Article
Chemistry, Analytical
Shaoheng Li, Shi Feng, Xuerong Song, Qingchuan Zheng, Guodong Feng, Zhiguang Song
Summary: Biological thiols, including cysteine, homocysteine, and glutathione, play important roles in physiological and pathological processes. Abnormal concentration of these thiols can lead to various diseases. In this study, a series of fluorescent molecules based on benzotriazole and coumarin were designed and synthesized. The molecule BTAC(e) showed high selectivity towards homocysteine and could react with it to enhance fluorescence. The probe also exhibited excellent selectivity towards homocysteine compared to cysteine and glutathione. The fluorescence intensity had a linear relationship with the concentration of homocysteine and the probe could be used for imaging homocysteine in living cells.
MICROCHEMICAL JOURNAL
(2023)
Article
Spectroscopy
Lei Hu, Xi Chen, Kun Yu, Na Huang, Hailing Du, Yan Wei, Yunjun Wu, Hui Wang
Summary: Visualizing endogenous histidine in living systems is important and challenging work. Two weak-emission iridium(III) complexes (IrL1 and IrL2) were designed and synthesized, with IrL2 showing better performance for detecting histidine. The recognition mechanism involves histidine substituting solvent ligands, and IrL2 can be used to visualize endogenous histidine in living cells.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Optics
Xiaodan Zeng, Jie Chen, Shihua Yu, Zhigang Liu, Mingshuo Ma
Summary: A turn-on fluorescent probe based on N-oxide was designed and synthesized to detect Fe2+ in living systems. The probe displayed excellent sensitivity and low interference, and was successfully used for monitoring Fe2+ in living cells and water samples.
JOURNAL OF LUMINESCENCE
(2022)
Review
Chemistry, Inorganic & Nuclear
Wei Quan, Wenhui Song, Qian Zhang, Huawei Huang, Weiying Lin
Summary: The liver, as the metabolic and detoxification center, plays a vital role in various physiological processes. Normal liver function is crucial for maintaining overall health, while abnormal liver function can lead to liver diseases. Early diagnosis of liver diseases is essential for timely treatment. The use of fluorescent probes for detecting biomarkers of liver diseases has provided valuable insights for pathological studies, drug development, and disease diagnosis and treatment in recent years. This review summarizes the progress of fluorescence probes in detecting hepatopathy-related biomarkers and discusses the current challenges and future directions. The development of long wavelength probes, multi-detection probes, quantitative analysis probes, and multi-modal probes is expected to be a popular trend. This review aims to facilitate the development of novel fluorescent probes for disease detection and provide guidance for diagnosis and treatment.
COORDINATION CHEMISTRY REVIEWS
(2023)
Review
Chemistry, Inorganic & Nuclear
Jingting Zhan, Wenhui Song, Enxiang Ge, Lixuan Dai, Weiying Lin
Summary: Reversible fluorescent probes have been widely used in biological research due to their ability to observe dynamic changes of biomolecules in real-time. This review categorizes reversible fluorescent probes into six groups based on the principles of reversible reactions and focuses on their interactions with physiological compounds and small molecule compounds or microenvironments. Representative examples of reversible processes, including complex reactions, addition reactions, redox reactions, and spiral cyclization, are reviewed to demonstrate the potential of reversible fluorescent probes for visualizing intracellular dynamic changes. Furthermore, the challenges and future directions of utilizing reversible fluorescent probes in biological applications are discussed.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Chemistry, Multidisciplinary
Xiao-Lu Wang, Jia-Yue Tian, Xuan-Chen Guo, Fu-Qiang Zhang, Linfeng Liang, Xian-Ming Zhang
Summary: DMSO residue on chemical products is difficult to determine quickly, but the Cd-II metal-organic framework SXU-4 can detect trace amounts of DMSO and serve as a luminescent probe for purity detection. Fluorescence experiments and computational results reveal the enhanced DMSO-MOF conjugation effect.
CHEMISTRY-A EUROPEAN JOURNAL
(2021)
Review
Chemistry, Inorganic & Nuclear
Deming He, Lishen Zhang, Yuanqiang Sun
Summary: Pyronine dyes have gained considerable attention as powerful fluorescence imaging tools due to their tunable photo physical properties. By modifying the Pyronine platform, versatile fluorescent probes with diverse functionalities can be obtained, making them suitable for in vivo and in vitro bioimaging.
COORDINATION CHEMISTRY REVIEWS
(2022)
Review
Chemistry, Multidisciplinary
Hejin Jiang, Zhenping Cao, Ying Liu, Rui Liu, Yan Zhou, Jinyao Liu
Summary: This review discusses the strategies for preparing bacteria-based living probes, including biological engineering, chemical modification, intracellular loading, and optical manipulation. It summarizes the recent progress of these probes in different imaging modalities and highlights their applications in bioimaging and diagnosis of bacterial infections, cancers, and intestine-associated diseases. The advantages, challenges, and future perspectives of bacteria-based living probes are also discussed.
Review
Medicine, Research & Experimental
Xiaoning Zhang, Shasha Li, Huizhen Ma, Hao Wang, Ruiping Zhang, Xiao-Dong Zhang
Summary: NIR-II imaging technology has made significant progress in diagnosing diseases with its high resolution and deep tissue penetration capabilities. Activatable NIR-II fluorescence probes show great potential in reporting pathological changes, exhibiting tunable properties and excellent biocompatibility.
Review
Chemistry, Inorganic & Nuclear
Lei Feng, Jing Ning, Xiangge Tian, Chao Wang, Zhenlong Yu, Xiaokui Huo, Tian Xie, Baojing Zhang, Tony D. James, Xiaochi Ma
Summary: Cytochrome P450 (CYP) enzymes are haem-containing proteins mainly involved in the oxidative metabolism of various chemicals. Fluorescent probes are useful molecular tools for selectively detecting CYP activity, facilitating important insights into the activity expression of CYP enzymes.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Biochemistry & Molecular Biology
Yuan-Xiang Li, Dong-Tai Xie, Ya-Xi Yang, Zhao Chen, Wu-Yingzheng Guo, Wen-Chao Yang
Summary: Enzymes, as biological catalysts, play a vital role in controlling metabolic reactions. The regulation and amount of enzymes in living cells are indicators of the cell's metabolic status. Small-molecule fluorescent probes are of interest due to their high sensitivity, selectivity, and potential for automated detection. However, designing an ideal fluorescent probe for versatile purposes is challenging. In the future, the focus will be on improving the selectivity, sensitivity, and penetration ability of enzyme-targeting fluorescent probes, as well as coupling them with other imaging molecules/technologies.
Review
Multidisciplinary Sciences
Weiguo Qiao, Zhong'an Li
Summary: This review summarizes the recent progress of SQ-based fluorescent materials and their biomedical applications. The synthetic routes and design principles of SQ-based fluorescent materials, as well as their aggregation-induced luminescence behaviors, are discussed. The biomedical applications of SQ-based fluorescent materials in cell imaging, fluorescent sensors, and therapeutic agents are introduced.
Article
Chemistry, Analytical
Xin Wang, Caiyun Liu, Hanchuang Zhu, Siyu Cheng, Yan Zhang, Meijun Su, Xiaodi Rong, Miaohui Yu, Wenlong Sheng, Baocun Zhu
Summary: Nickel, widely used in industrial production and distributed in human body, can cause harm when present in excessive amounts. The development of sensitive detection methods for nickel ions has attracted attention, with the reactive fluorescent probe FA-Ni achieving highly selective and ultra-sensitive recognition of nickel ions. The probe can be applied for environmental detection and in-situ imaging in living cells, providing a powerful tool for related disease diagnosis and understanding of nickel ions' physiological function.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Article
Spectroscopy
Xiao-Lei Xue, Yang Wang, Hao Zhang, Shaojin Chen, Shu-Yan Niu, Lingyun Cui, Kun-Peng Wang, Zhi-Qiang Hu
Summary: Biothiols such as cysteine, homocysteine, and glutathione, which are important in life activities, have been the subject of recent research on their quantitative tracking and analysis in living organisms. A fluorescent probe called COUN was designed and synthesized for the color recognition of cysteine, homocysteine, and glutathione. The probe specifically recognized homocysteine, showing significant fluorescence enhancement. Moreover, the probe showed good linear relationships with different concentrations of cysteine, homocysteine, and glutathione.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Review
Nanoscience & Nanotechnology
Ragini Singh, Santosh Kumar, Santanu Bera, Susanta Kumar Bhunia
Summary: MXene quantum dots are excellent zero-dimensional nanomaterials with outstanding photophysical and chemical properties, making them ideal candidates for environmental and biomedical applications. This review paper provides an in-depth analysis of the synthesis of MXene quantum dots, their sensing capabilities towards various analytes, and their bioimaging applications. Challenges and perspectives are also discussed.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Environmental
Lijia Wan, Yingqi Tang, Lei Chen, Kai Wang, Jiaqi Zhang, Yang Gao, Jin Yong Lee, Ting Lu, Xingtao Xu, Jiabao Li, Yonghui Zheng, Likun Pan
Summary: A new synthesis strategy for the fabrication of a g-C3N4/Mo2CTx hybrid was developed in this study, enhancing the performance of Mo2CTx and providing a new pathway for lithium storage. The hybrid exhibited significantly higher Coulombic efficiency and superior lithium storage performance compared to pure Mo2CTx.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Physical
Yingqi Tang, Wenbo Huai, Hao Li, Xiaotong Mao, Ju Xie, Jin Yong Lee, Aiping Fu
Summary: Density functional theory calculations were used to study the adsorption behavior of ionic liquids on 15th group nanosheets, revealing that ILs can interact with nanosheets through non-covalent interactions and have a small impact on the electronic properties. The research findings could provide insights into the potential applications of ILs in functionalizing nanosheets.
INTERNATIONAL JOURNAL OF QUANTUM CHEMISTRY
(2021)
Article
Chemistry, Physical
Heng Zhang, Jin Yong Lee, Hongguang Liu
Summary: Customizing graphene with specific structural or foreign-atom defects can lower the energy barrier for O-3 decomposition, leading to its sustainable conversion to O-2. Nitrogen-doped graphene shows excellent adsorption selectivity and separation of O-3, making it a promising catalyst for O-3 decomposition.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Nanoscience & Nanotechnology
Mahesh Datt Bhatt, Jin Yong Lee
Summary: This paper investigates the properties of monoclinic scheelite bismuth vanadate in water splitting using DFT + U calculations. The results show that the (001) surface of BiVO4 is more stable in vacuum, while the (110) surface is more stable in water and under strain in vacuum. This provides important insights into the role of different facets on the BiVO4 surface for photocatalytic reactions.
Article
Chemistry, Physical
Xiaotong Han, Nannan Li, Ying Bo Kang, Qingyun Dou, Peixun Xiong, Qing Liu, Jin Yong Lee, Liming Dai, Ho Seok Park
Summary: ReS2 and NiFe-LDH heteronanosheets have unique trifunctional active sites for efficient conversion in Zn-air battery/electrolyzer systems. The coupling effect between S-O bonds and NiFe-LDH with ReS2, along with a well understood mechanism, enable high efficiency and potential in electricity storage and H-2 production.
ACS ENERGY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Hao Li, Abbas Salimi, Francis Kirby B. Burnea, Hu Shi, Jin Yong Lee
Summary: This study investigates the structural properties of A beta 40 heterodimers under the influence of histidine, revealing different aggregation trends in different heterodimers, with (epsilon epsilon epsilon : delta delta delta) dimers more easily aggregating into fibrils. This research contributes to understanding the tautomeric effect on A beta heterodimers and potential implications for the pathogenesis of Alzheimer's disease.
BULLETIN OF THE KOREAN CHEMICAL SOCIETY
(2021)
Article
Chemistry, Multidisciplinary
Hong-Bo Cheng, Hao Dai, Xiaoqiong Tan, Hao Li, Huihui Liang, Chenyan Hu, Mingwei Huang, Jin Yong Lee, Jing Zhao, Liming Zhou, Yuguang Wang, Liqun Zhang, Juyoung Yoon
Summary: This article introduces a novel supramolecular theranostic system that combines biomarker protein activation and a host-guest strategy. The authors demonstrate the design of a nanoparticulate theranostic agent that can detect albumin and treat cancer. The system also exhibits enhanced biocompatibility and photothermal conversion efficiency, making it a promising strategy for photodynamic and photothermal immunotherapy.
ADVANCED MATERIALS
(2022)
Article
Engineering, Environmental
Yipin Lv, Baotao Kang, Yuan Yuan, Guozhu Chen, Jin Yong Lee
Summary: This study demonstrates that gamma GyNRs can serve as excellent bifunctional electrocatalysts after functionalization, with the binding strength of H atom acting as a general descriptor for designing bifunctional electrocatalysts. By incorporating scaling relationship analysis and a machine learning algorithm, deeper insights into the reaction mechanisms were gained, providing valuable information for the rational design of novel CMFCs.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Engineering, Environmental
Baotao Kang, Yuan Yuan, Yipin Lv, Hongqi Ai, Jin Yong Lee
Summary: This study focuses on developing efficient and low-cost electrocatalysts for the nitrogen reduction reaction (NRR) under ambient conditions. By doping gamma-graphyne with B, N, O, P, and S, the researchers identified a specific configuration that exhibited excellent NRR activity. The findings provide insight into improving NRR activity and offer a new strategy for developing metal-free catalysts for this reaction.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Abbas Salimi, Sompriya Chatterjee, Jin Yong Lee
Summary: Clinical research suggests that Type 2 diabetes (T2D) may be a risk factor for Alzheimer's disease (AD) development, possibly due to the improper aggregation of Amyloid-beta (Aβ) in both diseases. This computational research reveals the cross-seeding between Amylin1-37 and Aβ 40, shedding light on the pathological link between AD and T2D.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Jinze Li, Hao Li, Wenfu Xie, Shijin Li, Yuke Song, Kui Fan, Jin Yong Lee, Mingfei Shao
Summary: The study introduced a fast and simple flame-assisted strategy to construct oxygen-coordinated single-atom catalysts on integrated carbon nanotube arrays, showing promising performance in electrocatalysis. Through density functional theory calculations, it was demonstrated that oxygen in the carbon substrate provides homogeneous sites for efficient anchoring of metal atoms, resulting in optimized activities of the single-atom catalysts.
Article
Engineering, Multidisciplinary
Xiaotong Han, Nannan Li, Peixun Xiong, Yingbo Kang, Qingyun Dou, Qing Liu, Wenwu Li, Jin Yong Lee, Ho Seok Park
Summary: In this study, a free-standing trifunctional and durable electrocatalyst was developed, achieving high activities and efficiencies in water electrolysis and rechargeable Zn-air batteries.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Chemistry, Physical
Yuan Yuan, Xiaoxue Song, Baotao Kang, Jin Yong Lee
Summary: This article reports a novel 2D carbon nitride, C6N3, and investigates its performance as a single-atom catalyst in the electrocatalytic hydrogen evolution reaction (HER). The study reveals that C6N3 with embedded certain transition metals exhibits excellent stability, binding strength, and electrical conductivity, demonstrating its great potential in HER. Further research is needed to explore the properties and applications of C6N3 in other fields.
JOURNAL OF COLLOID AND INTERFACE SCIENCE
(2022)
Article
Chemistry, Physical
Yuan Yuan, Xiaoxue Song, Jiapeng Ma, Yanqi Chen, Fangfang Wang, Baotao Kang, Jin Yong Lee
Summary: Sodium-ion batteries (SIBs) are considered as promising alternatives to lithium-ion batteries (LIBs) due to the abundance and lower cost of sodium. This study explores the potential of alpha, beta, and gamma graphyne nanotubes as SIB anodes using density functional theory calculations. The results show that alpha graphyne nanotubes have the highest sodium storage capacity among the three types, attributed to their largest specific surface area. Furthermore, the larger pores in alpha and beta graphyne nanotubes facilitate easier diffusion and penetration of sodium atoms, indicating better rate capacity.
Article
Chemistry, Physical
Sunwoo Kang, Taekyung Kim, Jin Yong Lee
Summary: A series of Ir- and Pt-based blue phosphorescent materials were theoretically investigated using DFT calculations to improve their chemical stability in the excited state. Introducing intra- and inter-ligand interactions in Ir and Pt complexes significantly increased the Delta E((MC)-M-3-T-1) to prevent decomposition reactions, resulting in the highest reported values to date. The research provides insights into improving device lifetimes by enhancing the excited state chemical stability of deep blue phosphorescent materials.
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
(2021)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
