4.7 Article

ZnCl2-catalyzed chemoselective cascade reactions of enaminones with 2-furylcarbinols: a versatile process for the synthesis of cyclopenta[b]pyrrole derivatives

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CHEMICAL COMMUNICATIONS
卷 50, 期 17, 页码 2164-2166

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c3cc49191a

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  1. National Natural Science Foundation of China [21272074]
  2. Program for Changjiang Scholars and Innovative Research Team in University (PCSIRT)

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A highly efficient ZnCl2-catalyzed cascade reaction of enaminones with 2-furylcarbinols under mild reaction conditions has been developed. This methodology offers a chemo-and diastereoselective access to functionalized cyclopenta[b]pyrrole derivatives in good to excellent yields.

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