Development of a highly potent, selective, and cell-active Inhibitor of cysteine cathepsin L–A hybrid design approach

Development of cell-active non-peptidyl inhibitors of cysteine cathepsins

(2013) Dibyendu Dana et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Identification of new peptide amides as selective cathepsin L inhibitors: The first step towards selective irreversible inhibitors?

(2013) Ana Torkar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

The Marine Cyanobacterial Metabolite Gallinamide A Is a Potent and Selective Inhibitor of Human Cathepsin L

(2013) Bailey Miller et al.   JOURNAL OF NATURAL PRODUCTS

Inhibition of cathepsin L lowers the apoptotic threshold of glioblastoma cells by up-regulating p53 and transcription of caspases 3 and 7

(2011) Saša Kenig et al.   APOPTOSIS

Activity-based probes: discovering new biology and new drug targets

(2010) William P. Heal et al.   CHEMICAL SOCIETY REVIEWS

Novel Peptidyl Aryl Vinyl Sulfones as Highly Potent and Selective Inhibitors of Cathepsins L and B

(2010) Laura Mendieta et al.   ChemMedChem

Structural basis for reversible and irreversible inhibition of human cathepsin L by their respective dipeptidyl glyoxal and diazomethylketone inhibitors

(2010) Rajesh T. Shenoy et al.   JOURNAL OF STRUCTURAL BIOLOGY

Cathepsin L, target in cancer treatment?

(2009) Jacqueline M. Lankelma et al.   LIFE SCIENCES

Exploring Inhibitor Binding at the S′ Subsites of Cathepsin L

(2008) Shafinaz F. Chowdhury et al.   JOURNAL OF MEDICINAL CHEMISTRY