Article
Chemistry, Multidisciplinary
Gianluigi Albano, Gianfranco Decandia, Maria Annunziata M. Capozzi, Nicola Zappimbulso, Angela Punzi, Gianluca M. Farinola
Summary: The study found that IR irradiation-assisted solvent-free Pd-catalyzed direct C-H bond arylation of (hetero)arenes was achieved, tolerating many functional groups and making an important contribution to the development of protocols fitting with the principles of green chemistry.
Article
Chemistry, Multidisciplinary
Bo-Sheng Zhang, Ying-Hui Yang, Fan Wang, Xue-Ya Gou, Xi-Cun Wang, Yong-Min Liang, Yuke Li, Zheng-Jun Quan
Summary: This paper presents the first case of a reductive coupling reaction using indene as a reducing agent, showing a broad substrate scope and various types of reactions. The formation of an eta(3)-palladium indene intermediate was confirmed through control experiments and density functional theory calculations, while the formation of palladium anion intermediates was excluded.
CHINESE JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Multidisciplinary
Huihui Kong, Lena Viergutz, Lacheng Liu, Alexander Sandvoss, Xinchen Peng, Henning Klaasen, Harald Fuchs, Armido Studer
Summary: Aryl propiolic acids can be used as new monomers in on-surface chemistry to synthesize poly(arylenebutadiynylenes) via decarboxylative Glaser coupling. Compared to aryl alkynes, the decarboxylative coupling occurs at slightly lower temperature and with better selectivity. The activation of propiolic acids is achieved through decarboxylation, while the classical Glaser coupling involves alkyne C-H activation and shows poor selectivity. The successful polymerization of bis(propiolic acids) as monomers demonstrates the efficiency of the decarboxylative coupling. Additionally, the new activation mode is compatible with aryl bromide functionalities, allowing the formation of unsymmetric metal-organic polymers on the surface through chemoselective sequential reactions.
ADVANCED MATERIALS
(2023)
Article
Chemistry, Multidisciplinary
Xiaomin Shu, De Zhong, Yanmei Lin, Xiao Qin, Haohua Huo
Summary: We report a general and modular approach for the direct enantioselective alpha-arylation of saturated azacycles and acyclic N-alkyl benzamides via nickel/photoredox dual catalysis. This method requires no oxidants or organometallic reagents, features broad substrate scope and high enantioselectivities, and is applicable to late-stage diversification of medicinally relevant complex molecules.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Article
Chemistry, Multidisciplinary
Jingjie Yang, Zhuofan Gui, Yuli He, Shaolin Zhu
Summary: An attractive approach for selective functionalization of remote C-H bonds is the metal/hydride shift/cross-coupling reaction sequence. In this study, an unprecedented aryl-to-vinyl 1,4-nickel/hydride shift reaction is reported, which selectively traps migratory alkenylnickel species generated in situ by various coupling partners to access trisubstituted alkenes with excellent regio- and stereoselectivity. Unlike previously reported ipso-aryl coupling reactions, this strategy provides remote alkenyl C-H functionalized products with high yield and excellent chemo-, regio-, and E/Z-selectivity.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Article
Multidisciplinary Sciences
Dingyi Wang, Mingjie Li, Chengdong Shuang, Yong Liang, Yue Zhao, Minyan Wang, Zhuangzhi Shi
Summary: The authors report a method that appends arenes to arylphosphines via rhodium-catalyzed P(III)-directed ortho C-H activation, enabling one-fold, two-fold, and three-fold direct arylation of these compounds. This method provides a solution to the challenges associated with the modular preparation of biaryl monophosphines.
NATURE COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Hairong Lyu, Zuowei Xie
Summary: A unique approach to vertex-selective catalytic B-H amination has been developed, allowing the reaction to occur at either the B(3)- or B(4)-position in o-carboranes. By using different transition metal catalysts, the dehydrogenative BH/NH cross-coupling of o-carboranes and free amines has been achieved, resulting in a wide variety of B(3)- or B(4)-aminated o-carboranes with high regioselectivity.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Muhammad Asif Iqbal, Le Lu, Hina Mehmood, Ruimao Hua
Summary: This study reports a Cs2CO3-promoted cross-coupling reaction of arenes with cyano-/nitro-substituted aryl halides in DMSO to afford biaryls in the absence of ligands. The cyano/nitro groups in biaryls are shown to be useful for further transformations. Additionally, the formation of dibenzofurans from reactions between arenes and 1-bromo-2-iodobenzene is reported. A radical mechanism for the formation of biaryls is proposed based on control experiments and theoretical studies.
Article
Biochemistry & Molecular Biology
Meng-Yue Wang, Xue-Qing Zhu, Bao-Yin Zhao, Hong-Xia Zhang, Yong-Qiang Wang, Qiong Jia
Summary: In this study, the first palladium-catalyzed intramolecular C-H/C-H dehydrogenative coupling reaction of two simple arenes was reported to generate 5,6-dihydrophenanthridines. This approach has a wide substrate scope and good tolerance of functional groups, providing an efficient alternative synthesis route for important 5,6-dihydrophenanthridine compounds.
Article
Chemistry, Organic
Somraj Guha, Imran Kazi, Dhamodharan Sathish, Govindasamy Sekar
Summary: The development of direct and controlled oxidation of C(sp3)-H bonds is of great importance. A metal-free catalytic system utilizing iodine as a catalyst and dimethyl sulfoxide as an oxygen source selectively oxidizes (aryl)(heteroaryl)methanes to (aryl)(heteroaryl)methanols, providing therapeutically important derivatives in good yields.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Applied
Shen Zhao, Shimin Yang, Guopeng Du, Daopeng Zhang, Hui Liu, Feng-Gang Sun
Summary: Here, a three-component Catellani-type reaction catalyzed by the Pd/NBE/CuI cooperative system is reported. This reaction provides a convenient method for synthesizing aromatic ketones and can be performed in the presence of water. The reaction exhibits a broad substrate scope, allowing for the use of various acyl electrophiles and termination reagents.
ADVANCED SYNTHESIS & CATALYSIS
(2022)
Article
Chemistry, Inorganic & Nuclear
Fei Fan, Lixing Zhao, Meiming Luo, Xiaoming Zeng
Summary: Chemically inert C(aryl)-F bonds have been successfully cleaved and coupled with unreactive C(aryl)-O bonds using chromium catalysis, enabling high selectivity and efficiency for cross-electrophile coupling.
Article
Chemistry, Multidisciplinary
Maorui Wang, Chengqian Zhang, Chenggang Ci, Huanfeng Jiang, Pierre. H. Dixneuf, Min Zhang
Summary: Despite the challenges, we have successfully developed a room temperature approach for the direct construction of alpha-hydroxyalkyl cyclic amines through the strategy of electroreductive alpha-hydroxyalkylation. This method offers a broad substrate scope, simplicity in operation, high chemoselectivity, and does not require pressurized H2 gas or transition metal catalysts. The activation of reactants by the zinc ion generated from anode oxidation plays a crucial role in this transformation. This strategy, combined with substrate activation by Lewis acids, is expected to lead to the development of more useful transformations.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2023)
Article
Chemistry, Physical
Yang Long, Yanling Zheng, Ying Xia, Lang Qu, Yuhe Yang, Haifeng Xiang, Xiangge Zhou
Summary: A nickel-catalyzed synthesis of aryl nitriles via aryl exchange has been developed. The reaction utilizes cheap and easily handled 4-cyanopyridine as the cyanating source, allowing for the efficient conversion of various aromatic amides into aryl nitriles. The reaction exhibits wide substrate scope, good selectivity, and is complementary to traditional methods. Additionally, the mechanism is supported by the determination of two key nickel complexes through X-ray crystallography.
Article
Chemistry, Organic
Ya-Zhen Du, Yu-Jiao Wang, Qing-Yang Zhao, Li-Ming Zhao
Summary: This study describes two types of C5 functionalization reactions of chromones with allyl alcohols, resulting in diverse 5-substituted chromones by modulating the catalysts. Further functionalizations of these 5-substituted chromones were achieved, demonstrating the superiority of this method. Notable features of these new methods include readily available precursors, tunable reactivity, exclusive C5-selectivity, and easy derivatization of products.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
(2021)
Article
Chemistry, Physical
Yuanqi Ding, Xinyi Wang, Donglin Li, Wei Xu
JOURNAL OF PHYSICAL CHEMISTRY C
(2020)
Article
Chemistry, Physical
Hui Lu, E. Wenlong, Liangliang Cai, Zhibo Ma, Wei Xu, Xueming Yang
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2020)
Article
Chemistry, Multidisciplinary
Xin Yu, Xin Li, Haiping Lin, Mengxi Liu, Liangliang Cai, Xia Qiu, Dandan Yang, Xing Fan, Xiaohui Qiu, Wei Xu
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Chemistry, Multidisciplinary
Lei Xie, Huijun Jiang, Donglin Li, Mengxi Liu, Yuanqi Ding, Yufang Liu, Xin Li, Xuechao Li, Haiming Zhang, Zhonghuai Hou, Yi Luo, Lifeng Chi, Xiaohui Qiu, Wei Xu
Article
Chemistry, Physical
Donglin Li, Yuanqi Ding, Xinyi Wang, Wei Xu
Summary: 2D-MOFs incorporating different noncovalent interactions and multiple metal components are complex and less predictable, but a systematic study can enhance our fundamental understanding of the interaction mechanism of noncovalent bonds and lead to further investigations into the unique functions of surface-supported 2D-MOF structures.
JOURNAL OF PHYSICAL CHEMISTRY LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Donglin Li, Luye Sun, Yuanqi Ding, Mengxi Liu, Lei Xie, Yinfu Liu, Lina Shang, Yangfan Wu, Hui-Jun Jiang, Lifeng Chi, Xiaohui Qiu, Wei Xu
Summary: This study focuses on the role of water molecules in driving chiral separation on the surface when RNA base uracil selfassembles into homochiral structures upon water exposure. The findings provide insights into the general role of water molecules in the origin of homochirality in living systems, with implications for other biologically relevant molecules such as amino acids and sugars.
Article
Chemistry, Multidisciplinary
Yuanqi Ding, Lei Xie, Donglin Li, Hanlin Shen, Cuiyu Li, Wei Xu
Summary: Based on STM imaging and DFT calculations, this study provides experimental evidence of the interconversion between G-quartets and G-triads on the Au(111) surface, and reveals the relative stabilities of these two motifs, which enhances the fundamental understanding of the relationship between G-triplex and G-quadruplex DNA structures.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Physical
Xin Yu, Qiang Sun, Mengxi Liu, Wan Du, Yi Liu, Liangliang Cai, Zeqi Zha, Jinliang Pan, Faming Kang, Wenze Gao, Dandan Yang, Xiaohui Qiu, Wei Xu
Summary: On-surface synthesis is a promising strategy for constructing novel carbon-based nanostructures. In this study, the on-surface reactions of 1,1,2,2-tetraiodoethylene and 1,1,4,4-tetrabromo-1,2,3-butatriene were systematically explored. The results showed the feasibility of achieving acetylenic and diacetylenic organometallic polyyne on Ag(110) and Cu(110) surfaces, respectively. The transformation between different structures after annealing indicated a lattice dependence of skeleton reconstruction on the corresponding surfaces.
CHEMISTRY OF MATERIALS
(2022)
Article
Chemistry, Physical
Faming Kang, Wenze Gao, Liangliang Cai, Cuiyu Li, Chunxue Yuan, Wei Xu
Summary: On-surface synthesis has shown advantages in precise fabrication of surface-supported nanostructures, particularly when introducing the alkenyl gem-dibromide group. Selective on-surface reactions, such as homocoupling and hydrogen migration, were achieved on Ag(111) and Ag(110) surfaces, respectively, with lattice-directed selectivity revealed by extensive DFT calculations. This lattice-directed strategy is crucial for steering on-surface reaction pathways towards atomically precise synthesis with high efficiency and selectivity.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Review
Chemistry, Multidisciplinary
Lina Shang, Faming Kang, Wenze Gao, Zheng Zhou, Wei Xu
Summary: The on-surface synthesis of carbon nanostructures has gained significant attention due to their unique properties and wide range of applications. Recent studies have focused on low-dimensional sp-carbon nanostructures, which exhibit structural linearity, small steric demands, and intriguing electronic and mechanical properties.
Article
Chemistry, Multidisciplinary
Lei Xie, Yuanqi Ding, Donglin Li, Chi Zhang, Yangfan Wu, Luye Sun, Mengxi Liu, Xiaohui Qiu, Wei Xu
Summary: Water plays a crucial role in biological self-assembly processes, and studying the interactions between water and organic molecules can provide insights into the mechanisms of biological self-assembly.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2022)
Review
Chemistry, Multidisciplinary
Chi Zhang, Wei Xu
Summary: Understanding the interactions between water and organic molecules or inorganic salts is crucial for studying hydration processes in chemistry. This review provides new insights into these interactions using scanning probe microscopy and theoretical calculations. The study reveals the important role of water in biological self-assembly processes and its ability to assist structural transformation in nanostructures.
Article
Chemistry, Multidisciplinary
Xin Yu, Liangliang Cai, Meiling Bao, Qiang Sun, Honghong Ma, Chunxue Yuan, Wei Xu
CHEMICAL COMMUNICATIONS
(2020)
Article
Chemistry, Multidisciplinary
Xinyi Wang, Yuanqi Ding, Donglin Li, Lei Xie, Wei Xu
CHEMICAL COMMUNICATIONS
(2019)
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)
