Article
Engineering, Chemical
Tong Zhou, Chunzhao Tu, Ya Sun, Linan Ji, Chuangxian Bian, Xiaohua Lu, Changsong Wang
Summary: The experimental determination of the solubility, metastable zone width, and induction time of thiourea in the cooling crystallization process showed the effects under different conditions. The study indicated that homogeneous nucleation could occur at high supersaturation, while heterogeneous nucleation was more likely to occur at low supersaturation.
CHINESE JOURNAL OF CHEMICAL ENGINEERING
(2021)
Article
Engineering, Chemical
Lan Fang, Zhenguo Gao, Zhenjie Gao, Wenfeng Huang, Xuxing Wan, Sohrab Rohani, Junbo Gong
Summary: This study presents the successful continuous preparation of pure metastable crystal Form III of APZ using ultrasound and slug-assisted tubular crystallizers, providing a solution to the difficulty of reproducibly obtaining metastable polymorphs in traditional batch crystallizers.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Engineering, Chemical
Shuai Wang, Jing Zhao, Ming Li, Renzhong Qiao, Chao Li
Summary: In this study, four new polymorphs of tazobactam sodium were prepared by antisolvent methods, and the crystallization process was optimized. A single crystal of tazobactam sodium in water/ethanol solvent was obtained and its structure was analyzed. The reactive crystallization process, including amine reagent, salt-forming agent, and solvent system, was explored and optimized. This research provides more options for pharmaceutical polymorphs of tazobactam sodium, supporting the industrial production and transportation of the drug.
CHEMICAL ENGINEERING SCIENCE
(2023)
Article
Pharmacology & Pharmacy
Andrew Megarry, Hakan Wikstrom, Frida Bilen, Johan Remmelgas, Alexander Liljeblad, Pirjo Tajarobi
Summary: In this study, five well-known excipients and a model drug substance with different particle properties were selected to understand the impact of different blends. Two pilot-scale unvented IBCs were used, and the discharge rates and powder behavior were measured and recorded. The videos showed that air burst was necessary for powder flow, and the air flow inside the IBC was strong. Good indicators of flow/no flow were found, but there was a linear correlation between orifice flow and IBC discharge rate for predicting the rate.
INTERNATIONAL JOURNAL OF PHARMACEUTICS
(2023)
Article
Crystallography
Josia Tonn, Aishe Grotjohann, Christian Kocks, Andreas Jupke
Summary: Scandium, a critical raw material according to the EU, has low availability but increasing demand. Bauxite residue can be a potential European source. A novel anti-solvent crystallization process is developed to extract scandium from the residue, but it faces challenges in solid-liquid separation due to the formation of small crystals. By studying nucleation kinetics and varying operating parameters, the boundaries for controlling the crystallization process and crystal growth are explored.
Article
Biochemistry & Molecular Biology
Lie-Ding Shiau
Summary: A linearized integral model is used in this study to determine the interfacial energy and pre-exponential factor. The results show that the calculated values from different methods are consistent for the studied systems.
Article
Astronomy & Astrophysics
Christopher W. Stubbs
Summary: The method described in the text utilizes strobed emitters along the optical path to measure the impact of local refractive index perturbations on image quality. This approach allows for direct measurement of image motion and scintillation, separate from the seeing induced by the atmosphere above the dome.
MONTHLY NOTICES OF THE ROYAL ASTRONOMICAL SOCIETY
(2021)
Article
Crystallography
Zhirong Chen, Rongfan Zhou, Hong Yin, Shenfeng Yuan
Summary: The metastable zone width (MSZW) of DL-methionine aqueous solution for unseeded batch crystallization was measured by turbidity method. The spontaneous nucleation curves at different stirring rates and cooling rates were obtained. The results show that the increase in saturation temperature and stirring rate makes the MSZW narrower, while the increase in cooling rate widens the MSZW due to a time lag between nucleation and turbidity detection. These data are important for controlling crystallization in production and the nucleation kinetics was also studied.
JOURNAL OF CRYSTAL GROWTH
(2023)
Article
Chemistry, Analytical
Yuliya Generalova, Nadezhda Sipkina, Galina Alekseeva
Summary: The new compound malaben exhibits pronounced activity in treating non-alcoholic fatty liver disease and could potentially be used as a drug. Various impurities in the malaben sample were studied and identified using electrophoretic separation and HPLC-ESI/MS analysis techniques, providing structural elucidation for some of the impurities.
MICROCHEMICAL JOURNAL
(2021)
Article
Crystallography
Christian Kocks, Christina Maria Krekel, Marcel Gausmann, Andreas Jupke
Summary: Electrified downstream processes reduce waste salt generation and enhance the attractiveness of biotechnological production. Understanding the metastable zone width is crucial for designing and controlling electrochemically induced crystallization processes.
Article
Crystallography
Keshra Sangwal
Summary: Based on classical nucleation theory, final equations regarding the metastable zone width were derived using three deterministic approaches, which were then applied to analyze experimental data from different systems. The analysis compared and discussed trends in nucleation kinetic parameters values obtained from the deterministic integral nucleation model and the conventional stochastic theory. Results showed that the solute-supply approach could explain the dependency of solutions' Delta T-m values on cooling rate at different saturation temperatures and estimate nucleation parameters, while relatively low values of the solid-solution interfacial solution gamma(eff) suggested crystallization by heterogeneous nucleation. The nature of nucleation encountered in the MSZW measurements by the polythermal method was also discussed.
JOURNAL OF CRYSTAL GROWTH
(2021)
Article
Chemistry, Multidisciplinary
Anindita Saha, Aadil A. Ahangar, Aijaz A. Dar, Satyanarayana Thirunahari, Jose V. Parambil
Summary: Cocrystallization in pharmaceuticals offers potential to modify APIs, but scaling up the process is challenging. This review addresses the barriers and proposes a decision tree to assist researchers in scaling up cocrystal production using established crystallization techniques. It emphasizes the importance of phase diagrams and discusses the effects of operating parameters on process kinetics. It also covers intermolecular interactions, cocrystallization methods, and quality control in pharmaceuticals. Design of Experiment and Quality by Design are highlighted for efficient scaling up of cocrystallization, bringing potential materials to the market.
CRYSTAL GROWTH & DESIGN
(2023)
Article
Chemistry, Applied
Oguz Ozbek
Summary: A novel potassium selective potentiometric sensor was developed for potassium analysis in various samples. The sensor exhibited a low detection limit, short response time, and high stability.
JOURNAL OF FOOD COMPOSITION AND ANALYSIS
(2023)
Article
Agricultural Engineering
Anastasia Ktenioudaki, Carlos A. Esquerre, Cecilia M. Do Nascimento Nunes, Colm P. O'Donnell
Summary: This study aimed to develop a non-destructive system using hyperspectral imaging technology for accurate estimation of shelf-life of strawberries. Prediction models were developed for other quality attributes and biochemical properties, supporting the drive for zero waste in the food supply chain.
BIOSYSTEMS ENGINEERING
(2022)
Article
Food Science & Technology
Joe Garvin, Feras Abushakra, Zachary Choffin, Bayley Shiver, Yu Gan, Lingyan Kong, Nathan Jeong
Summary: This paper proposes a novel microwave imaging system for detecting the ripeness of watermelon as a proof of concept. The design utilizes a circular array with 10 Coplanar Vivaldi antennas offering wide bandwidth, high gain, and high efficiency. S-parameters between antennas are quickly collected via automated channel switching for fast image generation. Comparisons with sample cross-sections show distinct differences in image characteristics based on watermelon maturity. Sugar concentration of unripe and ripe watermelon is also measured and plotted for further validation of the imaging technique.
CURRENT RESEARCH IN FOOD SCIENCE
(2023)
Article
Engineering, Chemical
Levente L. Simon
Article
Engineering, Chemical
Levente L. Simon, Konrad Hungerbuhler
CHEMICAL ENGINEERING & TECHNOLOGY
(2009)
Article
Energy & Fuels
Levente L. Simon, Hajnalka Kencse, Konrad Hungerbuhler
CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION
(2009)
Article
Engineering, Environmental
Levente L. Simon, Zoltan K. Nagy, Konrad Hungerbuhler
CHEMICAL ENGINEERING JOURNAL
(2009)
Article
Engineering, Environmental
Levente L. Simon, Konrad Hungerbuhler
CHEMICAL ENGINEERING JOURNAL
(2010)
Article
Engineering, Chemical
Levente L. Simon, Yannick Elias, Graeme Puxty, Yuli Artanto, Konrad Hungerbuhler
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2011)
Article
Engineering, Chemical
L. L. Simon, T. Merz, S. Dubuis, A. Lieb, K. Hungerbuhler
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2012)
Article
Engineering, Chemical
Zoltan K. Nagy, Gilles Fevotte, Herman Kramer, Levente L. Simon
CHEMICAL ENGINEERING RESEARCH & DESIGN
(2013)
Article
Engineering, Chemical
Levente L. Simon, Kaoutar Abbou Oucherif, Zoltan K. Nagy, Konrad Hungerbuhler
CHEMICAL ENGINEERING SCIENCE
(2010)
Article
Engineering, Chemical
Levente L. Simon, Kaoutar Abbou Oucherif, Zoltan K. Nagy, Konrad Hungerbuhler
INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH
(2010)
Article
Chemistry, Applied
Levente L. Simon, Zoltan K. Nagy, Konrad Hungerbuhler
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2009)
Review
Biotechnology & Applied Microbiology
Levente L. Simon, Anton A. Kiss, Jan Cornevin, Rafiqul Gani
CURRENT OPINION IN CHEMICAL ENGINEERING
(2019)
Article
Chemistry, Applied
Levente L. Simon, Michael Dieckmann, Alan Robinson, Thomas Vent-Schmidt, Dominique Marantelli, Ralf Kohlbrenner, Alexandre Saint-Dizier, Denis Gribkov, Jean-Philippe Krieger
Summary: This paper presents recent innovation activities related to the implementation of LED-based photochemical reaction technology at kilolab and production scales, and investigates the capital expenditure uncertainty estimation of photochemical lamps, finding it to be within 15-30% at two standard deviations.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2021)
Article
Chemistry, Applied
Alan Robinson, Michael Dieckmann, Jean-Philippe Krieger, Thomas Vent-Schmidt, Dominique Marantelli, Ralf Kohlbrenner, Denis Gribkov, Levente L. Simon, David Austrup, Alexandre Rod, Christian G. Bochet
Summary: A visible light-promoted C-N coupling method was developed for forging the central C-N bond of an agrochemical intermediate. Mechanistic studies showed that selective coupling was achieved through a radical pathway induced by the combination of light and oxygen, leading to successful scale-up to initial 20L and then 1.2m³.
ORGANIC PROCESS RESEARCH & DEVELOPMENT
(2021)
Correction
Biotechnology & Applied Microbiology
Levente L. Simon, Anton A. Kiss, Jan Cornevin, Rafiqul Gani
CURRENT OPINION IN CHEMICAL ENGINEERING
(2021)
Article
Engineering, Chemical
Qing Han, Mengqing Shi, Linkai Han, Di Liu, Mingwei Tong, Yuxin Xie, Zhonghua Xiang
Summary: Developing highly efficient bifunctional oxygen electrocatalysts is crucial for zinc-air flow batteries. Metal-organic frameworks (MOFs) and covalent organic polymers (COPs) have emerged as promising alternatives due to their designable and controllable atomic-level structures. However, their catalytic performances are limited by conductivity and catalytic activity. In this study, nanosheet FeNi-MOF and iron phthalocyanine rich COP hybrid materials are assembled through the pi-pi stacking effect to create highly efficient bifunctional electrocatalysts. The resulting catalyst exhibits superior catalytic performance and stability, making it a promising candidate for zinc-air flow batteries.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Daria Grigorash, Dmytro Mihrin, Rene Wugt Larsen, Erling H. Stenby, Wei Yan
Summary: The article introduces a new approach to describe the cross-association between molecules, allowing for the simulation of weakly bound molecular complexes with different conformations in mixtures. By incorporating this approach into the equation of state, accurate predictions of vapor-liquid equilibrium and liquid-liquid equilibrium can be made. The new method is validated through experiments on alcohol and acid mixtures, with the results compared to experimental data, demonstrating its accuracy and reliability.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Mohammed Al-Sharabi, Daniel Markl, Vincenzino Vivacqua, Prince Bawuah, Natalie Maclean, Andrew P. E. York, Axel Zeitler
Summary: This study used terahertz pulsed imaging to investigate the transport process of different solvents into ceramic catalytic materials. The results showed that the heating rate of the samples influenced the water transport rate, while the viscosity of 1-octanol slowed down its transport.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Chukwunonso Anyaoku, Sati Bhattacharya, Rajarathinam Parthasarathy
Summary: This study aimed to enhance understanding of settling dynamics in viscoelastic fluids by developing a semi-empirical correlation and a dimensionless ratio, which accurately described the characteristics of settling suspensions.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Antti I. Koponen, Janika Viitala, Atsushi Tanaka, Baranivignesh Prakash, Olli-Ville Laukkanen, Ari Jasberg
Summary: This study focuses on the development of foam application chemicals for the paper and board industry. The research explores the rheology of the polyvinyl alcohol foam used in the process. Measurements were conducted to determine the foam viscosity and slip flow. The results suggest that slip flow contributes significantly to the total flow rate, and the obtained viscosity and slip models provide a solid foundation for industrial processes.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Dalei Sun, Jinghui Cai, Yating Yang, Zhiwu Liang
Summary: In this study, Fe-doped alpha-Bi2O3 catalysts with different Fe/Bi molar ratios were synthesized and utilized in the carbonylation of isobutyl amine with CO2. The results showed that Fe doping significantly enhanced the catalytic abilities of alpha-Bi2O3.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Yuan Tian, Xinxin Wang, Yanrong Liu, Wenping Hu
Summary: This paper predicts the solubility of nitrogen gas in ionic liquids (ILs) using two quantitative structure-property relationship (QSPR) models. By combining machine learning methods and ionic fragments contribution method, the accuracy and reliability of the prediction models are improved.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Liwang Wang, Wei Liu, Pan Yang, Yulong Chang, Xiaoxu Duan, Lingyu Xiao, Yaoming Hu, Jiwei Wu, Liang Ma, Hualin Wang
Summary: This study investigates the effective phase interfacial area (ae) of hydro-jet cyclones at different injection angles. The results show that a 45 degrees upward incidence angle yields the most favorable flow field characteristics for efficient mass transfer. The significant enhancement in ae of the hydro-jet cyclones offers the advantage of reducing equipment volume and cost savings.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Chuanjun Wu, Jiangzhi Chen, Jiyue Sun, I-Ming Chou, Shenghua Mei, Juezhi Lin, Lei Jiang
Summary: In this study, the solubility of H2S hydrate in water was measured using Raman spectroscopy. The results showed that the solubility increases with temperature under certain equilibrium conditions, and the solubility also depends on pressure and temperature under different equilibrium conditions. A thermodynamic model based on the van der Waals-Platteeuw theory was developed to predict the solubility, demonstrating its accuracy.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Lorenzo Brivio, Serena Meini, Mattia Sponchioni, Davide Moscatelli
Summary: This study investigates the influence of three main parameters and proposes a kinetic model to predict the optimal operating conditions for high yield of dimethyl terephthalate (DMT) in the chemical recycling process of polyethylene terephthalate (PET).
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Hongju Lin, Fanhui Liao, Yanchang Chu, Mingyu Xie, Lun Pan, Yuanyuan Wang, Lijian Leng, Donghai Xu, Le Yang, Gangfeng Ouyang
Summary: A honeycomb NiCo/C-Na catalyst with a micro-meso-macroporous structure has been fabricated and shown to have significantly higher catalytic activity for the decarboxylation of fatty acids. It also proves to be efficient in upgrading sludge HTL bio-crude, resulting in a biofuel with decreased viscosity and increased density.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Xiaoxian Li, Rui Li, Min Lin, Mingde Yang, Yulong Wu
Summary: A series of coated non-noble metal porous carbon catalysts were synthesized and applied to the aqueous-phase deoxygenation of algal bio-oil. One of the catalysts showed excellent deoxygenation selectivity and catalytic activity at 250 degrees C. The catalyst exhibited good hydrothermal stability and the reaction mechanism was proposed based on product analysis and active site analysis.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
M. V. Chudakova, M. V. Popov, P. A. Korovchenko, E. O. Pentsak, A. R. Latypova, P. B. Kurmashov, A. A. Pimenov, E. A. Tsilimbaeva, I. S. Levin, A. G. Bannov, A. V. Kleymenov
Summary: A series of catalysts with different potassium contents were prepared using solution combustion synthesis and characterized using various techniques. The results showed that the potassium content affected the phase composition and texture of the catalysts. The addition of a small amount of potassium resulted in a change in particle size distribution, leading to higher hydrogen yield. The Ni-1%K2O/Al2O3 catalyst exhibited the highest hydrogen yield at temperatures of 675 and 750 degrees Celsius.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Aliakbar Roosta, Nima Rezaei
Summary: In this study, we modified the electrolyte cubic plus association equation of state (e-CPA EoS) and integrated it with two electrical conductivity models to estimate the electrical conductivity of 11 monovalent electrolyte solutions in water. The modified e-CPA model demonstrated better performance and the hybridization with electrical conductivity models resulted in two predictive models for estimating the electrical conduction of dilute and concentrated electrolyte solutions. These predictive models showed relative average percentage deviations (AARD) of 11.15% and 13.87% over wide ranges of temperature and electrolyte concentration.
CHEMICAL ENGINEERING SCIENCE
(2024)
Article
Engineering, Chemical
Haoren Niu, Jianzheng Wang, Qingzhu Jia, Qiang Wang, Jin Zhao, Fangyou Yan
Summary: A study developed two quantitative structure-property relationship models for the complexation performance of alpha- and beta-cyclodextrins and validated their stability and predictive ability through internal and external validation. The models showed robustness and satisfactory performance, as demonstrated by the experimental results and model validations. These models can effectively predict the binding constants between cyclodextrins and various types of molecules, providing valuable tools for cyclodextrin design.
CHEMICAL ENGINEERING SCIENCE
(2024)
