A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

Progress in platinum derived drug development

(2014) N.P. Farrell   DRUGS OF THE FUTURE

NanoSIMS multi-element imaging reveals internalisation and nucleolar targeting for a highly-charged polynuclear platinum compound

(2013) Louise E. Wedlock et al.   CHEMICAL COMMUNICATIONS

Heparan Sulfate Proteoglycan-Mediated Entry Pathway for Charged Tri-Platinum Compounds: Differential Cellular Accumulation Mechanisms for Platinum

(2012) Heveline Silva et al.   MOLECULAR PHARMACEUTICS

Biologically relevant metal-cation binding induces conformational changes in heparin oligosaccharides as measured by ion mobility mass spectrometry

(2011) Youjin Seo et al.   INTERNATIONAL JOURNAL OF MASS SPECTROMETRY

Effects of Noncovalent Platinum Drug–Protein Interactions on Drug Efficacy: Use of Fluorescent Conjugates as Probes for Drug Metabolism

(2011) Brad T. Benedetti et al.   MOLECULAR PHARMACEUTICS

Excursions in polynuclear platinum DNA binding

(2010) John B. Mangrum et al.   CHEMICAL COMMUNICATIONS

Determination of the Kinetic Profile of a Dinuclear Platinum Anticancer Complex in the Presence of Sulfate: Introducing a New Tool for the Expedited Analysis of 2D [1H,15N] HSQC NMR Spectra

(2010) Rasha A. Ruhayel et al.   INORGANIC CHEMISTRY

The phosphate clamp: a small and independent motif for nucleic acid backbone recognition

(2010) Seiji Komeda et al.   NUCLEIC ACIDS RESEARCH

Tumorigenic and adhesive properties of heparanase

(2010) Flonia Levy-Adam et al.   SEMINARS IN CANCER BIOLOGY

Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening

(2009) Edward Hammond et al.   ANALYTICAL BIOCHEMISTRY

The Structure of Glycosaminoglycans and their Interactions with Proteins

(2008) Neha S. Gandhi et al.   Chemical Biology & Drug Design

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology