals for the paper and board industry. The research explores the rheology of the polyvinyl alcohol foam used in the process. Measurements were conducted to determine the foam viscosity and slip flow. The results suggest that slip flow contributes significantly to the total flow rate, and the obtained viscosity and slip models provide a solid foundation for industrial processes.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Dalei Sun, Jinghui Cai, Yating Yang, Zhiwu Liang
Summary: In this study, Fe-doped alpha-Bi2O3 catalysts with different Fe/Bi molar ratios were synthesized and utilized in the carbonylation of isobutyl amine with CO2. The results showed that Fe doping significantly enhanced the catalytic abilities of alpha-Bi2O3.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Yuan Tian, Xinxin Wang, Yanrong Liu, Wenping Hu
Summary: This paper predicts the solubility of nitrogen gas in ionic liquids (ILs) using two quantitative structure-property relationship (QSPR) models. By combining machine learning methods and ionic fragments contribution method, the accuracy and reliability of the prediction models are improved.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Liwang Wang, Wei Liu, Pan Yang, Yulong Chang, Xiaoxu Duan, Lingyu Xiao, Yaoming Hu, Jiwei Wu, Liang Ma, Hualin Wang
Summary: This study investigates the effective phase interfacial area (ae) of hydro-jet cyclones at different injection angles. The results show that a 45 degrees upward incidence angle yields the most favorable flow field characteristics for efficient mass transfer. The significant enhancement in ae of the hydro-jet cyclones offers the advantage of reducing equipment volume and cost savings.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Chuanjun Wu, Jiangzhi Chen, Jiyue Sun, I-Ming Chou, Shenghua Mei, Juezhi Lin, Lei Jiang
Summary: In this study, the solubility of H2S hydrate in water was measured using Raman spectroscopy. The results showed that the solubility increases with temperature under certain equilibrium conditions, and the solubility also depends on pressure and temperature under different equilibrium conditions. A thermodynamic model based on the van der Waals-Platteeuw theory was developed to predict the solubility, demonstrating its accuracy.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Lorenzo Brivio, Serena Meini, Mattia Sponchioni, Davide Moscatelli
Summary: This study investigates the influence of three main parameters and proposes a kinetic model to predict the optimal operating conditions for high yield of dimethyl terephthalate (DMT) in the chemical recycling process of polyethylene terephthalate (PET).
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Hongju Lin, Fanhui Liao, Yanchang Chu, Mingyu Xie, Lun Pan, Yuanyuan Wang, Lijian Leng, Donghai Xu, Le Yang, Gangfeng Ouyang
Summary: A honeycomb NiCo/C-Na catalyst with a micro-meso-macroporous structure has been fabricated and shown to have significantly higher catalytic activity for the decarboxylation of fatty acids. It also proves to be efficient in upgrading sludge HTL bio-crude, resulting in a biofuel with decreased viscosity and increased density.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Xiaoxian Li, Rui Li, Min Lin, Mingde Yang, Yulong Wu
Summary: A series of coated non-noble metal porous carbon catalysts were synthesized and applied to the aqueous-phase deoxygenation of algal bio-oil. One of the catalysts showed excellent deoxygenation selectivity and catalytic activity at 250 degrees C. The catalyst exhibited good hydrothermal stability and the reaction mechanism was proposed based on product analysis and active site analysis.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
M. V. Chudakova, M. V. Popov, P. A. Korovchenko, E. O. Pentsak, A. R. Latypova, P. B. Kurmashov, A. A. Pimenov, E. A. Tsilimbaeva, I. S. Levin, A. G. Bannov, A. V. Kleymenov
Summary: A series of catalysts with different potassium contents were prepared using solution combustion synthesis and characterized using various techniques. The results showed that the potassium content affected the phase composition and texture of the catalysts. The addition of a small amount of potassium resulted in a change in particle size distribution, leading to higher hydrogen yield. The Ni-1%K2O/Al2O3 catalyst exhibited the highest hydrogen yield at temperatures of 675 and 750 degrees Celsius.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Aliakbar Roosta, Nima Rezaei
Summary: In this study, we modified the electrolyte cubic plus association equation of state (e-CPA EoS) and integrated it with two electrical conductivity models to estimate the electrical conductivity of 11 monovalent electrolyte solutions in water. The modified e-CPA model demonstrated better performance and the hybridization with electrical conductivity models resulted in two predictive models for estimating the electrical conduction of dilute and concentrated electrolyte solutions. These predictive models showed relative average percentage deviations (AARD) of 11.15% and 13.87% over wide ranges of temperature and electrolyte concentration.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Haoren Niu, Jianzheng Wang, Qingzhu Jia, Qiang Wang, Jin Zhao, Fangyou Yan
Summary: A study developed two quantitative structure-property relationship models for the complexation performance of alpha- and beta-cyclodextrins and validated their stability and predictive ability through internal and external validation. The models showed robustness and satisfactory performance, as demonstrated by the experimental results and model validations. These models can effectively predict the binding constants between cyclodextrins and various types of molecules, providing valuable tools for cyclodextrin design.
CHEMICAL ENGINEERING SCIENCE
(2024)