Article
Chemistry, Multidisciplinary
Ana Amic, Dejan Milenkovic, Zoran Markovic, Denisa Cagardova, Jaime Rodriguez-Guerra Pedregal, Jasmina M. Dimitric Markovic
Summary: The kinetics and thermodynamics of phenolic O-H and C-ring C-H bond breaking in dihydrokaempferol, a natural flavonoid compound, were investigated using a density functional based approach. The study found that the 4'-OH phenolic hydrogen is involved in the inactivation of a hydroperoxyl radical (OOH), while the hydrogen atom transfer mechanism is responsible for C-H bond cleavage.
NEW JOURNAL OF CHEMISTRY
(2021)
Article
Chemistry, Applied
Changzhen Yin, Wei Liu, Qiang Wu, Miao Wang, Peng Hu
Summary: A new iron-catalyzed deconstructive cyanomethylation reaction has been developed for the selective functionalization of cyclic and linear alcohols. This reaction involves the cleavage of C-C single bonds and C(sp3)-H bonds, leading to the formation of C(sp3)-C(sp3) bonds.
ADVANCED SYNTHESIS & CATALYSIS
(2023)
Article
Chemistry, Multidisciplinary
Mo Zhang, Zheng Li, Yeqin Feng, Xing Xin, Guo-Yu Yang, Hongjin Lv
Summary: Selective photocatalytic hydrogenolysis of lignin beta-O-4 models was achieved using Ni-containing polyoxometalate (POM) catalysts and CdS quantum dots under blue LED light irradiation. The system demonstrated high conversion and selectivity in transforming lignin beta-O-4 models to phenols and ketones. A potential photocatalytic mechanism was proposed based on experimental and spectroscopic analyses. This facile strategy has the potential for the photocatalytic production of various value-added chemicals from natural or biomass derivatives.
Article
Multidisciplinary Sciences
Daniel A. Strassfeld, Chia-Yu Chen, Han Seul Park, D. Quang Phan, Jin-Quan Yu
Summary: The functionalization of C-H bonds in organic molecules is a direct approach for chemical synthesis. Recent advances in catalysis have allowed various chemical groups to control and direct C(sp(3))-H activation, but alcohols, a common functionality, have remained difficult to react due to their low affinity for catalysts. This study describes ligands that enable alcohol-directed arylation of C(sp(3))-H bonds through charge balance and hydrogen-bonding interactions, thus enhancing substrate-catalyst affinity and enabling previously unknown reactivity.
Article
Chemistry, Multidisciplinary
Chengwei Liu, Chong-Lei Ji, Tongliang Zhou, Xin Hong, Michal Szostak
Summary: Cooperative bimetallic catalysis was used in the direct decarbonylative heteroarylation of carboxylic acids, enabling synthesis of important heterobiaryl motifs with high chemoselectivity. This method, which does not require prefunctionalization or directing groups, has a broad substrate scope and shows potential for late-stage modification of pharmaceuticals and streamlined synthesis of bioactive agents. Extensive mechanistic and computational studies were conducted to understand the reaction mechanism, identifying a key step involving the intersection of two catalytic cycles.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2021)
Article
Chemistry, Multidisciplinary
Alexander Purtsas, Marco Rosenkranz, Evgenia Dmitrieva, Olga Kataeva, Hans-Joachim Knoelker
Summary: In this paper, the oxygenation and amination reactions of tertiary arylamines are described. The key steps of these coupling reactions involve iron-catalyzed oxidative C-O or C-N bond formation, which typically provide the desired products in high yields and with excellent regioselectivity. These transformations are carried out using hexadecafluorophthalocyanine-iron(II) (FePcF16) as catalyst, with the presence of an acid or base additive, and only require ambient air as the oxidant.
CHEMISTRY-A EUROPEAN JOURNAL
(2022)
Article
Chemistry, Multidisciplinary
Kosuke Hirai, Yuki Homma, Tatsuyoshi Ito, Nobuharu Iwasawa, Jun Takaya
Summary: The photoreactivity of three-coordinate triarylboranes with a neighboring Lewis base moiety was investigated in this study. It was found that o-Anisyldimesitylborane underwent skeletal rearrangement under photoirradiation conditions, leading to the formation of (2-benzyl-4,6-dimethylphenyl)-mesitylborinic acid after hydrolysis. Experimental studies and theoretical calculations supported that the reaction proceeded via a triplet excited state and involved C-H abstraction and radical coupling to form a spiro boracycle intermediate. This study revealed the unique difference in photoreactivity of triarylboranes depending on the neighboring Lewis base moiety.
Article
Chemistry, Physical
Yaxuan Jing, Mohsen Shakouri, Xiaohui Liu, Yongfeng Hu, Yong Guo, Yanqin Wang
Summary: Researchers have developed a strategy to selectively cleave C-C bonds in aromatic plastics using catalyst Ru/Nb2O5 through methanol poisoning, resulting in monocyclic phenolic compounds.
Article
Chemistry, Multidisciplinary
Hairong Lyu, Zuowei Xie
Summary: A unique approach to vertex-selective catalytic B-H amination has been developed, allowing the reaction to occur at either the B(3)- or B(4)-position in o-carboranes. By using different transition metal catalysts, the dehydrogenative BH/NH cross-coupling of o-carboranes and free amines has been achieved, resulting in a wide variety of B(3)- or B(4)-aminated o-carboranes with high regioselectivity.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Canlin Zou, Hongting Wu, Jiangtao He, Yunfei Hu, Weijie Deng, Xinling Li, Jinhui Hu, Yibiao Li, Yubing Huang
Summary: An efficient anodic C(sp(3))-H acyloxylation protocol has been developed, which enables the direct oxidation of indolin-3-ones to obtain various C2-acyloxy indolin-3-ones without the need for metal catalysts and external oxidants. The practicality of this protocol has been demonstrated through the effective application of several medical drugs and gram-scale experiments.
JOURNAL OF ORGANIC CHEMISTRY
(2022)
Article
Chemistry, Physical
Takanori Iwasaki, Wataru Ishiga, Shrinwantu Pal, Kyoko Nozaki, Nobuaki Kambe
Summary: This study reports the mechanistic investigation of the Rh-catalyzed cross-coupling reaction between vinylic ethers and aryl Grignard reagents. The presence of olefinic ligands significantly affects the catalytic activity of Rh precatalysts. Computational studies reveal that the reaction proceeds through Mg cation-assisted insertion/anti-beta-oxygen elimination, with the Mg countercation coordinating to the ethereal oxygen atom in the transition state.
Article
Chemistry, Physical
Takanori Iwasaki, Wataru Ishiga, Shrinwantu Pal, Kyoko Nozaki, Nobuaki Kambe
Summary: This study presents a mechanistic investigation of the Rh-catalyzed cross-coupling reaction between vinylic ethers and aryl Grignard reagents. Kinetic studies reveal first-order and zeroth-order kinetics with respect to the vinyl ether and aryl Grignard reagents, respectively. Computational studies suggest that the reaction proceeds through Mg cation-assisted insertion/anti-beta-oxygen elimination. The results demonstrate the unique chemoselectivity of the Rh-catalyzed reaction.
Article
Chemistry, Multidisciplinary
Kaito Kuroki, Tatsuyoshi Ito, Jun Takaya
Summary: By utilizing a photo-promoted skeletal rearrangement reaction, borabicyclo[3.2.0]heptadiene derivatives were successfully synthesized via boron-insertion into aromatic C-C bonds. The reverse reaction of dearomatized products was observed to occur in the dark at room temperature, achieving a photochemical and thermal interconversion between triarylboranes and boron-doped bicyclic systems.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2023)
Review
Chemistry, Physical
Hao Zhou, Yaxuan Jing, Yanqin Wang
Summary: This article discusses the importance of sustainable fuels and chemicals in achieving global carbon neutrality. It focuses on the catalytic activation and cleavage of C-O/C-C bonds in biomass conversion, highlighting the challenges and possible strategies using cooperative catalysis. The article mainly discusses the activation and cleavage of C-O bonds and the cleavage of C-C bonds in carbohydrates and lignin, offering insights and future directions for research in this field.
ACTA PHYSICO-CHIMICA SINICA
(2022)
Article
Chemistry, Organic
Jin Zhang, Pei Zhang, Yangmin Ma, Michal Szostak
Summary: This study reports a novel solvent-free method for synthesizing ketones with high selectivity from acyl chlorides and boronic acids. The reaction takes place in the solid state, without the use of solvents, and has a short reaction time, demonstrating excellent selectivity for C(acyl)-Cl bond cleavage.
Article
Materials Science, Multidisciplinary
M. C. Palenik, C. A. Klug, M. W. Conroy, S. A. Fischer, D. Gunlycke, B. Dunlap, L. Stevens, P. Zavalij, B. Eichhorn
PHYSICAL REVIEW MATERIALS
(2020)
Article
Engineering, Manufacturing
Jacob C. Simmons, Xiaobo Chen, Arad Azizi, Matthias A. Daeumer, Peter Y. Zavalij, Guangwen Zhou, Scott N. Schiffres
ADDITIVE MANUFACTURING
(2020)
Article
Chemistry, Multidisciplinary
Weijian Xue, Peter Y. Zavalij, Lyle Isaacs
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
(2020)
Article
Chemistry, Physical
Greg Brewer, Raymond J. Butcher, Peter Zavalij
Article
Chemistry, Multidisciplinary
Steven Murkli, Jared Klemm, David King, Peter Y. Zavalij, Lyle Isaacs
CHEMISTRY-A EUROPEAN JOURNAL
(2020)
Article
Chemistry, Organic
Xiaoyong Lu, Sandra A. Zebaze Ndendjio, Peter Y. Zavalij, Lyle Isaacs
Article
Chemistry, Inorganic & Nuclear
Peter Y. Zavalij, Ai-Min Li, Bryan W. Eichhorn
ZEITSCHRIFT FUR ANORGANISCHE UND ALLGEMEINE CHEMIE
(2020)
Article
Chemistry, Multidisciplinary
Xiaoxi Lin, Arkadi Vigalok, Andrei N. Vedernikov
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
(2020)
Article
Nanoscience & Nanotechnology
A. R. Kytsya, L. I. Bazylyak, I. Yu. Zavaliy, Yu. V. Verbovytskyy, P. Zavalij
Summary: Bimetallic Ni-Cu nanoparticles with different (Ni/Cu) ratio were synthesized through a fast and simple reduction process in water/ethylene glycol solutions. The nanoparticles showed polydisperse sizes within 20-70 nm, with the particle diameter slightly depending on the Ni/Cu ratio. Additionally, XRD and EDX analyses revealed changes in lattice parameters and core-shell structure, respectively.
APPLIED NANOSCIENCE
(2022)
Article
Chemistry, Inorganic & Nuclear
A. P. Prakasham, Arkadi Vigalok, Andrei N. Vedernikov
Summary: A series of Pd(II) aryl complexes with a PNO-type pincer ligand bearing a weakly coordinated benzofuran side arm has been studied. The Pd-O distances were found to depend on the aromatic group at the Pd center. Changing the electron density at the metal can affect these interactions and be utilized in chemical reactions.
Article
Engineering, Environmental
Matthew B. Leonard, Tianyu Li, Morgan J. Kramer, Shannon M. McDonnell, Andrei N. Vedernikov, Efrain E. Rodriguez
Summary: The research suggests that CeO2 is the most reactive material, with a surface area normalized rate constant 3-4.6 times larger than TiO2 and CexTi1_xO2 series. Additionally, the nature of the cation is found to be less significant in the reactivity of methyl paraoxon on these MMOs compared to factors like crystal structure type.
JOURNAL OF HAZARDOUS MATERIALS
(2022)
Article
Chemistry, Organic
Michael Hitt, Andrei N. Vedernikov
Summary: N-Trifluoroacetoxyquinuclidinium trifluoroacetate was prepared in situ and used as a reagent for the high-yielding oxidative trifluoroacetoxylation of benzylic C-H bonds. The reaction showed selectivity for 2 degrees benzylic C-H bonds and suggested a hydrogen-atom transfer mechanism for alkylbenzenes.
Article
Chemistry, Inorganic & Nuclear
Jiaheng Ruan, Daoyong Wang, Morgan J. Kramer, Peter Y. Zavalij, Andrei N. Vedernikov
Summary: In this study, two sulfonated CNN-pincer ligands were used to explore the oxidative functionalization of the PtII-Me bond in derived complexes, with O2 and H2O2 as oxidants. Different high-valent platinum complexes were produced depending on the oxidant used, showing the importance of ligand structure on the reaction outcome.
Article
Chemistry, Organic
Michael Hitt, Andrew Norris, Andrei N. N. Vedernikov
Summary: A series of N-aroyloxyquinuclidinium salts were synthesized and used as reagents for efficient three-component Ritter-Mumm-type oxidative C-H imidation reactions. The benzylic C-H bonds of 1 & DEG; and 2 & DEG; substituents were used as limiting reagents, with nitriles as the source of imide nitrogen under photocatalytic conditions. These reagents also showed slightly lower reactivity towards cycloalkanes.
Article
Chemistry, Multidisciplinary
Shrinwantu Pal, Kyoko Nozaki, Andrei N. Vedernikov, Jennifer A. Love
Summary: The study demonstrates complete deuteration of Pt-CH3 fragments through a metal-ligand cooperative mechanism, resulting in the synthesis of (dp)Pt-II(CD3)(2). Experimental results show that the DPK ligand enables Pt-CH3 deuteration, while other model ligands lead to non-rate-limiting reductive coupling reactions.
Review
Chemistry, Multidisciplinary
Dan He, Yawen Li, Fuwen Zhao, Yuze Lin
Summary: High trap density in organic solar cells leads to localized charge carriers and reduced carrier lifetime, limiting device efficiency. This feature article summarizes the recent advances of trap suppression by material design and device engineering.
CHEMICAL COMMUNICATIONS
(2024)
Review
Chemistry, Multidisciplinary
Olivier Monfort, Arshitha Madhusudhan, Martin Motola
Summary: This article presents the advantages of coupling photocatalysis and Fenton-based processes for environmental remediation and discusses their synergy. It critically examines the simultaneous triggering of these two processes and provides insights into research approaches. The study aims to enhance understanding of this complex process and highlight the potential integration of new catalysts in current wastewater treatment technology.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Manideepa Dhar, Chittaranjan Mishra, Avijit Das, Uttam Manna
Summary: An approach of 'polymerization of monomers in its aggregated form' has been introduced to tailor the water wettability of fibrous and porous substrates, achieving hydrophobicity to superhydrophobicity transition, as well as patterned wettability. This facile chemical method provides a durable coating with adjustable and patterned wettability for various potential applications.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Saswat Ranjan Bhoi, Chhanda Debnath, Shikha Gandhi
Summary: In this article, a novel catalytic reaction using Pd(0) and Bronsted acid is reported for the synthesis of biologically important imidazolidinone-fused N-heterocycles through redox-neutral intramolecular N-allylation of indoles and pyrroles with alkynes. This atom-economical method is applicable to a wide range of substrates and eliminates the need for leaving groups or oxidizing agents commonly used in traditional allylation reactions.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Longkun Chen, Mingshuai Zhang, Meichen Liu, Zhuoyuan Liu, Yuetong Qiu, Zhilai Zhang, Fuchao Yu, Jiuzhong Huang
Summary: In this study, an efficient Rh(III)-catalyzed selective mono- and dual-C-H bond functionalization/cyclization with iodonium ylide as the sole coupling partner was demonstrated. Fused benzodiazepine skeletons were obtained in excellent yields, providing an improved approach to dual C-H unsymmetrical functionalization.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Alice Kennett, Sven Epple, Gabriella van der Valk, Irene Georgiou, Evelyne Gout, Romain R. Vives, Angela J. Russell
Summary: This study presents the design and synthesis of sulfated disaccharide inhibitors based on IdoA(2S)-GlcNS(6S), which showed potent inhibition of Sulf-2. The results suggest that IdoA(2S)-GlcNS(6S) is the shortest fragment size required for effective inhibition of Sulfs, and a trisulfated disaccharide is identified as the minimal fragment size of heparan sulfate for effective endosulfatase inhibition.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Mauro Garbini, Andrea Brunetti, Riccardo Pedrazzani, Magda Monari, Massimo Marcaccio, Giulio Bertuzzi, Marco Bandini
Summary: The self-adaptability of galvanostatic electrolysis was found to be helpful in a multistage chemo- and diastereoselective electrochemically promoted cyclodimerization of chalcones. Through a series of reductive events, densely functionalized cyclopentanes with five contiguous stereocenters were obtained (25 examples, yields up to 95%, dr values up to >20:1). Further experimental and electrochemical investigations indicated the crucial role of dynamic kinetic resolution of the aldol intermediate in the reaction mechanism.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Dhananjay S. Nipate, Neha Meena, Prakash N. Swami, Krishnan Rangan, Anil Kumar
Summary: In this study, the synthesis of functionalized benzo[a]phenazines and indazolo[2,3-a]quinolines was achieved through Rh(III)-catalyzed oxidative annulation of 2-arylquinoxalines and 2-aryl-2H-indazoles with allyl alcohols. The method showed a wide substrate scope, excellent functional group tolerance, good to high yields of annulated products, and the capability for scaled-up synthesis. A tentative mechanism of the annulation reaction was proposed based on a preliminary mechanistic investigation.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Ruonan Zhang, Abudukadi Tudi, Xia Yang, Xuping Wang, Zhihua Yang, Shujuan Han, Shilie Pan
Summary: A new lead tellurium borate material with a unique fundamental building block [B4O10] was synthesized and found to exhibit high birefringence. The structure-property relationship was discussed using first-principles calculations.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Amresh Kumar Singh, Baishali Thakurta, Anupam Giri, Monalisa Pal
Summary: This study introduces three key concepts for the quick synthesis of large-scale high-quality 2D materials films and their utilization in device fabrication.
CHEMICAL COMMUNICATIONS
(2024)
Article
Chemistry, Multidisciplinary
Reina Hagiwara, Shun Nishimura, Kosuke Okeyoshi
Summary: A copolymer-conjugated nanocatalytic system has been developed to improve electron transfer and enhance photoinduced H2 generation.
CHEMICAL COMMUNICATIONS
(2024)