Lipase catalyzed inclusion of gastrodigenin for the evolution of blue light emitting peptide nanofibers

We report lipase catalysed regioselective inclusion of gastrodigenin (p-hydroxybenzyl alcohol: HBA) to a peptide Nmoc-Leu-Trp-OH at physiological pH 7.4. The resultant Nmoc-Leu-Trp-HBA from a reaction cycle of dissipative self-assembly evolves into blue light emitting peptide nanofibers.