Activity-based diubiquitin probes for elucidating the linkage specificity of deubiquitinating enzymes

OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis

(2013) Tycho E.T. Mevissen et al.   CELL

OTULIN Antagonizes LUBAC Signaling by Specifically Hydrolyzing Met1-Linked Polyubiquitin

(2013) Kirstin Keusekotten et al.   CELL

On Terminal Alkynes That Can React with Active-Site Cysteine Nucleophiles in Proteases

(2013) Reggy Ekkebus et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Profiling Ubiquitin Linkage Specificities of Deubiquitinating Enzymes with Branched Ubiquitin Isopeptide Probes

(2012) Alexander Iphöfer et al.   CHEMBIOCHEM

Ubiquitin-Based Probes Prepared by Total Synthesis To Profile the Activity of Deubiquitinating Enzymes

(2012) Annemieke de Jong et al.   CHEMBIOCHEM

Fluorescence-based active site probes for profiling deubiquitinating enzymes

(2012) Joanna F. McGouran et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Chemical Synthesis of Ubiquitinated Peptides with Varying Lengths and Types of Ubiquitin Chains to Explore the Activity of Deubiquitinases

(2011) Sudhir N. Bavikar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Activity-Based Chemical Proteomics Accelerates Inhibitor Development for Deubiquitylating Enzymes

(2011) Mikael Altun et al.   CHEMISTRY & BIOLOGY

The Differential Modulation of USP Activity by Internal Regulatory Domains, Interactors and Eight Ubiquitin Chain Types

(2011) Alex C. Faesen et al.   CHEMISTRY & BIOLOGY

Nonhydrolyzable Ubiquitin−Isopeptide Isosteres as Deubiquitinating Enzyme Probes.

(2010) Anitha Shanmugham et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Chemically ubiquitylated PCNA as a probe for eukaryotic translesion DNA synthesis

(2010) Junjun Chen et al.   Nature Chemical Biology

Engineered diubiquitin synthesis reveals Lys29-isopeptide specificity of an OTU deubiquitinase

(2010) Satpal Virdee et al.   Nature Chemical Biology

Ubiquitin C-Terminal Electrophiles Are Activity-Based Probes for Identification and Mechanistic Study of Ubiquitin Conjugating Machinery

(2009) Kerry Routenberg Love et al.   ACS Chemical Biology

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Evidence for Bidentate Substrate Binding as the Basis for the K48 Linkage Specificity of Otubain 1

(2009) Tao Wang et al.   JOURNAL OF MOLECULAR BIOLOGY

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activity-Based Protein Profiling: From Enzyme Chemistry to Proteomic Chemistry

(2008) Benjamin F. Cravatt et al.   Annual Review of Biochemistry

Structural basis and specificity of human otubain 1-mediated deubiquitination

(2008) Mariola J. Edelmann et al.   BIOCHEMICAL JOURNAL

Structural basis for specific cleavage of Lys 63-linked polyubiquitin chains

(2008) Yusuke Sato et al.   NATURE