Article
Spectroscopy
Hang Su, Jingpei Wang, Xiuxiu Yue, Benhua Wang, Xiangzhi Song
Summary: A ratiometric fluorescent probe MA-N2H4 was developed for simple and convenient detection of hydrazine (N2H4) in environmental and biological systems. The probe exhibited a significant blue-shifted emission and a rapid increase in fluorescent intensity ratio after treatment with N2H4, allowing for fast detection. Additionally, the probe was successfully used for tracking N2H4 in living cells and zebrafish.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yabing Gan, Guoxing Yin, Xiaming Zhang, Li Zhou, Yibao Zhang, Haitao Li, Peng Yin
Summary: A novel fluorescent probe HN-ClO was developed for monitoring HOCl, showing good water-solubility, photostability, fluorescence quantum yield, and large Stokes shift with excellent selectivity and high sensitivity. This probe not only performed well in vitro but also successfully monitored endogenous and exogenous HOCl in living cells, zebrafishes, and mice, providing potential for further exploration of the physiological and pathological roles of hypochlorous acid in biological systems.
Article
Optics
Jingpei Wang, Fan Zhang, Liu Yang, Benhua Wang, Xiangzhi Song
Summary: Cysteine, homocysteine, and glutathione are important biothiol species involved in physiological activities, with abnormal levels linked to various diseases. The novel fluorescent probe JSC-RSH shows high sensitivity and selectivity towards biothiols, with low cytotoxicity when used for monitoring endogenous and exogenous biothiols in cells.
JOURNAL OF LUMINESCENCE
(2021)
Article
Chemistry, Physical
Wenqin Yao, Dongjian Zhu, Yun Ye, Biao Wang, Wei Xie, Aishan Ren
Summary: A novel colorimetric and ratiometric fluorescent probe 1 was designed and synthesized for the detection of Cu2+. Probe 1 exhibited maximum absorption and fluorescence emission peaks at 385 nm and 495 nm, respectively, with a large Stokes shift of 110 nm. In the presence of Cu2+, a bathochromic shift to 415 nm and 560 nm was observed in the absorption and fluorescence emission peaks, respectively, due to the Cu2+-induced hydrolysis reaction. The probe showed a significant change in the fluorescence intensity ratio (F560 nm/F495 nm), with high sensitivity, fast response time, and excellent selectivity for Cu2+ over other metal ions in aqueous solution.
JOURNAL OF MOLECULAR STRUCTURE
(2023)
Article
Spectroscopy
Xiaoxia Chen, Wenjuan Cai, Gang Liu, Yayi Tu, Congbin Fan, Shouzhi Pu
Summary: In this study, a new europium complex fluorescent probe Eu(tdl)2abp was successfully synthesized for efficient and specific recognition of hydrogen sulfide (H2S). The probe exhibited on-off fluorescence signals for H2S and its color changes could be observed with naked eyes. Eu(tdl)2abp showed a short response time, high selectivity, good anti-interference, and a large Stokes shift. The probe demonstrated a linear relationship between relative fluorescence intensity and H2S concentration with a low detection limit. The mechanism of H2S detection using Eu(tdl)2abp was characterized and the probe was successfully applied in the detection of H2S in natural water and living cells.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Yuka Muraoka, Junya Muramoto, Yu Yasuhara, Mayuko Kawatake, Takashi Sakamoto
Summary: In this study, an NIR fluorescence switch-on probe for G4 imaging with higher selectivity and large Stokes shift was developed. This probe may contribute significantly to understanding the behaviors of G4 nucleic acids in cells and biological tissues.
ANALYTICAL CHEMISTRY
(2023)
Article
Spectroscopy
Jie Zhang, Xibin Zhou, Jun Wang, Dawei Fang
Summary: A novel luminescent complex with red color was synthesized for sequential detection of Cu2+ and biothiols. The sensing system showed good selectivity, high sensitivity, and a large Stokes shift.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Multidisciplinary
Lifang Guo, Xin Jin, Hao Liu, Jiangnan Zhu, Zhiyun Zhang, Jianhua Su
Summary: In this study, a novel concept of constructing a cassette based on Vibration-Induced Emission (VIE) and Förster Resonance Energy Transfer (FRET) was introduced. By utilizing a VIE donor with dual emission bands and linking it with a acceptor like Cy5, a high-resolution dual-color fluorescent imaging platform was developed. The VIE-FRET technology showed excellent spectral difference and ultra-large pseudo-Stokes shift, allowing clear and intuitive visualization of different viscosity regions in vivo.
SCIENCE CHINA-CHEMISTRY
(2021)
Article
Spectroscopy
Yu Liu, Bing Jiang, Linlin Zhao, Li Zhao, Qiyu Wang, Ce Wang, Baocai Xu
Summary: The fluorescent probe D-GT shows excellent detection performance towards Cu2+ in aqueous solutions, displaying sensitivity and versatility in real environments. The 1:1 coordinate stoichiometry and high association constant with Cu2+ make it a promising tool for detecting copper ions.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Spectroscopy
Tian-Zhen Liu, Yu-Chang Yuan, Bao-Xiang Zhao
Summary: A novel fluorescence resonance energy transfer (FRET)-based ratiometric emission fluorescent probe AT was developed for the detection of SO32-/HSO3-. It showed high energy transfer efficiency, large pseudo-Stokes shift, good selectivity and quick response. The probe also demonstrated its applicability in real samples such as environmental water and sugar.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Juan Liu, Zhi-Qing Wang, Guo-Jiang Mao, Wen-Li Jiang, Min Tan, Fen Xu, Chun-Yan Li
Summary: A near-infrared fluorescent probe named IX has been designed and synthesized for detecting Cysteine (Cys) with high sensitivity and selectivity. The fluorescence enhancement mechanism involves the reaction of IX with Cys to release IX-OH, allowing for imaging of Cys in cells and tumor mice.
ANALYTICA CHIMICA ACTA
(2021)
Article
Chemistry, Organic
Zinaida M. Kaskova, Nadezhda S. Baleeva, Yulia V. Nelyubina, Anastasia A. Andrianova, Zinaida M. Kaskova, Aleksandra S. Tsarkova
Summary: A novel highly fluorescent benzothiophene-based dye with five fused rings was synthesized using a simple two-step method, showing a large Stokes shift in ethanol. The structural features of the compound allow for easy functionalization of the carbon core, potentially leading to the development of new classes of fluorescent dyes.
Article
Spectroscopy
Minghui Wang, Jiajia Chen, Xin Gu, Xindi Yang, Jia Fu, Kuoxi Xu
Summary: In this study, a novel near-infrared emitting fluorescent probe WFP-PC was developed for the detection of hydrogen sulfide (H2S). The probe showed significant fluorescence enhancement and a response time within 4 minutes upon treatment with H2S, with a detection limit as low as 0.47 μM. It was successfully applied for imaging exogenous/endogenous H2S in cells and mice, indicating its potential as a molecular tool for H2S detection in living systems.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Spectroscopy
Rui Guo, Qing Liu, Yonghe Tang, Shushun Cai, Xiaoya Li, Xi Gong, Yingjie Yang, Weiying Lin
Summary: Small molecule biological thiols play crucial roles in maintaining cellular activities and abnormal levels are associated with diseases. A new fluorescent probe Ty-Cys1 was designed in this study for effective monitoring of Cys changes.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Rong Tang, Chao Wang, Xuan Zhou, Mengxiang Feng, Zefei Li, Yihan Wang, Guang Chen
Summary: The homeostasis of biothiols is crucial for organisms' health. A fluorescent probe (7HIN-D) based on a chalcone fluorophore 7HIN was developed for intracellular biothiols detection. The probe exhibited turn-on AIE fluorescence upon the nucleophilic substitution reaction between biothiols and DNBS unit, with good sensitivity and selectivity. It successfully detected endogenous biothiols in living cells due to its excellent performance, biocompatibility, and low cytotoxicity.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Multidisciplinary
Ethan J. Miller, Kislon Voitchovsky, Margarita Staykova
Article
Chemistry, Multidisciplinary
Kevin N. Baumann, Luca Piantanida, Javier Garcia-Nafria, Diana Sobota, Kislon Voitchovsky, Tuomas P. J. Knowles, Silvia Hernandez-Ainsa
Article
Chemistry, Multidisciplinary
Sarah J. Goodband, Steven Armstrong, Halim Kusumaatmaja, Kislon Voitchovsky
Article
Biochemical Research Methods
Emanuela Torelli, Jerzy Kozyra, Ben Shirt-Ediss, Luca Piantanida, Kislon Voitchovsky, Natalio Krasnogor
ACS SYNTHETIC BIOLOGY
(2020)
Article
Physics, Applied
Luca Piantanida, Amir F. Payam, Jing Zhong, Kislon Voitchovsky
PHYSICAL REVIEW APPLIED
(2020)
Article
Multidisciplinary Sciences
Clodomiro Cafolla, William Foster, Kislon Voitchovsky
Article
Chemistry, Physical
Borys Snopok, Arwa Laroussi, Clodomiro Cafolla, Kislon Voitchovsky, Tetyana Snopok, Vladimir M. Mirsky
Summary: This study investigated the cleaning and polishing of polycrystalline gold films for surface functionalization by wet chemical etching in hydrochloric acid and hydrogen peroxide solutions. The optimized surfaces showed reduced roughness, removed contaminants, increased hydrophilicity and modified the gold surface. This method offers a simple, reliable and rapid technique for preparing gold surfaces for further functionalization in chemical and biochemical sensing applications.
SURFACES AND INTERFACES
(2021)
Article
Instruments & Instrumentation
Amir F. Payam, Luca Piantanida, Kislon Voitchovsky
Summary: Scanning probe microscopies rely on nanoscale probe positioning for local information; AFM uses vertical oscillation for accuracy; high-speed scanner designed for directional lateral vibrations in measurement.
REVIEW OF SCIENTIFIC INSTRUMENTS
(2021)
Article
Nanoscience & Nanotechnology
Sarah J. Goodband, Halim Kusumaatmaja, Kislon Voitchovsky
Summary: Capillary liquid bridges are widely present in nature and industrial processes. Quantitative measurements of their behavior on smart surfaces, such as liquid infused surfaces, are challenging due to weak contact line pinning and contact angle hysteresis. In this study, a relatively inexpensive setup capable of measuring capillary forces with sensitivity in the micronewton range and quantifying the bridge's geometry was developed. A new analysis software was also introduced to minimize errors and noise in retrieving the relevant geometrical parameters of the bridge from optical observations.
Article
Chemistry, Multidisciplinary
Rashad Kariuki, Rowan Penman, Saffron J. Bryant, Rebecca Orrell-Trigg, Nastaran Meftahi, Russell J. Crawford, Chris F. McConville, Gary Bryant, Kislon Voitchovsky, Charlotte E. Conn, Andrew J. Christofferson, Aaron Elbourne
Summary: Nanomaterials have the potential to revolutionize biological and biomedical research, and this study provides detailed insights into how gold nanoparticles interact with phospholipid membranes. The study shows that the nanoparticles can be absorbed and internalized by fluid-phase membranes, and partially embed into gel-phase membranes, causing perturbations throughout the bilayers.
Article
Multidisciplinary Sciences
Benjamin A. Legg, Kislon Voitchovsky, James J. De Yoreo
Summary: In this study, the growth process of an aluminum hydroxide film from an aqueous solution was directly observed using high-speed atomic force microscopy. The results showed that the dynamically fluctuating nanostructures preceding the formation of the film exhibited similar characteristics to those predicted by classical nucleation theory. However, the cluster energy landscape deviated from classical expectations. Kinetic Monte Carlo simulations revealed that these deviations were caused by electrostatic interactions between the clusters and the underlying substrate, resulting in microphase separation and the formation of a nanostructured surface phase.
Article
Nanoscience & Nanotechnology
Clodomiro Cafolla, Kislon Voitchovsky, Amir Farokh Payam
Summary: This article introduces a non-invasive method using atomic force microscopy (AFM) to quantify the local mechanical and dispersion properties of a sample with nanometer precision. The method accurately determines the Hamaker constant and effective Young's modulus at a specific location on the sample, and has been validated on various materials and thin films.
Article
Chemistry, Multidisciplinary
Clodomiro Cafolla, Kislon Voitchovsky
Article
Chemistry, Multidisciplinary
William Foster, Keisuke Miyazawa, Takeshi Fukuma, Halim Kusumaatmaja, Kislon Voitchovsky
Article
Chemistry, Multidisciplinary
William Trewby, Jordi Faraudo, Kislon Voitchovsky
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
