Continuous synthesis of artemisinin-derived medicines

Flow Synthesis of Substituted γ-Lactones by Consecutive Photocatalytic/Reductive Reactions

(2014) Maurizio Fagnoni et al.   ADVANCED SYNTHESIS & CATALYSIS

Development of a Multi-Step Synthesis and Workup Sequence for an Integrated, Continuous Manufacturing Process of a Pharmaceutical

(2014) Patrick L. Heider et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Multiple Organolithium Generation in the Continuous Flow Synthesis of Amitriptyline

(2013) Lukas Kupracz et al.   ADVANCED SYNTHESIS & CATALYSIS

Heating under High-Frequency Inductive Conditions: Application to the Continuous Synthesis of the Neurolepticum Olanzapine (Zyprexa)

(2013) Jan Hartwig et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

End-to-End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation

(2013) Salvatore Mascia et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Flash chemistry: flow chemistry that cannot be done in batch

(2013) Jun-ichi Yoshida et al.   CHEMICAL COMMUNICATIONS

Flow chemistry syntheses of natural products

(2013) Julio C. Pastre et al.   CHEMICAL SOCIETY REVIEWS

A Continuous-Flow Process for the Synthesis of Artemisinin

(2013) Daniel Kopetzki et al.   CHEMISTRY-A EUROPEAN JOURNAL

Multistep synthesis of amides from alcohols and amines in continuous flow microreactor systems using oxygen and urea hydrogen peroxide as oxidants

(2013) Xiaoying Liu et al.   GREEN CHEMISTRY

End-to-end continuous flow synthesis and purification of diphenhydramine hydrochloride featuring atom economy, in-line separation, and flow of molten ammonium salts

(2013) David R. Snead et al.   Chemical Science

Continuous-Flow Synthesis of the Anti-Malaria Drug Artemisinin

(2012) François Lévesque et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The global pipeline of new medicines for the control and elimination of malaria

(2012) Melinda P Anthony et al.   MALARIA JOURNAL

An expeditious synthesis of imatinib and analogues utilising flow chemistry methods

(2012) Mark D. Hopkin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Streamlined Process for the Conversion of Artemisinin to Artemether

(2012) Rodger W. Stringham et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Facile Stoichiometric Reductions in Flow: An Example of Artemisinin

(2012) Xiaolei Fan et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A Scalable Two-Step Continuous Flow Synthesis of Nabumetone and Related 4-Aryl-2-butanones

(2011) Monica Viviano et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Continuous Preparation of Arylmagnesium Reagents in Flow with Inline IR Monitoring

(2011) Tobias Brodmann et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

A flow-based synthesis of Imatinib: the API of Gleevec

(2010) Mark D. Hopkin et al.   CHEMICAL COMMUNICATIONS

Demand for malaria drug soars

(2010) Richard Van Noorden   NATURE

KMnO4-Mediated Oxidation as a Continuous Flow Process

(2010) Jörg Sedelmeier et al.   ORGANIC LETTERS

Palladium-catalyzed amination reactions in flow: overcoming the challenges of clogging via acoustic irradiation

(2010) Timothy Noël et al.   Chemical Science

The Continuous-Flow Synthesis of Ibuprofen

(2009) Andrew R. Bogdan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Looking Forward in Pharmaceutical Process Chemistry

(2009) I. W. Davies et al.   SCIENCE